Rebetol prescribing information

Common Questions and Answers about Rebetol prescribing information

rebetol

408795 tn?1324939275 PegIntron in combination with REBETOL (ribavirin) and an approved Hepatitis C Virus (HCV) NS3/4A protease inhibitor is indicated in adult patients (18 years of age and older) with HCV genotype 1 infection (see the Package Insert of the specific HCV NS3/4A protease inhibitor for further information).
1711722 tn?1356491154 • PegIntron + REBETOL for 48 weeks (PR48). • PegIntron + REBETOL for four weeks followed by VICTRELIS 800 mg three times daily + PegIntron + REBETOL for 24 weeks. The subjects were then continued on different regimens based on Treatment Week (TW) 8 through TW24 response-guided therapy (VICTRELIS-RGT). All subjects in this treatment arm were limited to 24 weeks of therapy with VICTRELIS.
Avatar m tn //www.accessdata.fda.gov/drugsatfda_docs/label/2009/103949s5172lbl.pdf REBOTOL reduction protocol. Hgb 2 g/dL decrease in hemoglobin is observed during any 4-week period. Both PegIntron and ribavirin should be permanently discontinued if patients have hemoglobin levels <12 g/dL after this ribavirin dose reduction. Procrit is the other option to raise Hbg either with or without REBRTOL reduction.
Avatar n tn 2 Dose Reduction To prevent treatment failure, the dose of INCIVEK must not be reduced or interrupted. Refer to the respective prescribing information for dose modification of peginterferon alfa and ribavirin [see Warnings and Precautions (5.7)]. http://pi.vrtx.com/files/uspi_telaprevir.pdf If I were you I would contact the pharmacy directly or your doctor or perhaps even vertex and let them know your situation and see if you can get some help with this matter.
Avatar f tn I have heard of smaller people taking less, and I am 5'9'', 160 pounds, but I think my Doctor is prescribing this same amount for most of the people in my home group, that I've talked to.
Avatar f tn How do I store my REBETOL Capsules? Store REBETOL Capsules at room temperature 77°F (25°C). How do I store my REBETOL Oral Solution? Store REBETOL Oral Solution at room temperature 77°F (25°C) or in the refrigerator 36° to 46°F (2° to 8°C).
439539 tn?1233469415 Usually Rebetol is given with PegIntron, and this confused me, because Rebetol is dosed 800 mg for 105 kg, Ribasphere, Copegus and Rebetol are all the same drug, just different names, different manufacturers and different weight based dosages.
439539 tn?1233469415 I checked Schering-Ploughs prescribing information/product information, and there is a table nr. 6 which actually indicates 64 mcg PegIntron for a weight between 40 and 50 kg. This is confusing since they also state that PegIntron should be dosed at 1.5 mcg per kilo. So this is probably where your dosage comes from, although it says that 800 mg ribavirin (Rebetol) is enough for your weight. I would be reluctant though to take less than 1.5 mcg PegIntron per kilo, but that is me.
Avatar m tn http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1804105/ The above study also indicates that lean body weight has an impact on levels in the blood. I'm in my first week of triple tx with Incivek so my morning dose of RBV is taken with the fatty meal for that. It's the evening dose that I am not taking with a fatty snack because of the difference in the 8 hour /12 hour dosing schedule.
Avatar n tn So it is a good thing that you stopped treatment early. HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use INCIVEK safely and effectively. "2.3 Discontinuation of Dosing Patients with inadequate viral response are unlikely to achieve SVR, and may develop treatment-emergent resistance substitutions [see Microbiology (12.4)].
Avatar n tn I understand that is on the prescribing instructions. My take is that it may have to do as much with legal issues as practical. I imagine that if you make sure you're wife doesn't handle the ribavirin (Rebetron), and you wash your hands after touching it, and you use condoms, that the ribavirin shouldn't get transferred to your wife. Should it get transferred to your wife, it could harm the fetus.
