1 Does this mean I do not respond to Tyzeka?
2. Should I change to Ziread since it is approved.
3. I have experienced elbow pain, left arm, with Tzyeka.
4. Does changing drugs instead of stopping altogether cause flare up?
Previouusely I took EPIVIR for 7 years and Hepsera for one year.
Thank you.
I was diagnosed Hep B 13 years ago, and have taken Epivir since 2002. I do blood test and ultra-sound every 6 months and Hep B is controlled pretty well. As you know, Epivir cause virus mutant resistance, and chance is higher for me since I have been on it for 5 years. My doctor gave me 2 choices,
1) "don't fix it until it breaks" - continue with Epivir, move to combo treatment when mutant and resistance evidence shows up.
2) "precautious way" - take baraclude.
s T-cell counts. Tenofovir may also help control Hepatitis B. It also works against several strains of HIV that are already resistant to AZT, ddC, or ddI.
Possible Side Effects:
Headaches
High blood pressure
A general sense of feeling ill
Nausea
Vomiting
Loss of appetite
Increase of enzymes in the kidney and liver that may indicate damage to these organs
Reduction of bone mineral density
For more information, please visit Viread.
One of the three patients was participating in a famciclovir trial and the other two were receiving lamivudine therapy for active hepatitis B infection. All three patients had documented hepatitis B flares, and all had hepatitis B virus DNA detected at that time. All patients developed decompensated liver disease despite one patient having had a prior liver biopsy showing absence of cirrhosis.
I treated with hep b 14 years ago for 1.5 years with epivir and got hbv e antibodies and afterwards, I stop epivir and every 6 months I check my liver function and alt and ast are persistently normal. I started to check hbv dna 6 months ago as new guidelines come out. Hbv dna at six month was 5000 iu/ml and last week I checked it was 8000 iu/ml. Again both times my alt and ast are normal. As a matter of fact they are in low side of normal.
Nucleoside/nucleotide analog antivirals such as tenofovir, entecavir (Baraclude), adefovir (Hepsera), and lamivudine (Epivir) are the mainstay of chronic hepatitis B treatment. Although they can effectively suppress hepatitis B virus (HBV) replication while on therapy, they typically do not eradicate the virus and therefore may need to be taken long term. Viral suppression has been shown to improve liver fibrosis and reduce the risk of complications such as liver cancer.
Epivir=Lamivudine, said to be very safe for husband and wife who wish to have children. But do you have to choose Lamivudine as first-line treatment with its high resistance profile?
Hi everyone,
I went to see my Dr today and he recommanded to change my medicine to Viread (I am on Epivir more than 2 years). I am wondering if it's necessary to change it now since Epivir works well with me (my DNA is 200 copies). But he was worried about resistance and mutation. Do I have to listen to him? I got Viread today but I am not sure I would start taking it from today.
-Natalie
p.s.: Do you guys drink coffee? I started drinking coffee about 4 months ago...
They see evidence of Hep b also, maybe from a vaccine, they say, so have been on Epivir, a drug used for HIV and hep b. The pharmacist seems skeptical and it is $500.00 per month, ins. won't cover. Wading through all this. Thanks for your answer. I would love to hear about your tx. Are you finished? Do you feel better? Did your hair fall out and were you sick badly? I am just starting on this path and haven't talked to anyone yet. This is great to talk to others.
Just wondering, I had a liver transplant three years ago. They said the donor had a HBV antibody but they did not detect HBV. I decided to go ahead and go through with the the transplant. The doctors said 1 to 2% chance of HBV appearing. I had been vaccinated (the three shots) about 15 years earlier and so I have HBV antibodies.
After the transplant my doctors said I should go ahead and take Epivir just in case they'd missed something.
These drugs were previously approved, but are no longer recommended for use with Hepatitis B, for various reasons. Some of them lead to resistance (the virus mutates and becomes immune to this and sometimes many other medicines) and some of them have too many dangerous side-effects. If your doctor recommends these, either be fully aware of what you are doing, or change doctors immediately.
Does this help?
"An appropriate time to alter therapy by switching to or adding another drug is treatment failure, either primary treatment failure or an inadequate response while receiving treatment with oral agents. The definition of primary treatment failure is a serum HBV DNA decline of less than 1 log10 IU/mL from baseline at week 12 of treatment, whereas an inadequate virologic response is defined as a serum HBV DNA ≥ 2000 IU/mL at week 24 of treatment.
t remember, should I take the AZT with my Viread and Epivir for a more potent PEP regimen? Or is Viread and Epivir alone okay? I have no side effects from them.
Given that this is a gay sex club in NYC, an epicenter of the epidemic? Is it possible to forget having anal sex as a top? I am not a frequent visitor to sex clubs. I do have a phobia of "forgetting" anal sex when I'm drunk- though I've never forgotten it ever before.
I was wondering given the following conditions - 1) HBV is UND (<357/IU) 2) On Epivir for the last several years because after some surgery the doctors thought it was possible I had been exposed to HBV or got some tainted blood 3) previously had the HBV vaccine 15 years ago. 4) No signs of HBV.
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