celebrex and liver disease

Hepatitis C virus (HCV) infection is a major cause of chronic liver disease, which can lead to the development of liver cirrhosis and hepatocellular carcinoma. Recently, the activation of cyclooxygenase-2 (Cox-2) has been implicated in the HCV-associated hepatocellular carcinoma. In this study, we focus on the signaling pathway leading to Cox-2 activation induced by HCV gene expression.

my gi didnt even know the dose to celebrex so i doubt he knows if its good to my liver! im telling yall hes stupid and i need to find a new dr asap!

Which I do know is a sulphamide and I am allergic to sulpha drugs, but in turn, the side effects to Celebrex also mentioned if a rash develops it could be related to liver disease...I was only on the Celebrex for 2 days, so I am still in the dark about the rash. Often at times, I am waking up in the night because of the pain.

Does anyone take celebrex?I started Prozak last week and they want me to take celebrex too. They say my liver can take it, (stage 2 fibrosis). But I am afraid of the NSAIDs in celebrex, any one else taking it? Oh, I am on Methadone too. I am having my first liver biopsy in the morning, so I will find out more about my liver. I am scared to death about it coz I have had so many problems lately.

Heavy drinkers and those with liver disease should at least limit, acetaminophen. Taking the drug while fasting also increases the risk. • Kidney damage. NSAIDs (and acetaminophen to a lesser extent) can damage the kidneys. If you have kidney disease, talk to your doctor about pain reliever safety. Here’s our advice For healthy people who take OTC pain relievers as directed, the risks are relatively small.

If NSAIDs are medically required for the treatment of another medical disorder, a reduced dose should be used for a limited period of time and only by people with stable liver disease. Older women with liver disease seem to be particularly susceptible to the hepatotoxicity of NSAIDs and are advised to avoid NSAIDs altogether. Since NSAIDs may cause salt and water retention people with fluid retention problems such as ascites or leg swelling may suffer worsening of these conditions.

Celebrex is a NSAID... for some it may be ok and others not..largely depends on the condition of your liver and other health factors that the prescribing doctor should be aware of ... here is a past discussion on pain meds. Will http://www.medhelp.org/posts/Hepatitis-C/Article-on-pain-meds/show/1552015?

If NSAIDs are medically required for the treatment of another medical disorder, a reduced dose should be used for a limited period of time and only by people with stable liver disease. Older women with liver disease seem to be particularly susceptible to the hepatotoxicity of NSAIDs and are advised to avoid NSAIDs altogether. Since NSAIDs may cause salt and water retention people with fluid retention problems such as ascites or leg swelling may suffer worsening of these conditions.

I was told today by my awesome insurance company that they will not cover Celebrex. I have been on meloxicam for many years. I'm on day 25 norco free and working with my pain management doctor on non narcotic relief. I thought this maybe a good choice but the insurance company disagreed. Any opinions on arthritis relief options. I have liver issues and I'm tested every 6 months. I also have stenosis, 2 bulging discs and one that has been detached.

I also have Crohn's disease, and I am curently on Remicade and Pentasa. Recently I began having agonizing joint pains. The last time I got Remicade, the pains went aways immediately, however they came back after 3 weeks. I only get the Remicade Infusion once every six weeks, so I am looking into what I can take for the joint pain in between. I am currently trying Tylenol and Tramadol, but they don't work all that well for me.

What analgesics a person can take is dependent on the amount of liver disease you have. Anyone with Stage 0-3 has a fully functioning liver and can take whatever they within dosing limits. If you have cirrhosis (and therefore damaged liver function) you should ONLY take Tylenol/acetaminophen. Other pain killers can cause serious and life-threatening complications in patients with cirrhosis.

Hello fellow Kentuckian the ulcers reflux, gastritis, could be related to your gallbladder issues-which I would suspect because of your functioning % in addition to the other problems. Other possible causes of the ulcers: crohn's disease, peptic ulcer disease,-caused by nonsteriodal antiinflammatory medication usage or H.

I agree with Geminigirl that Celebrex might be a good option for you as it is specifically formulated to help with osteoarthritis pain. Celebrex is COX-2 inhibitor type NSAID and it is linked to heart attack and stroke. If you have high blood pressure, this medicine may not be the right fit even if it is controlled by blood pressure medications. And over time, NSAIDs increase blood pressure so that is a long term side effect that should be considered.

Before my hypo diagnosis, I was on Celebrex (another NSAID) for chronic back pain, and was taken off of it after a liver function test. You could possibly also have a pituitary or hypothalamus issue, but given the ibuprofen and the ease of testing liver function, I'd probably explore that first.

Hi so I have real bad body pain and health issues that cause it. I have found myself buying pain pills Percocet 5/325 and Vic 10s and take 1 sometimes 2 a day. And have been for a little over a month now. However my Dr is now giving me celebrex and it isn't working and I am scared that I am building up a tolerance to pills. Should I go a week and be miserable and then try the celebrex? My body hurts so bad I can't even move some days and I have 5 kids with the youngest being 2 yrs old.

I have been seeing a rheumatologist and she thinks the reason why my hands are constantly falling asleep and swollen and my upper arms are hurting is due to carpal tunnel syndrome coupled with rheumatoid arthritis. I have had tests which have eliminated a pinched nerve. I am taking prednisone, Celebrex, and Plaquenil. My doctor wants me to take Methotrexate, but I don't want to take it as it is very hard on the liver.

What analgesic a person can safely take is dictated by the stage of liver disease, not the treatment drugs or any other factor. Only folks with stage 4 liver disease (cirrhosis) need to be concerned and limited in the analgesics they take. Others with lesser liver disease can use anything that is effective for them. Patients with cirrhosis should ONLY use acetaminophen (Tylenol, Paracetamol) for minor pain relief and fever reduction up to the dosage their hepatologist recommends.

In patients with end-stage liver disease, adverse events from analgesics are frequent, potentially fatal, and often avoidable. Severe complications from analgesia in these patients include hepatic encephalopathy, hepatorenal syndrome, and gastrointestinal bleeding, which can result in substantial morbidity and even death. In general, acetaminophen at reduced dosing is a safe option.

If NSAIDs are medically required for the treatment of another medical disorder, a reduced dose should be used for a limited period of time and only by people with stable liver disease. Older women with liver disease seem to be particularly susceptible to the hepatotoxicity of NSAIDs and are advised to avoid NSAIDs altogether. Since NSAIDs may cause salt and water retention people with fluid retention problems such as ascites or leg swelling may suffer worsening of these conditions.

I have tried Certo and grape juice, tylenol arthritis, Celebrex, and the off brand of something similar. So far I have found that Celebrex works the best, especially when paired with physical exercise. Lifting light weights, doing push-ups on a wall, even just arm circles and stretching. It sounds like it would make it worse, but it actually helps a lot!

i have fibromialgia and arthritis and bone spurs in my neck and shingles should i be taking all this and will the tierdness ever go away?

Once your inflammation dissipates and you stop taking Celebrex everything should return to normal, that is, if you didn't have high morning glucose levels previously. IMHO.

I am on Humaria injections which work very well for me, not that you are that advanced in your disease, but I am....and it is working for me, I was also on Enbrel injections for 5 years before this drug now.

Celebrex and liver disease

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