One of the three patients was participating in a famciclovir trial and the other two were receiving lamivudine therapy for active hepatitis B infection. All three patients had documented hepatitis B flares, and all had hepatitis B virus DNA detected at that time. All patients developed decompensated liver disease despite one patient having had a prior liver biopsy showing absence of cirrhosis.
I am a 26 year old male having hbsag and hbeag=+ve,hbv dna =1070 iu/ml(Taqman) but my LFT results are normal(sgpt=37,sgot=33).My doctor has asked me to take lamivudine 100 mg for 6 months or until it becomes -ve.My mom is taking lamivudine for the last 7 months after her hbv dna crossed 8 lacs iu/ml.Probably I have been infected from my birth.Is it possible for both of us to completely cure Hep. B after taking lamivudine.
Please I need help. I was diagnosed of having Hepatitis b five years ago. D Doctor advised me to use Lamivudine which I did. Two months ago i did the test again and it showed that I am positive. I was advised to do Liver scan and HBD DNA Viral Load. The scan showed that my Liver is ok but the Viral load was 2,400 IU/ml. what can i do? The Doctor want to refer me to a consultant in Benin City of Nigeria.
If chronic then u definetly require treatment, involving antiviral drugs such as lamivudine?
The study sampled 1,000 physicians, including internists, primary care providers, and gastroenterologists to determine this group’s knowledge about hepatitis B, and their capability to effectively assess patients’ risk for hepatitis B and immunize and screen them.
Researchers created a survey featuring four fictional case histories that described patients at high risk for contracting HBV, followed by questions regarding knowledge, attitudes, and beliefs of HBV screening and vaccination.
I would like to know if it is a commune side effect of Hepatitis B or if Lamivudine could have such an effect.
Thanks for your help.
A total of 283 patients with chronic hepatitis B virus (HBV) infection (245 patients with chronic hepatitis B and 38 inactive hepatitis B surface antigen carriers) were included in the study. The HBV genotype was determined by using quantitative real-time polymerase chain reaction and sequence analysis, and tyrosine-methionine-aspartate-aspartate (YMDD) motif mutations were determined using the reverse transcriptase hybridization method.
> greetings of peace to everyone, i was diagnosed with chronic hepatitis b and was confined for 12 days. sgpt was 7000 on the first days then down to around 600 by the time i was discharged. a week after discharge, sgpt was down to 240. no liver biopsy nor fibroscan was done. hbv-dna was 1620 IU/mL. the doctor said i will have the dna count after 5-6 months. im on a strict diet, low protein, fruits and vegetables. i am taking lamivudine and vitamin k.
Well...Did you read this article?
http://www.hivandhepatitis.com/hep_b/news/2010/0406_2010_a.html
(Traditional Chinese Medicine May Perform Better than Interferon or Lamivudine for Chronic Hepatitis B), many natural things heal many things but we don't necessarily know about them.
20,000 IU/mL (105copies/mL), lower values 2,000- 20,000 IU/mL (104-105 copies/mL) are often seen in HBeAg-negative chronic hepatitis B; 3. Persistent or intermittent elevation in ALT/AST levels; 4. Liver biopsy showing chronic hepatitis with moderate or severe necroinflammation.
Inactive HBsAg carrier state: 1. HBsAg-positive >6 months; 2. HBeAg-, anti-HBe+; 3.
this might be a very good choice for those with kidneys problems or high creatinine
Antiviral Telbivudine Appears to Protect Kidney Health
The antiviral telbivudine (Tyzeka), may not be as potent as other hepatitis B antivirals, but it appears to have a unique quality—it appears to “protect” the kidneys against damage usually linked to antiviral treatment, according to an article in the December issue of the Journal of Viral Hepatitis.
TDF switch effective in Asian chronic HBV patients
Posted in Hepatitis News
Switching therapy to tenofovir disoproxil fumarate is effective in treatment-resistant chronic hepatitis B, show results from a cohort of Asian patients. Administration of TDF resulted in a sustained virological response in the majority of nucleos ide analogue -experienced patients after nearly 2 years of follow-up, report the researchers.
Ziffix is Lamivudine, which should not be used as it builds resistance and mutations, which may hamper future treatment and leave you in worse shape. The 2 first line oral antivirals are Entecavir or Tenofovir. You need change medications if you require medication for your HBV.
2 x ULN, then, observe for 3-6 months and treat if no spontaneous HBeAg loss. Consider liver biopsy prior to treatment if compensated. Immediate treatment if icteric or clinical decompensation. IFNa/pegIFNa, LAM, ADV, ETV, TDF or LdT may be used as initial therapy. ADV not preferred due to weak antiviral activity and high rate of resistance after 1st year. LAM and LdT not preferred due to high rate of drug resistance. End-point of treatment – Seroconversion from HBeAg to anti-HBe.
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