Avatar f tn (full prescribing information for Incivek) http://pi.vrtx.com/files/uspi_telaprevir.pdf 14 CLINICAL STUDIES 14.1 Description of Adult Clinical Studies The efficacy and safety of INCIVEK in subjects with genotype 1 chronic hepatitis C were evaluated in three adequate and well-controlled clinical trials: two in treatment-naïve subjects and one in previously treated subjects (relapsers, partial responders, and null responders).
Avatar n tn Don't know how this compares with everyone else but here's what my insurance pays in the US. This covers 4 wks tx and I am taking only 800 mg of Rebetol PEG-INTRON 80MCG KIT $1,256.91 REBETOL 200MG CAPSULE $1,052.
Avatar n tn Here's 2 websites you can go look at for prescribing info. It's very small print and may take a while to peruse to find what you are looking for. Pegasys/Copegus - http://www.rocheusa.com/products/pegasys/index.html Peg-Intron/Rebetol - http://www.rocheusa.com/products/pegasys/index.html I don't think there is any difference in the dosages between the 2 drug co's but didn't know which you are taking. I weighed 120 at start of tx (Oct. 17th) and was prescribed 800 mg of Rebetol daily and .
3159077 tn?1356034731 the ability to detect other genotypes is currently unknown. Analytical sensitivity is 50 IU/mL. Interpretive Information A “detected” result indicates the presence of HCV RNA and is consistent with active infection (acute or chronic). A “not detected” result, on the other hand, is suggestive of the absence of detectable HCV RNA. False negative results might occur due to heparin therapy or HCV RNA levels below the detectable limit of the assay.
Avatar n tn I am wondering if perhaps we are not seeing the right dr. or one who has enough information because so much of what seems to have been discussed on theboards has never been revealed to us? We were just kind f told to start treatment come back in two weeks for tests and Dr. followup and we would go from there. I am sorry I am sounding like such an idiot but I am just beyone confused and overwhelmed. Also... should I be paying this $600.
1225178 tn?1318984204 Bill1954 once posted a website from Schering-Ploughs PEG-Intron prescribing info regarding the effects of food on absorption of ribavirin - may want to check it out: http://www.spfiles.com/pipeg-intron.
Avatar f tn “You can’t compare the results that way, although that’s sometimes difficult for patients, who aren’t aware of the nuances of clinical trials, to understand,” said Dr. Pockros. Physicians should be familiar with both therapies and with prescribing both, said Dr. Kugelmas. “I honestly don’t think that we should be pushing one more than the other or that anyone should prescribe 100% one or the other.
Avatar f tn Most of the members here could oversee treatment and the outcome numbers would be the same and probably better than the average MD prescribing these drugs.
1431734 tn?1421015271 Can you please cite your source information for this? From my perspective, this is incorrect and counselling people that any meal is sufficient to maximize riba absorption would be misleading. The higher the fat content, the higher the absorption factor. It was found that riba absorption increased considerably when increasing the fat content of the meal. So just eating food alone isn't enough. It truly does have to be food with high fat content to maximize ribavirin absorption.
979080 tn?1323437239 From Schering-Ploughs PEG-Intron prescribing info: http://www.spfiles.com/pipeg-intron.pdf Effect of food on absorption of ribavirin: Both AUC and C-MAX increased by seventy percent when Rebetol Capsules were administered with a high fat meal: (841 kcal, 53.8 g fat, 31.6 g protein, and 57.4 g carbohydrate) in a single-dose pharmacokinetic study.
29837 tn?1414538248 Today I intend to put a backgrounder and a link to this information on my home site of 'hep c australasia' . I think it's important that we also get this information to all sites like Janis, Nomads and others. Great letters everyone I'm sure you will make the difference. Lastly can I say to everyone who reads this thread is that your letter/email does not have to be extensive, spell checked or grammatically correct, just to the point.
Avatar n tn Would you have some testimonies, books or adresses to advice us in order to be updated in the comprehension of these sides effects and their potential treatments ? Any information will really be of great help, With my best regards.