A new doctor has put me on it in conjunction with
Enbrel because I have couple joints which have been causing me
problems. Otherwise, I've been great on Enbrel. I am now in my 3rd week on MTX, and seveal joints are really flaring. I find this very depressing. The GI tract challenges, fatigue and foggy brain are a pain, but my arthritis now seems worse in general. Has anyone out there experienced this type of problem, and does it subside? I am about to abandon the MTX ship.