Insulin glargine drug
Common Questions and Answers about Insulin glargine drug
lantus
I would continue to use insulin glargine, a recombinent insulin analogue (Lantus) without concern. This was the recommendation in the British Journal Lancet Vol 1, 374 issue 9649 p511-513 15 August 2009. The media has produced some fear based upon five studies that I have read, and used some statistical manipulation that would have failed me in "statistics one" in the eighth grade. The experimental protocols were pretty crummy.
Examples are insulin zinc suspension, protamine zinc insulin, and the insulin analogues insulin glargine and insulin detemir. The latter two insulins are now the most widely used long-acting insulins.
* Biphasic insulins: mixtures of short-acting and intermediate-acting insulins in different proportions, such as 30/70, 50/50. Examples are NovoMix 30, Humulin M3, Insuman comb and Humalog Mix25.
When I started using 2u Lantus in morning, 2 weeks ago, I'd go low in the late afternoon/early evening, and then my morning sugars would be elevated ... 140s, 150s. So I split the dose: I'm now using 1.5u Lantus AM & 1u Lantus PM. It definitely works better than 2u QD, and I've checked the middle of the night - not a problem. The drug sheet for Lantus doesn't mention BID dosing, but my internet articles do. What are your thoughts, and is Levemir better for BID dosing?
Hi Dawn,
Pizza can be tough to estimate, more because the carb content can vary so much from slice to slice and pizza to pizza. But although I'm just a mom like you, and not a doctor, it sounds like it's not just pizza causing high blood sugar.
You didn't say what sort of long-lasting insulin she's on-- is it Novalin? Or Lantus/glargine? If you haven't tried Lantus (aka glargine) yet, I would strongly recommend talking to your endo about it.
She complained of polidypsia, dry mouth, weight loss. Insulinotherapy was initiated with glargine, ten units at bedtime (glycemic value before aministration was 169) after reiceiving 6 units of aspart imediately (7 pm). Next day a fasting value of 140 mg/dl. Bedtime value (2 hours postprandial ) 269. After 10 U glargine, fasting value 120 mg/dl. Glycemic variation are very important and depend on the thyroid status.
What is your opnion?
Montefiori Medical Center (Bronx, New York) performed an in-depth study of 240 women receiveing Lantus (insulin glargine) during pregnancy. The results were published in the Journal of Reproductive Medicine, April, 2009 (4) 208-10. They found the drug to be well-tolerated and advised continuing the use of Lantus during pregnancy. PubMed has no studies whatsoever that substantiate an adverse affect on pregnancy.
The doctor thinks it is too high and gave Recombinant Insulin Glargine Injection and my mother does 15 unit injection every night. But blood sugar is still like 7.3~8.3 mmol/L before meal and 9-10 mmol/L after meal.
Is this often to see among diabetes type 2 patients?
Can some one give me any advice about how to improve my mother's condition?
Sincerely thanks.
Another question from me:P, i have been reading around latley, and have found many differnt types of insulin,and insulin pumpsm etc. all with there pro's,and cons. If possible, could someone please explain to me the differnt types of insulin, and ways of managing diabeties, and the pros and cons of them.
Have you asked your doctors about the insulin pump. It allows you to set a basal rate of insulin using fast acting insulins (Humalog) for very specific time periods. This will allow you to adjust dosages based on your very specific needs. I have had great success using it. Prior to using the pump I also had difficult time with overnight and morning blood glucose levels. My last A1C was 5.9 it really workds!!!
Lantus (insulin Glargine) is a very SLOW release insulin, a so-called "24-hour" insulin. Because it does not rapidly alter glucose levels it is safe to use when driving. It isn't adviseable to increase the dose of Metformin. Other insulins have the tendency to rapidly (comparatively) alter levels of conscious and situational awareness. It is often prescribed together with Metformin and Glipozide. I would also hazard a guess that weight control is an issue.
com
If you click on the Message board for Lantus glargine insulin, it will bring you to the message board on Lantus. I'm getting ready to take my kitty to the Vet for a dental, so won't have too much more time here. I'll try and get this other link directly to Lantus message board. I give Maggie Lantus every 12 hours,
The links are hard for me to figure out how to post here, but here it is:
http://www.felinediabetes.com/FDMB/viewforum.php?
Sometimes when you have no insurance some of the drug reps, at the dr's offices drop off equipment. especially like bloodsugar meters, all kinds of stuff. not just drug samples. also on T.V. there is the phyzer[spelled wrong] comercial.
This new drug was recently introduced to mimic the role that amylin would normally play in slowing down the rate that sugars leave the stomach. Generally, people who do not produce enough insulin (or any insulin) also do not produce enough amylin.
Unfortunately, it is another injected drug, at meals similar to humalog.
My doctor said she was hesitant at it's launch to prescribe simply based on the fact that she hated to ask her patients to take yet another series of injections.
t make sense why an A1c would be that high if he rarely shows high blood sugars on his monitors. Is he testing regularly? Is he on Lantus/glargine? (That really helped stabilize my daughter.)
Let us know, and good luck with this challenge.
Asacol is not particularly recommended in patients with renal damage, but the issue is that alternative drug therapies may not be as effective or may have varied side effects. Nevertheless it is advisable to replace it with nicotine patches and one or the other newer drug modalities that bypasses the kidneys to prevent it from further damage. It would be best to discuss this with your treating gastroenterologist.
Hope this is helpful.
Take care!
You need further information / evaluation. IF it is high insulin becuase you have insulin resistance then it can be treated with diet, exercise and a drug such as metformin.
If it is high for other reasons, then it would need to be handled medically.
I would expect that it would more likely be becuase of insulin resistance.
Are you normal weight? Do you have any history of diabetes? How old are you?
I have type 2 diabetes, and take metformin, gabapentin, and simvastatin How often should i be testing my blood glucose?
This discussion is related to <a href='/posts/show/612878'>upper leg pain and lower back pain</a>.
It is also a new practice (Joslin diabetes center - one of the world'sleading diabetes management and research centres) to start all persons with diabetes on insulin instead of oral meds.
Glipizide is a drug that makes your pancreas put out more insulin so it can cause lows. It can also make your pancreas burn out faster. So do research this and consider stopping this drug (in coordination with your Dr.)
Metformin does not have this effect. So you can ask your Dr.
Recommended
