Ribavirin prescribing information

Common Questions and Answers about Ribavirin prescribing information


Avatar m tn http://en.wikipedia.org/wiki/Ribavirin Pharmacokinetics Ribavirin is absorbed from the GI tract probably by nucleoside transporters. Absorption is about 45%, and this is modestly increased (to about 75%) by a fatty meal. Once in the plasma, ribavirin is transported through the cell membrane also by nucleoside transporters. Ribavirin is widely distributed in all tissues, including the CSF and brain.
Avatar f tn Am I the only one on here taking 1,200 mgs of ribavirin, who is going thru Triple Tx? I keep noticing people mentioning lower dosages. I have heard of smaller people taking less, and I am 5'9'', 160 pounds, but I think my Doctor is prescribing this same amount for most of the people in my home group, that I've talked to.
Avatar f tn My physician's assistant called yesterday and said I am anemic and to take a shot of procrit. Also to reduce to 400mg/day ribavirin instead of my 800mg. I am in week 15 and have been UND at week three on triple therapy with incivek. Genotype 1a. Weigh 140 lbs. I was on 1000mg for 6 weeks and for the remainder of the time have been on 800mg. Yesterday I started on 400 mg and am worried about relapse. What is the role of ribavirin and just how important is it to SVR? I am on course for 24 wk.
Avatar m tn I went to see my prescribing APRN and she saw the rash and had me stop the Ribavirin but continue Sovaldi. The next day, I was unable to get out of bed due to the severe appearance of lymphedema in the same leg where the rash appeared. I am now waiting for the ambulance to take me to the ER on advice of my APRN. I am unable to put my feet onto the floor because of the intensity of the pain in both legs. I tried, but I screamed so loudly, I didn't want the neighbors to call the police.
80575 tn?1207135964 Provigil is indicated to improve wakefulness in adult patients with excessive sleepiness associated with narcolepsy, obstructive sleep apnea/hypopnea syndrome, and shift work sleep disorder. The revised prescribing information updates safety information to include warnings regarding serious rash, including Stevens-Johnson Syndrome (SJS) and hypersensitivity reactions, and psychiatric symptoms.
Avatar m tn http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1804105/ The above study also indicates that lean body weight has an impact on levels in the blood. I'm in my first week of triple tx with Incivek so my morning dose of RBV is taken with the fatty meal for that. It's the evening dose that I am not taking with a fatty snack because of the difference in the 8 hour /12 hour dosing schedule.
2030686 tn?1351692148 FULL PRESCRIBING INFORMATION: CONTENTS* WARNING: RISK OF SERIOUS DISORDERS AND RIBAVIRIN ASSOCIATED EFFECTS 2 DOSAGE AND ADMINISTRATION COPEGUS should be taken with food. COPEGUS should be given in combination with PEGASYS; it is important to note that COPEGUS should never be given as monotherapy. See PEGASYS Package Insert for all instructions regarding PEGASYS dosing and administration. 2.
Avatar f tn Personally I would be more concerned with the long term effects of hep c than the temporary side effects of treatment Here is a link to the prescribing information for Viekira Pak it lists common side effects http://www.accessdata.fda.gov/drugsatfda_docs/label/2014/206619lbl.
223152 tn?1346981971 Here is the other concerning factor. I have looked thru the Victrelis prescribing information and can't see any restrictions on starting Victrelis. They do say "subjects with less than a .5 log drop in HCV-RNA at week 4 are predicted to have null response." However, they don't say to discontnue the treatment (I think). However, according to my doctor the insurance companies want to see the 4-week data before they approve the Victrelis.
408795 tn?1324939275 Haven't read it completely yet but it's information and just another shout out that if you deal with depression or other related issues, take your time when it comes to tx. Maybe the fda has noticed that some people who deal with depression have a more pronounced tx outcome than previously thought. Like I said, I not did read it all yet, just the quick once over. Yep, tx and 6 month follow-up period, bigger warning than before, I think. Anyone?
Avatar f tn At times, it may also recommend off-label use of certain drugs or tests or provide guidance for regimens not yet approved by FDA. Readers should consult prescribing information and other resources for further information. Of note, the choice of treatment may, in the future, be further guided by data from cost-effectiveness studies.
493068 tn?1224768915 I completed the 48 weeksof Peg Interferon and Ribavirin Feb 2006 and have never been the same. I cleared the virus so far and feel very positive about this. I have never felt this sick and weak before the treatment. I have memory problems,weakness-fatigue, muscle and joint pain, headaches, severe facial and ocular Rosacea, depression panic attacks. I was very active before treatment going to yoga and work.
Avatar m tn Hi So sorry to hear of your relapse I also relapsed on Sovaldi Olysio but I am GT 1a Unfortunately The prescribing information sheet for Harvoni says "-------------------------------INDICATIONS AND USAGE------------------------- HARVONI is a fixed-dose combination of ledipasvir, a hepatitis C virus (HCV) NS5A inhibitor, and sofosbuvir, an HCV nucleotide analog NS5B polymerase inhibitor, and is indicated for the treatment of chronic hepatitis C (CHC) genotype 1 infection in adults"
13100769 tn?1445372717 Class I, Level A *The dose of daclatasvir may need to increase or decrease when used concomitantly with cytochrome P450 3A/4 inducers and inhibitors, respectively. Please refer to the prescribing information and the section on HIV/HCV coinfection for patients on antiretoviral therapy. ____________________________________ Alternative regimen for treatment-naive patients with HCV genotype 3 infection.
