In clinical trials, they actually administered 1875 mg of Incivek q8hrs as opposed to 750 mg q8hrs. In that study, the following common adverse events were reported more frequently with the 1875 mg q8h regimen compared to the 750 mg q8h regimen: nausea, headache, diarrhea, decreased appetite, dysgeusia, and vomiting but no life threatening problems were reported.
Incivek should be taken every 7-9 hrs with 20 grams of fat.