“There is a lack of consensus that opioids are safe and effective
for people with chronic severe non-
cancer pain,” Noble said. “We wanted to look at studies that treated people for six months or longer, given that chronic pain can go on for years. This review includes studies of individuals on opioids for as long as 48 months.”
Patients in the studies had previously tried other treatments like non-opioid medications and physical therapy, but still had considerable pain.