peg intron injection

t have as good as a viral load drop as I did with the Peg-Intron. I had more sides with the Peg-Intron but a bigger viral load drop. I hope for you, that all the rest of your treatment day are sides free.

As a result of its controlled-release mechanism, Locteron was dosed half as frequently as PEG-Intron. PEG-Intron is one of two currently marketed pegylated interferon products for the treatment of hepatitis C, a market that currently exceeds $2.5 billion in worldwide sales. Additional results from SELECT-2 demonstrated the substantial tolerability advantages of Locteron.

I took my first injection a few days ago and Peg-Intron completely wiped me out with feel and aches and pains but I am trying to accept what is to come and hope that my experience with the first tratment will help me. I thank everyone for your help.

s weight is 60 kg and dr. recommend her 80 microgram dose of peg-intron injections with 400mg Virex capsulse. While I have read on Peg-intron literature that its dose is given by weight. For monotherapy use 0.5 microgram/kg/week. For combination therapy 1.5 microgram/kg/week...i think my mother case is combination therapy (injections + capsules).And for 60 kg weight injection dose should be 100 micrograms. Please advise.

SVR for Peg-Intron plus Rebetol combination therapy is 41% for genotype 1, and 82% for genotypes 2 through 6. Peg-Intron is a reconstituted powder that is dosed according to a person's weight. Roche’s Pegasys plus Copegus: SVR for Pegasys plus Copegus combination therapy is 44-51% for genotype 1, and 70-82% for genotypes 2 through 6. Pegasys is a ready-made solution that is dosed at 180µg regardless of a person's weight.

t think there will be a problem with changing to Pegasys once your Peg-intron runs out. They both are very similar. My husband has taken both and the Pegasys was a much better experience for him than the Peg-intron. There should never be any interuption time in shots or Riba. This is a hateful virus and you can't give it any chance or it will find a way to live on. Missing doses is a very bad idea so if you change, you've got to make sure there are no gaps in delivery.

Yes they are different molecules. Pegasys (alpha 2a) is a larger molecule and stays in the body longer at higher concentrations. Pegintron (alpha 2b) is a small molecule and a week after injection the concentration in the body is very low. if you search you will be able to find studies that support either one being more effective. some people don't cure with one, but are able to cure with the other.

I asked my doctor for pegasys over peg intron. He addressed my concerns and told me sx's for me would be similar with either drug and kinetics were similar for both with regard to initial suppression of the virus. I had read about peaks and troughs with peg intron. He said that was dated info. Ok, so we decided to stay with peg intron. Now...about dosage. Can anyone explain why pegasys is one dose fits all and peg intron is weight based? I will get 80 mcg with weight at 114 lbs.

explained it like this, “since the Riba has such a longer half-life than Peg Intron there is no need to continue taking it after my final injection.” In no way am I suggesting you stop taking it after your last injection. I would advise you to contact your Dr. and do what he says.

I just took my first shot of Peg Intron Friday night, and I got pretty sick, but thank God after I stayed in bed the next day I felt better. Do these reactions happen every time you inject it or does your body eventually get use to it. Also my viral load is only 300 and I have genotype 1. Can anyone give me more information about my Hep C being cured after this treatment or does it ever get cured?

However, there are newer versions called Pegulated interferons (Pegasys or Peg-Intron), which only need to be injected once a week. There is also Infergen, which is most often a daily injection.

one capsule for stomach, 1 tablet for body ache etc.. with this i m doning my job.. i have two questions: 1. games reduce my stress. can i play bedminton etc? i play it, but people ask me not to do so... 2. i am coping up with side effects, but the thing i m sick of, it Piles..hemmoriods cause a hell of pain for me.. i have this problm since last 10 years. but it was not that much painful before treatmnt..

Pegasys sx seem to peak 3-4 days after injection, may be somewhat milder, and sometimes take several weeks to build up -- all this probably due to the branched PEG molecule and slower absorbtion/elimination. Peg-Intron seems to peak a couple days after injection. If I can find a graph that shows peak levels I'll post it to this thread. Someone had it on their home page and it seemed to conform what a lot of people have experienced.

