Assuming you are referring to a deviated NASAL septum (FYI there is a region of the heart called the septum), the answer is POSSIBLY. A
deviated nasal
septum, when severe, could impair normal respiratory pattern.
In some cases this has led to loud snoring and even obstructive sleep apnea (OSA). OSA could cause inadequate oxygenation during sleep, putting extra stress on the heart, which has been linked to the development and worsening of atrial fibrillation (AF).