Ribavirin dosage hepatitis c

Common Questions and Answers about Ribavirin dosage hepatitis c


Avatar n tn My Pegasys nurse says : about 1 month for interferon and about 70 days for ribavirin. Ribavirin can sometimes be detected in the blood 6 months after completion of tx. I suppose everyone is different. At 6 weeks post, for me, I noticed more saliva. This showed me that the meds were dissipating.
135456 tn?1301441224 a randomized trial.Hepatology. 2007 Oct;46(4):971-81. PMID: 17894303 HgB decline seems a reasonable proxy for concentration, but I've never seen that documented. Testing for effective drug concentration is supposed to happen as part of the early phases of testing so I suppose at this stage the main impetus for such a test would be data showing that patients with similar dosages exhibit a wide range of concentrations. BTW the 14.
Avatar n tn My boyfriend has hepatitis C. I know it can be transmitted through sex. My question is, how long after the first time we had sex should I wait to be tested? I mean, I'm sure that it wouldn't show up immediately.
Avatar f tn Will http://www.hivandhepatitis.com/hepatitis-c/hepatitis-c-topics/hcv-treatment/3583-easl-ribavirin-dose-reduction-and-epo-both-work-for-managing-anemia-in-patients- Reducing the dose of ribavirin and adding erythropoietin are both good options for managing anemia in hepatitis C patients treated with boceprevir (Victrelis) triple therapy, according to study findings presented at the 47th International Liver Congress (EASL 2012) this week in Barcelona.
Avatar n tn This forum is for people who want to gather information regarding Hepatitis C, the treatments of Hepatitis C and support for friends and family of people who have Hepatitis C. Although, some of us do have to take a medicine called Procrit to assist us in keeping our RBC count in a somewhat normal level when we treat our disease with the Hepatitis C medicines. The medicines that we take can sometimes deplete our red blood counts.
Avatar n tn Genotype 1 (more difficult to treat) Approximately 72% of Americans with hepatitis C have genotype 1 Chance of clearing hepatitis C virus is 42-46% Treatment usually lasts for 1 year Ribavirin dosage usually is higher than that required to treat other genotypes Genotype 2 (easier to treat) Approximately 10% of Americans with hepatitis C have genotype 2 Chance of clearing hepatitis C virus is 65-80% Treatment usually lasts for 6 months Ribavirin dosage usually is lower than that required to
Avatar m tn Hello my name is Tyler i am 22 years old I been a heroin addict since 2006, I dropped out of high school due to my sickness, and lost pretty much everything, even my family, in 2010 I got arrested with 4 ounces of heroin and was charged with a a1 felony b felony c felony and a d felony, I was on rikers island jail for 6 months until I pled guilty to a b felony and got released to a drug program called Phoenix house, here I found out I have chronic hepatitis c, I been seeing a doctor in Nassau co
Avatar f tn They specialize in treating diseases or conditions of the digestive system. Hepatitis C effects the liver so they are familiar with hepatitis and its treatment. Swelling of the abdomen is called ascites when it is caused by liver disease. Here is a little info that may help you make an educated guess that you might have ascites. I would say the most important thing is if you also have swelling in your feet, ankles and lower legs (called edema) it is likely you have ascites.
1747881 tn?1546179478ribavirin AUC-12 variability [ Time Frame: steady state (~weeks 9-10) ] [ Designated as safety issue: No ] Demonstrate that concentration-controlled ribavirin dosing can achieve a targeted level of plasma exposure with reduced variability in the steady-state area-under-the-concentration-time curve (AUC0-12) compared with standard weight-based ribavirin dosing Secondary Outcome Measures: •safety - absolute hemoglobin declines [ Time Frame: end of treatment ] [ Designated as safety issue:
Avatar m tn No study has been done where changes in ribavirin dosage has occurred during a trial.) Here is an additional note from the study..."Host and viral factors associated with relapse included high baseline viral load (HCV RNA >800,000 IU/mL), male sex, and using low-dose rather than weight-based ribavirin." It appears that reduced ribavirin it has a large impact on treatment success for someone with your host factors... unfortunately.
Avatar m tn Hi Jose, Interesting link you posted. You're lucky to be diagnosed in the acute stage and to be a genotype two. Most people are diagnosed in the chronic stage for which the standard of care is interferon and ribavirin. I'm not familiar with this topic but I recollect that acutes are usually treated with monotherapy, that is, interferon, and ribavirin is not necessary. Here is another link similar to yours that supports this approach: http://jac.oxfordjournals.
Avatar f tn In combination with peginterferon alfa-2b: Less than 66 kg: 400 mg orally twice a day 66 to 80 kg: 400 mg orally in the morning and 600 mg in the evening 81 to 105 kg: 600 mg orally twice a day Greater than 105 kg: 600 mg orally in the morning and 800 mg in the evening Duration of therapy: -Interferon alpha-naive patients with genotype 1: 48 weeks -Interferon alpha-naive patients with genotype 2 and 3: 24 weeks -Retreatment with peginterferon alfa-2b/ribavirin of prior treatment failures: 48 w
2030686 tn?1351692148 1 Chronic Hepatitis C Monoinfection Adult Patients The recommended dose of COPEGUS tablets is provided in Table 1. The recommended duration of treatment for patients previously untreated with ribavirin and interferon is 24 to 48 weeks. The daily dose of COPEGUS is 800 mg to 1200 mg administered orally in two divided doses. The dose should be individualized to the patient depending on baseline disease characteristics (e.g.
