I couldn't lose weight on depo no
matter what I did. Constant exercises, starving, hcg shots, prescription
diet drugs. My family blamed me, not the depo provera. I was heartbroken.
I stopped using depo and switched to Mirena.I still wasn't losing the weight, so I changed from my vegetarian,low cal, low fat diet, which wasn't working, and for 4 months I have been on a zero carb diet and lost 30 lbs in 4 months, Little or no exercise now by the way.