Lyrica and opioids

Common Questions and Answers about Lyrica and opioids

lyrica

Hello! My Dr prescribed me Lyrica and I have been readin about this drug, but I can't seem to find anything telling me what is in it. Does anyone know the ingredients? I was told it was a non-narcotic drug but then the leaflet says that it can be addictive and do not stop immediately..blah,blah, blah...does anyone know what is in this stuff?
I hope that in time the nerves that were damaged by shingles will heal. Please note, however, Lyrica is filtered through the kidneys and in the beginning of usage of Lyrica I was on the near maximum allowed dosage of Lyrica and it resulted in near kidney shut down as reported to me by my Neptrologist (kidney specialist). It seems then that a managed dosage of Lyrica to match individual tolerance can help in the management of pain. It sure helps me with shingles pain management.
Gabapentin and Neurontin are the same med- you are correct. Neurontin is the brand name. I found Gabapentin and Lyrica to be very similar, but Lyrica is stronger at lower doses. I have tried Cymbalta as well and didn't like it. I had trouble with my GI system. I had diarrhea the whole time I was on it and I became incredibly depressed.
The effects are typically additive in the sense that the opioids act independently of lyrica and they don't interfere metabolically. I've needed to add panadeine or nurofen plus to my daily dose on many a day, when the lyrica isn't enough.
National Center for Injury Prevention and Control Opioids are a large family of biologically active peptides that bind to and activate receptors in humans and can reduce pain and induce euphoria. Humans have a voracious appetite for opioids to the extent that our own brains produce them (eg, endorphins), and many people avidly consume those that are produced by plants or synthesized by factories in our environment.
The best approach is to take a long-acting opioid to cover 80% of your opioid needs, and then use immediate release opioids for 'breakthrough' pain. A typical combination would be oxycontin twice per day plus smaller doses of oxycodone as needed. Then you could add a med for neuropathic pain for the nerve damage; something like gabapentin or Lyrica. Benzodiazepines like Xanax or Valium are not appropriate for your situation-- especially given your history of alcoholism.
I still wake up with anxiety in the morning. I would take a fourth of a pill before work. I also take hydrocodone and 50mg of lyrica in the morning because of 4 back surgeries. They seem to help to settle me down. It's awful waking up every morning and feeling so uneasy and bad. It takes me awhile in the mornings after I take my medication before I feel like getting ready for work. During the day I really don't have anxiety as much as I have awful pressure in my head and headaches.
It has worked well this far along. To me, 3 norco is the equivalent to 2 vicodin to a normal person with normal tolerance. The amount of norco is not based on how it treats my pain, but how much I have grown to tolerate it. If I were to completely stop for a month, 2 vicodin would treat my pain just as 3 norco would. It is unfortunate that I am on this much but like I said some days I can get through with only taking 8 then some days I have to take more.
Right now, our main issue is pain. She has a lot, even with the Lyrica and the Lexepro and Oxycontin. I read a previous post about swimming and physical therapy, and was wondering if the therapy was supposed to make her pain worse than before she started. Often swimming isn't too bad for her, but walking short distances or walking through a store can be excruciating for her.
I am becoming somewhat frustrated with the way a lot of my colleagues practice medicine. Disenchanted, angry would be the other words that could be used. We all get ostensibly that same training and all of us are supposedly in it to help our patients. So, how come have I been getting so many letters lately on my addiction forum from desperate people unable to quit taking the tramadol pills that their own kind doctors have so freely prescribed for them?
He is aware that the last time he combined Lyrica with quetiapine, you had a dangerous reaction. So for him to restart Lyrica while you are taking quetiapine (and a larger dose of it at that) is dangerous and insane as it appears he is expecting a different result from the same combination that almost killed you. You might have better results getting nerve tests from a orthopedic spine specialist or a physiatrist versus a family doctor (GP).
to help clean and cook a meal). He says he *can't live like this* and I try to talk to him and he snaps at me and says he needs to get out and leaves me home alone and I'm stuck. I know it's hard for him, but what can I do? My son moved to China and I am all alone, I am scared and so sad. I have no one else. I was trying to cope and do meditating and breathing (thanks omhome, dalubaba) but it doesn't help my personal situation.
I have a great psychiatrist who is working with my PCP, and I saw a great rheumatologist, but no one has answers, and I've gone through every single thing anyone has told me to try. Lyrica, Cymbalta, Neurontin, Welbutrin, Flexeril... Chiropractic, acupuncture, Reiki meditation, massage therapy... Steroid dose packs relieve some of the pain temporarily, but you can't take those for long and I'm not supposed to take them at all. Elevil at 20 mg has helped a bit.
Any effective Neurotransmitter tests are reserved for pharmaceutical research to develop more psych drugs and anti-depressants, and not for patients diagnostic and treatment purposes. You may also visit the Fibromyalgia Community and do a search there for a thread under:" IWILLDOTHIS " for many helpful natural alternatives to help with Fibromyalgia. This is not intended as a substitute for medical advice. Best wishes.
Two particular ones widely used for pain caused by the nervous system itself are neurontin aka gabapentin and lyrica aka pregabalin. These interfere with the modulation of neural signals, dampening them down. Which is why they help epileptics, and also why they are often effective in treating chronic pain. Unfortunately they also have a list of side effects a mile long, and typically it takes 3-6 months for the body to adapt and for side effects to fade. NNT is around 4 to 6.
