Thanks smittygirl. I was on the fence with this decision but leaning in the same direction as your perspective. Sunday, today, is my injection day. I've had the p.i. for a week, and it seems to be clearing up despite the Enbrel. So like you, I agree; I'd rather itch a little, then have the chest-wall pain (my main symtom). BTW... good luck with AS. Prior to joining this forum, I read some of the past posts, and yours came forward as a real success story.