Avatar n tn He was prescribed a treatment of ribavirin and pegintron. He was not monitored until the fourth week when he had spontaneous bleeding in his eyes and as a result has permanent eye damage. After reading about the medications on line it appears that he should have been monitored during the 1st week, 2nd and 4th weeks. Is this not the normal procedure for this type of treatment? If he had been monitored there would not have been the permanment damage to his vision.
Avatar f tn If you read the Ribavirin Prescribing Information for ribavirin, right at the top of the label it says... Indications and Usage for Ribavirin 'The safety and efficacy of Ribavirin tablet therapy for the treatment of adenovirus, RSV, parainfluenza or influenza infections have not been established. Ribavirin tablets should not be used for these indications.
Avatar m tn //www.gilead.com/~/media/Files/pdfs/medicines/liver-disease/sovaldi/sovaldi_pi.
8683847 tn?1410760916 pdf based on the NEUTRINO clinical trial results Also that is per the prescribing information on label usage on the Sovaldi prescribing insert the little paper that shouild accompany the prescription. http://www.gilead.com/~/media/Files/pdfs/medicines/liver-disease/sovaldi/sovaldi_pi.pdf again this is based on the NEUTRINO clinical trial results as well.
181549 tn?1277211196 Before we got into all this she didn't even tell me what he was prescribing. I had to say excuse me could you please tell what he's prescribing? here I sit again 1 hr and 10 min. before closing time.
408795 tn?1324939275 Liver chemistries must be measured before the initiation of treatment and regularly during treatment. See Full Prescribing Information for BOXED WARNING.
Avatar m tn I thought this was important enough to post since some members here may be giving out the wrong information. Also people may confuse taking only Incivek with fatty food and not the Ribavirin. It is just as important to take the Riba with fatty food. Since people take their riba and Incivek at the same time the fatty food will help both meds to be better absorbed. Let me state this again. Ribavirin is better absorbed with a high fat meal.
Avatar m tn Interferon, Interferon + Ribavirin, and Interferon+Ribavirin+Tepavier. I also have compensated cirrhosis. I've had HEPC for over 50 years. Currently I'm on week 4 of Havoni + Ribavirin (1200 mg a day + 1 Harvoni). I read that the recommended duration for we hard-to-treat previous non-responders is 24 weeks, but my clinician is insisting 12 weeks will be good enough and there is no difference in the outcomes for 12 weeks vs 24 weeks. Is this correct data?
Avatar f tn Anemia The primary toxicity of Ribavirin is hemolytic anemia, which was observed in approximately 13% of all Ribavirin/peginterferon alfa-2a- treated subjects in clinical trials. Anemia associated with Ribavirin occurs within 1 to 2 weeks of initiation of therapy. Because the initial drop in hemoglobin may be significant, it is advised that hemoglobin or hematocrit be obtained pretreatment and at week 2 and week 4 of therapy or more frequently if clinically indicated.
173930 tn?1196341998 on the other hand, there are information deficits and fears concerning the mode of infection. The recent analysis clearly shows that HCV-infected subjects consider the public information about the HCV infection as catastrophically bad. The recent data in addition show that elimination of HCV decisively ameliorates quality of life, whereas mental and physical health get increasingly worse with progressive liver disease and unsuccessful antiviral therapies.
Avatar m tn html In Hepatitis C Virus Treatment, Interviewed Experts Indicate That Telaprevir- and Boceprevir-Based Regimens Have Advantages Over Pegasys/Ribavirin in Sustained Virologic Response Telaprevir in Combination with a Long-Acting Interferon and Ribavirin Will Earn Decision Resources' Clinical Gold Standard for Hepatitis C Virus in 2012, According to a New Report from Decision Resources WALTHAM, Mass.
Avatar f tn ABT) is a global, broad-based health care company devoted to the discovery, development, manufacturing and marketing of pharmaceuticals and medical products, including nutritionals, devices and diagnostics. The company employs approximately 91,000 people and markets its products in more than 130 countries. http://abbott.com/news-media/press-releases/abbott-presents-promising-phase-2b-interferonfree-hepatitis-c-results-at-2012-liver-meeting.
Avatar m tn org/posts/Hepatitis-C/Does-Ribavirin-cause-anemia-when-used-with-Sovaldi/show/2088605 PRESCRIBING INFORMATION http://www.gilead.com/~/media/Files/pdfs/medicines/liver-disease/sovaldi/sovaldi_pi.pdf SOVALDI is expensive $86,000. the big question is going to be if your insurance company is going to cover it browse these http://www.medhelp.org/posts/Hepatitis-C/Getting-assistance-with-Sovaldi-on-Medicare--Medicaid--etc/show/2064661 http://www.medhelp.
Avatar m tn Per the prescribing information for Epclusa. There is no 16 week treatment regimen. The prescribing information for Epclusa calls for 12 weeks of treatment either alone or with ribavirin.
Avatar f tn 1 Adverse Reactions from Clinical Trials Experience SOVALDI should be administered with ribavirin or peginterferon alfa/ribavirin. Refer to the prescribing information of peginterferon alfa and ribavirin for a description of adverse reactions associated with their use.
Avatar m tn //www.rxabbvie.com/pdf/viekirapak_pi.