http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/500253.html
and did find some info on skin changes ..
"Less common or rare
Depression of the skin at place of injection; thickening of the skin at place of injection; ..." This doesn't mention cellulite directly, but it sounds similar.
The site also has a clear caution to discuss these or any other changes with your doc.
Examples are insulin zinc suspension, protamine zinc insulin, and the insulin analogues insulin glargine and insulin detemir. The latter two insulins are now the most widely used long-acting insulins.
* Biphasic insulins: mixtures of short-acting and intermediate-acting insulins in different proportions, such as 30/70, 50/50. Examples are NovoMix 30, Humulin M3, Insuman comb and Humalog Mix25.
Insulinotherapy was initiated with glargine, ten units at bedtime (glycemic value before aministration was 169) after reiceiving 6 units of aspart imediately (7 pm). Next day a fasting value of 140 mg/dl. Bedtime value (2 hours postprandial ) 269. After 10 U glargine, fasting value 120 mg/dl. Glycemic variation are very important and depend on the thyroid status.
What is your opnion? Is this a temporary glycemic instability, type 2 or type 1 diabetes?
There is a big difference in the action of humalog 50/50 compared to regular. You should really only change your medication with the supervision and guidance of your doctor. Please do discuss this with your doctor.
is aptly named because that is what we try to do with our insulin usage. We are trying to mimic the action of the pancreas in people who don't have diabetes. Their bodies have a low level of background insulin all the time and that's why we take our basal which lasts 24 hours (sometimes not so we split the dose). Then their bodies give off spurts of more insulin when they perceive carbs being eaten.
Humalog is a fast acting insulin. Typically it is taken before meals - up to 15 minutes before (not after) to match the amount of carbs eaten. It's duration of action is 3 - 5 hours, with most of the action in the first 2 hours.
You need to work out a carb:insulin ratio (ie. how much Humalog you need to cover how much carbs/ protein).
If you are going low overnight (how low?), then you need to be taking a lower dose of Humalog with your evening meal.
What time do you eat dinner?
Elevated blood glucose levels are indicative of gestational diabetes, although no one seems to know exactly what causes it. Hormones in the placenta can block the action of the mother's insulin in her body; insulin resistance makes it hard for the mother's body to use insulin, and without enough insulin glucose is turned into energy because it can't leave the body. A high level of blood glucose, called hyperglycemia, requires the baby to work harder.
Cristophe,
It sounds like skipping meals is working for you. And, as long as your blood sugars remain within the target range, thats great. But the insulin you are using was not really designed to be used that way. Mixtard is pre-mixed insulin containing 30% rapid-acting and 70% NPH insulin. It's maximum action is at 2-8 hours after injection. And meals should be timed to coincide with this.
I am assuming that you are referring to your menstrual cycle. For people with diabetes, it is common for blood sugar levels to rise during the premenstrual phase, due to production of hormones that oppose insulin's action. For those who don't have diabetes, the pancreas adjusts by secreting extra insulin, so blood sugar should not rise.
Diabetes is a disease where the body does not proses carbohydrates properly resulting in high blood sugar (BG). lantus is a background insulin, lasts about 24 hours. lantus just keeps you idling along.
When you eat carbs it raises BG as your body digests the food. so you need insulin to lower your BG the same way that food raises BG. When you eat or when your BG is too high you need to take insulin that is faster acting than Lantus.
Yes, surgery is a stress to the body and any form of stress can cause increased blood sugar. The insulin mixes are a very old and not particularly effective type of insulin. If they don't control her blood sugar I would suggest speaking to an endo about putting her on a basal/bolus regimen. (Long-acting insulin once or twice a day and short-acting insulin with the dose to match the food she is actually eating before each meal) That is the standard of care for insulin use.
Great questions, John! You are correct that bolus (fast-acting) insulin does not work evenly. It takes about 15 minutes to begin working and peaks at about 1.5 hours. I pulled out my copy of Using Insulin to look at the chapter on " unused insulin". He does his computations based on a four hour action, rather than a three and divides it into .25 for each of those hours, so at the 2 hour mark you would have 1/2 left (not the 1/3 I use).
http://www.northcoastmed.com/insulin.
Good day walking down the street and accidentally stepped on an insulin syringe, he was without a needle, old and covered with dust, and now I think if I could get HIV, because of the plastic syringe could scratch the foot through the sole of shoes.
- As I understand(after reading in internet) Insulin Resistance is a root cause for this. But we are not sure if it is due to this. If there is Insulin Resistance, the insulin levels in blood should be high. Is there a way to check the levels of Insulin in her body? and confirm Insulin Resistance.
Thank a lot for your help.
I suspect that I may be suffering from insulin resistance or hyperinsulinemia. I have spoken to my GP who said that he doubted this was the case, as I am a normal weight and I don't have elevated blood glucose levels. However I am very hungry, tired and fuzzy headed within less than an hour of eating, and this is immediately (temporarily) relieved by eating a carbohydrate.
I have recently changed to new insulin. I am now taking Levemir in the morning and at night taking Apidra. Since I have changed to this insulin my blood sugar is going upby alot. I was at 176 this morning and within a few hours it was at 296. This has never happened before and I have not changed anything in my eating. Why is it going up so much and how can I make this stop?
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