There are many different types of medications that cause your body to become physically dependent, including opioids, benzodiazepines such as Ativan, diazepam and lorazepam, and antidepressants. IMPORTANT WARNING — The document below discusses reducing the dose of the medication you are taking as a way to manage your withdrawal symptoms in instances where you no longer have access to your medications.
For neuropathy and other sensations I had relief with both Cymbalta and Lyrica. The only downside to the Lyrica was difficulty with cognition and drowsiness. Savella (milnacipran) is the new medication and it works much the same as Cymbalta...it is an antidepressant. As uk2 mentioned, the patches help with pain as well. My current treatment is with Ultram for both FMS and RSD and Trazadone for sleep. It's much a 'trial and error'...as what works for some may not be right for others.
Will the Opana make me be passing out at work, especially in conjunction with the muscle relaxers and Lyrica? I can't afford this, as I run a business with over 5,000 of employees. I need to be perky and energized, not sedated. Can someone offer the answer, as I may begin using the Opana 120mg per day Monday and stop the Oxycontin 240mg per day. Thank you!
Right now, I am taking Lyrica and it helps to keep my feet and hands from falling asleep and going numb, and a little pain, but it does not help to make me feel "normal" and happy with life. I am not clinically depressed, or else the anti-depressants would make me feel better.
that is what i thought but i was not sure im on a lot of med and they have been uping my lyrica and norco and fentanyl and im on a blood pressure med that dr said would help the nerves and wanted to see if this was somthing i need to talk to dr about the are going to be sending me to a pain management clinic.
However, I have found that they are farther apart versus an everyday affair. I'll be honest with you. Both the Tramadol and Norco are very weak opioids. You may need something stronger...more comparable to morphine. And you may even require break through medication such as percocet. But keep in mind that even upping the strength of the opioids will not get you pain free but it could increase the pain relief an additional 10% or slightly more.
The way he explained it to me was my nerves were angry and they were trying to find their ends that were burnt. He put me on Lyrica and a steroid to help. I have been feeling light headed and feeling not myself since I had all this done. Should I be worried? Should I have the left side done or not. The pain gets so bad I can not stand myself at times. I am on lortab10s for the pain and have been for over 2 years now and they really don't help like they did for the pain.
There are a few other things out there that can help and aren't narcotic or opiate based. I take Lyrica and Soma for chronic neck arthritis and disc degeneration. I find the Lyrica is fairly effective, and the Soma makes me sleepy at night. I'm not happy about being on anything, but it's only been 2 months since I had laser surgery on my neck and I'm still hoping my condition will improve to the point I can get off the meds. I hope I have been a little helpful.
physical therapy, psychotherapy, sympathetic nerve block, medications (including topical analgesic drugs, antiseizure drugs; antidepressants, corticosteroids, and opioids), surgical sympathectomy, spinal cord stimulation, and intrathecal drug pumps. Discuss these with your doctor for proper management. Take care and do keep us posted.
I just wanted to welcome you and also let you know that we have Health Pages (located to the right of your screen), where you can post links and additional treatments and/or other information. I've heard and have been reading about blood clotting problems in people who have both CFS and fibro. CFS/fibro expert, Dr. Jacob Teitelbaum, says that "many infectious organisms do not survive well in the presence of oxygen. These are termed "anaerobic".
Furthermore, at least some of the ACs should be additive with fentanyl. In particular the ACs gabapentin (neurotin) and pregabelin (lyrica) suppress pain by modulation of the pain inhibition subsystem; although GBP and PGB are GABA-mimetic, they seem to modulate predominately through docking with voltage-dependent calcium channels, changing the calcium Ca++ charge within the neurons.
I can't take regular pain pills or anything narcotic because it doesn't agree with me, and I'm at a loss as to how to deal with chronic pain daily. Heat only helps when you're on heat, but the minute you stop using a heating pad, the pain comes right back, and I've tried all the thermal pads, etc. Help!!!
Thank you for suggesting Lyrica, but I've tried Lyrica and some other medication like it and they just made me sleepy. I've tried all kinds of nerve pain relief medication, prescription narcotics, Physical therapy, ice packs, heat packs...etc. etc. The most this Dr. was willing to give me in narcotics is a 10/325 Vicoden. It does seem to help but I still have pain. (I'm def. not expecting to ever be 100% better) but, I am going to see this surgeon and see what he says.
Additionally, a short acting opioid is helpful for breakthrough pain as I have found that even the strongest long acting opioids still leave me with breakthrough pain 2, 3, and sometimes 4-5 times per day. Opioids don't work well for nerve pain, which a good portion of your pain is nerve pain due to the pinched nerve in your spine. Gabapentin (brand name Neurontin), Lyrica, and Cymbalta are great meds to treat nerve pain.
Spinal cord stimulation and intrathecal drug pumps administer drugs directly to spinal fluid so that opioids and local anesthetics can be delivered to pain signaling targets in spinal cord at low doses that for oral use. It decreases side effects and increased drug effectiveness. Take care.
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