He uses Pegasys and my GI doctor (whom I love) uses peg-intron. My question for all peg-intron users is how bad have your sx been? The doctor I saw today said pegasys seems to have less sx, but of course not all people react the same way. I love my GI doctor and want to treat with him, but am I making a mistake by going Peg-Intron? Thanks for your input. My stats: 26 years old, really healthy, active female, geno 3a, VL 949,000. No biopsy done Thanks!

I was told to test on the day before by injection so that the peg-interon would be at it's lowest level, and therefore I would have the most accurate determination of my viral load. I was told that the peak was for 5 days after the shot, and the trough, was on days 6 and 7. I got that info from other forum members. I have read since then, that after one week the peg is maintained in the body at a steady level.

Just confirm that she had used Peg-Intron (pegelated) or Intron (simple interferone) previously. I think your mom should consult with good specilaist as he/she will first assess the condition of your mom whether she is in condition to support Treatment or not. seems to be from Pakistan or india ???

s shorter and linear-chain PEG, Peg Intron has a half-life of 30-50 hours. (Note that NPIA or non-pegylated interferon alfa has a half-life of only 3-5 hours.) 3) …multiple-dose ribavirin half-life (298 hours) is considerably longer than the single-dose half-life (79 hours) Questions: #1 What extent does RIBA prolong the half-life of the Pegasys and the Peg Intron? #2 Am I phrasing the question right? Is this how it works?

Well, if your HBV DNA wasn't all that high before your Peg Intron, it's not surprising that you would go UND. As long as you stay HBV DNA UND on Peg Intron, your HepB is being managed well. It's obviously the desired outcome. Here's the thing, you have a timeframe for Peg Intron for HCV treatment. I think your doc will stop Peg Intron based on HCV because there's no timeframe for HBV.

My experience was that Pegasys was much much easier to tolerate than was Peg-Intron. I treated with both interferons and Pegasys was literally a walk in the park compared to Peg-Intron. I think the efficacy is pretty much equal with Pegasys perhaps having a slight edge. It was the tolerability of Pegasys that enabled me to extend my treatment duration and achieve SVR.

I don’t know which meds you’re taking; Pegasys or PEG-Intron, but you might consider calling their patient hotline and bring this up with their educating nurse. From the years I’ve been in here, I don’t believe an *excursion* to room temperature for a day or two will break down the proteins involved. Northern hemisphere=cool ambient temperatures? Better to confirm this with someone authoritative, though :o). Can you ask the flight attendant to put the container in the on board refrigerator?

I finished treatment with Peg-Intron and Ribavirin in 2007, after a 24 week course. I acheived non-detectable levels of HCVRNA after 4 weeks of treatment. I have, however, since relapsed. My current doctor would like to retreat with Infergen and Ribavirin, with the belief that the HCV virus has developed some form of immunity to the pegylated interferon.

"180" is the standard dosage for Pegasys. You state you're on "Peg Intron" which is made by a different manufacturer and dosed differently by weight. The most common forumulations of Peg Intron need to be refrigerated and I therefore assume so does yours since it was shipped in a styrofoam container. The ribavirin can be stored at room temperature. Like in your case, my ribavirin was also shipped in the styrofoam along with the peg.

Depends on which PegIFN you're doing. Pegasys and Peg-Intron have different times they reach peak levels during the week. I took my Peg-Intron at noon Fri. and usually felt OK to be back at work Mon. People doing Pegasys sometimes feel the most sx a few days later. As for bloodwork, I had blood drawn on Wed. and had gastro appts. on Fri., every week the first 6 weeks and once a month after that.

I was taking Incivek, ribaviran and peg intron. I had a pre surgery physical today and my EKG came up slightly abnormal than the previous one I had before treatment. My question is can the aftermath of these drugs affect the heart? I'm supposed to have a meniscus repair done on the 27th and my cardiologist suggests I have a CT scan of my heart. Any insight would be appreciated.

Peg intron injection

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