http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/500253.html
and did find some info on skin changes ..
"Less common or rare
Depression of the skin at place of injection; thickening of the skin at place of injection; ..." This doesn't mention cellulite directly, but it sounds similar.
The site also has a clear caution to discuss these or any other changes with your doc.
Examples are insulin zinc suspension, protamine zinc insulin, and the insulin analogues insulin glargine and insulin detemir. The latter two insulins are now the most widely used long-acting insulins.
* Biphasic insulins: mixtures of short-acting and intermediate-acting insulins in different proportions, such as 30/70, 50/50. Examples are NovoMix 30, Humulin M3, Insuman comb and Humalog Mix25.
Insulinotherapy was initiated with glargine, ten units at bedtime (glycemic value before aministration was 169) after reiceiving 6 units of aspart imediately (7 pm). Next day a fasting value of 140 mg/dl. Bedtime value (2 hours postprandial ) 269. After 10 U glargine, fasting value 120 mg/dl. Glycemic variation are very important and depend on the thyroid status.
What is your opnion? Is this a temporary glycemic instability, type 2 or type 1 diabetes?
You may want to check on the 6 hour duration, many insulin experts will recommend you use 4 hours as the length of the insulin duration. So your blood sugar rises because of the immediate release into your system of the carbs in the ice cream, flooding your bloodstream with carbs, and the insulin takes a bit to get working.
I, like you, have noticed a definite peak between 4-5 hours after taking the Lantus, so taking it in the morning makes this peak mean that i require less morning quick-acting insulin to cover my breakfast. Like you, also, I noticed elevated morning sugars, and I have fixed this problem by doing the spilt dose. so some insulin is working well through the night. In my case, I take my larger dose (2/3 of my total) in the morning, and I take 1/3 of my total daily dose at bedtime.
between bedtime and breakfast I am having a drop in BGs of around 10-13 mmols. and then in the mornings, after breakfast BGs shoot up, so my normal carb-insulin ratio doesnt work well.
I cannot understand why this overnight drop is happening, which is becoming scary. I tested BGs during the night and there seems to be a drop of 2 mmol/hour. I am forced to go to bed with readings around 20, so that I will wake up with 7-8.
I also found some books that calculated the amount of insulin to use and gave the peak arc and life span of each type of insulin. My most recent one was Dr. Bernstein's - although I now dispute his protein diet as red meat does horrible things to my gut. I find that humalog is nifty but that regular did a better job on the longer-digesting proteins and fats (unless you use Lantus as the long-acting insulin with humalog). Hope that helps.
m I on too much medication as my blood sugar are still not under control, they are still going up and down just like a mountain peak, How much insulin will I need to be able to control my sugar and will I come off the metformin when that happens, I am also a bi-polar manic depressive patient and I am very depressed at thsi point due to the fact of the new use of insulin and things just don;t seem to be going in the right direction I am very confused, I have considered going in to see my internis
s another good tool for figuring out how much insulin to take when you eat. If your insulin is peaking at dinnertime, that means it's at it's strongest level and then it's downhill from there. So even if it's low before you eat, there is probably not enough left in you to take care of what you are eating for dinner. You may have to take a little less regular insulin at dinner, but you will probably have to take some.
MY DOCTOR PRESCRIBED LANTUS INSULIN TO REPLACE THE HUMULIN L INSULIN THAT I HAD TAKEN FOR SEVERAL YEARS. I HAVE NOTICED THAT WHEN I TAKE THE LANTUS INSULIN PRESCRIBED DOSAGE(S) THAT APPROXIMATELY 15-30 MINUTES LATER I START TO SWEAT PROFUSELY. IS THIS A NORMAL REACTION TO THE LANTUS INSULIN? I VOICED MY CONCERNS TO MY DOCTOR AND HE HAD NO COMMENT. I AM ALSO TAKING SEVERAL DOSES OF HUMULIN R AND HAVE GAINED WEIGHT SINCE I STARTED TAKING THE LANTUS. PLEASE ADVISE. THANK YOU.
One thing which startled me was that when you said Glargine insulin has a peak hour. I visit a non private hospital to do my diabetes follow up once every 4 months and sometimes these doctors are soo busy as they have so many patients to look at. Thats why i m asking help over here..thanks.
When i asked my doctor the last time, he said no way..
At this point, the adjustment to insulin doses is generally done EACH day, according to when the peak action of whatever type of insulin the diabetic person is taking. So if your glucose levels have not improved after several days on insulin with glucose readings still running between 400-600, I would certainly call my physician and tell him or her that this is not acceptable diabetes management in your opinion and ask him or her what changes to make.
You take one shot of it for your long acting insulin, and you still need to take a fast acting insulin to cover your corrections and meals. It is provides a fairly constant basal insulin all day long. 70/30 mix has both, fast acting insulin to cover a meal, and long acting to provide that basal between meals.
Here is a listing of different types of insulins and their details:
http://www.childrenwithdiabetes.com/d_0n_110.htm
To me, the basic difference is variability and flexibility.
I agree with you that slow digestion would probably cause a low at first, followed by high sugars hours later. I have noticed that if I eat a meal that is heavy in fats (fats slow digestion time of the carbs in a meal), such as french fries (NO, I do NOT make a habit of eating stuff like this!), I have to wait until about a half hour AFTER I eat to take my Novalog so the insulin doesn't peak before the carbs digest.
Hello, Sherry. I'm so glad that you are taking the opportunity to learn as much as you can about how to manage diabetes, that's not something that everyone in your position would do.
The first step to learn more is to contact her nurse practioner to get hooked up with a dietician, and in particular one that specializes in diabetes. It is important to understand nutrition and how it relates to controlling blood sugars.
I have recently changed to new insulin. I am now taking Levemir in the morning and at night taking Apidra. Since I have changed to this insulin my blood sugar is going upby alot. I was at 176 this morning and within a few hours it was at 296. This has never happened before and I have not changed anything in my eating. Why is it going up so much and how can I make this stop?
Have you checked with Medicare, Medicaid, PEAK? Checked with your city or county Human Services if they offer an medical assistance program?
According to our doctor and the insulin manufactures insulin should be taken at the same time every day- Especially if it is NPH or Lantus. These long lasting insulin peak in a certain amount of time, then the blood sugars start to rise.
We solved this problem by myself or my husband getting up, checking her blood and give her shot while she was sleeping or she would get up take her shot and go back to bed. Then we got her the insulin infusion pump.
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