doses between 80 and 120 mgs/day are most effective for preventing HIV
transmission, retention in treatment
, reducing the use of other drugs
, and increasing social productivity.
Overall safety potentially lethal Medically safe, no toxic effects found in patients maintained on methadone for up to 18 years.
Overdose Can die from overdose of narcotics; potentially lethal, even for tolerant individuals death can occur quite fast without proper medical treatment with narcan.