Avatar m tn //www.medhelp.org/posts/Hepatitis-C/Starting-Week-12-on-INC---THEN-WHAT-/show/1637168 .
26471 tn?1211940121 Peginterferon and Ribavirin Dosing and the Utility of Growth Factors Mitchell L. Shiffman, MD Effect of interferon dosing on virologic response It has long been recognized that the ability of interferon to reduce HCV RNA in serum is a dose-dependent process.
Avatar m tn Dear Sir, My son 25 is suffering from heamophilia A since his birth and now since 2004 he got Hep-C (type-3), We did a treatment to cure hep-c with interferon and ribavirin for a complete course of six months and the virus count was only 3,200 at the end of the treatment. Now after 4 years it is positive and the virus (type-3) count is over 7,000,000 and we are again palning to start the treatment.
Avatar f tn The impact of ribavirin exposure on virologic relapse remains controversial in combination therapy with pegylated interferon (Peg-IFN) and ribavirin for patients with chronic hepatitis C (CH-C) genotype 1. The present study was conducted to investigate this. Nine hundred and eighty-four patients with CH-C genotype 1 were enrolled. The drug exposure of each medication was calculated by averaging the dose actually taken.
Avatar m tn Ribavirin priming enhances efficacy of chronic hepatitis C re-treatment in patients who had not responded to previous combination therapy. Ribavirin priming : Oral Ribavirin (1000-1200 mg) alone administered daily for 1 month. http://www.natap.org/2009/AASLD/AASLD_72.
Avatar n tn I don't know why they are telling you to skip Ribavirin doses. You already had to reduce your Ribavirin dosage and you had to stop 5 days early on the Incivek. If it was me, I sure would not skip any Ribavirin doses. And I really do not understand why the treating team is telling you it is okay to skip some doses (wink,wink). The chances for cure are better if a person follows the recommended protocol/regimen/guidelines. Why take the chance. Hang in there. 11 weeks will go fast.
223152 tn?1346981971 Whether you agree or not with pre-dosing, the fact that the PI's work together with interferon and ribavirin is not "old school". Dosage reductions earlier than later with interferon/ribavirin in PI triple therapy result in somewhat lower SVR rates. So clearly the effectiveness of inteferon/ribavirin matters in conjunction with a PI or else it would be PI monotherapy and it's not.
Avatar n tn I just want to post this to say that I have been on my treatment for Hepatitis c virus now for 8 weeks and the doctor told me that my blood does not show any signs of the virus. I am still on the treatment though. I have to finish it I have 4 months to go.
577132 tn?1314270126 26, 2007) — Patients with hepatitis C treated with combination therapy of pegylated interferon and ribavirin had better outcomes when taking a weight-based dosage of ribavirin compared to a flat dosage. This treatment technique also improved the response rates of African American patients, whose outcomes have lagged behind those of Caucasian patients.
Avatar f tn Efficacy and safety of pegylated interferon plus ribavirin in HIV and hepatitis C virus-coinfected patients with advanced immunosuppression. Mira JA, Gutiérrez-Valencia A, Gil Ide L, Merino D, Rivero A, Ríos-Villegas MJ, Delgado M, González-Serrano M, Collado A, Torres-Tortosa M, Omar M, López-Ruz MA, Macías J, Arponen S, Pineda JA. Unidad de Enfermedades Infecciosas, Servicio de Medicina Interna, Hospital Universitario de Valme, Hospital Universitario Virgen del Rocío, Sevilla, Spain.
Avatar n tn Yep, good dectective work. That's the one I was thinking of. In fact, here's a more complete look at the same study: <a href="http://www.natap.org/2004/HCV/041304_02.htm">Treating Non-Responders with Pegasys plus Ribavirin: HALT-C Study</a> (from the paper): "<i>...SVR was adversely affected by reducing the dose of ribavirin during the first 20 weeks of therapy....</i>" Some more stuff: <a href="http://www.natap.org/2004/HCV/030404_02.
Avatar m tn pegasys 1 ampoule 180 micrograms /weeks and ribavirin 4 tablets of day). The HCV RNS test (methods PCR) was 950,000 at the time of the beginning of the treatment ,after three months 3400 and after 6 months was undetectable-negative. The treatment was continued until 11 months, in the last months was suspended because the hematologicaly results decay . The HCV RNS test was repeated in the 13. month (methods PCR) and showed a high value in scale 980,000 orders .
233616 tn?1312790796 Genetic variation of inosine triphosphatase ( ITPA) causing an accumulation of inosine triphosphate (ITP) has been shown to protect patients against ribavirin (RBV)-induced anemia during treatment for chronic hepatitis C infection by genome-wide association study (GWAS). However, the biological mechanism by which this occurs is unknown. Methods: We examined whether ITP can be used by adenosine triphosphatase (ATPase) in human erythrocyte or recombinant human adenylosuccinate synthase (ADSS).
Avatar m tn http://www.medhelp.org/posts/Hepatitis-C/ribavirin-amounts-and-times/show/1588495?
Avatar f tn The pivotal trials that supported approval of the HCV protease inhibitors telaprevir and boceprevir (Victrelis) -- the first direct-acting antiviral agents for hepatitis C treatment -- administered both drugs every 8 hours. But this dosing regimen is inconvenient for patients, which may result in missed doses and reduced effectiveness.