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Vioxx trial news

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Avatar n tn Symptons are always have been cold, tired, joint and muscle pain worse in fingers, I took Vioxx before it was removed , high blood pressure , tinnitus, completely deaf over 2,500 cycles in both ears. Hearing aids made no difference. Dentist last month couldn't freeze my gums with 2 needles of Carbocaine. 7mm nodule on thyroid. Blood tests TSH 2.15 ( range .465 to 4.68 ) FT4 11.17 ( range 10 to 28.2 ) Total T3 2.02 ( range .92 to 2.
1658980 tn?1330711550 My study nurse called me this morning to tell me to quit taking the Tegobuvir (GS-9190)as they were pulling it from the study due to uncommon but serious side effects including bleeding issues and severe anemia. Glad I did not have those issues (if I was taking it and not placebo). This is a disappointment to the drug company and also research doctors as the drug looked very promising. Anyone else in a Gilead study that involves the Tegobuvir? You may want to check with your doctor or nurse.
Avatar f tn PRINCETON, N.J., Aug 12, 2010 /PRNewswire via COMTEX News Network/ -- Pharmasset, Inc. (Nasdaq: VRUS) has received fast track designation from the U.S. Food and Drug Administration (FDA) for PSI-7977 for the treatment of chronic hepatitis C virus (HCV) infection. PSI-7977 is an oral uridine nucleotide analog polymerase inhibitor of HCV.
Avatar m tn Methods We used individual patient data from all randomised trials of daily aspirin versus no aspirin with mean duration of scheduled trial treatment of 4 years or longer to determine the effect of allocation to aspirin on risk of cancer death in relation to scheduled duration of trial treatment for gastrointestinal and non-gastrointestinal cancers. In three large UK trials, long-term post-trial follow-up of individual patients was obtained from death certificates and cancer registries.
Avatar m tn Only 375 people are taking part in this BOC trial worldwide,BTW....its the NON-NAIVE trial,meaning its for non or slow responders....i beleive there is a trial being done for naive patients at the same time...if i heard my nurse correctly today. 2.Only 10 people in my trial study hospital are doing the trial.
667078 tn?1316000935 I am in the Amgen 386 trial with Doxil. I had my first follow up CT Scan and all my tumors have shrunk and my CA 125 is down to 49. I am very happy. I am handling the Doxil with no side effects accept fatigue and my white blood cells keep going down to 1400 so I have to delay the Doxil. Iam at stage 4 so this is a miracle to me.
667078 tn?1316000935 CT Scan showed my Cancer has spread. The good news is they think I can get into a clinical trial.
976897 tn?1379167602 It was once believed that the heart contained no stem cells but this was found to be false, they do exist.A peliminary trial involving patients with heart failure who were having bypass surgery. During surgery a piece of right atrium tissue was removed to cultivate approx 2 million stem cells for each patient. 21 patients were in the trial, 14 given stem cells and 7 nothing. The 7 patients showed no change, but all 14 with stem cell therapy showed increase in EF from 30% to 38% after 4 months.
Avatar f tn Wonderful news! You must be sooo relieved to finally have those numbers back up and to be able to start tx. Congrats.
1367233 tn?1316104535 Juttutin, what is your geno? It sounds like the efficacy of PSI-7977 surpasses that of telaprevir and boceprevir by a wide margin, particularly re treatment that does not include INF. I know someone who will be interested in participating in a Phase 3 trial and will watch for info about that. Presumably it won't be possible to do a double blind trial of trial drug and ribovirin versus SOC, since people would know immediately whether or not they're getting INF.
Avatar m tn (ASMB), a clinical-stage biotechnology company advancing a new class of oral therapeutics for the treatment of hepatitis B virus (HBV) infection and novel oral biotherapeutics for disorders associated with the microbiome, today announced initiation of a Phase 1a/1b clinical trial of ABI-H0731, its initial Core protein Allosteric Modifier (CpAM) for the treatment of chronic HBV. The Phase 1a study will assess the safety, tolerability and pharmacokinetics of ABI-H0731 in healthy volunteers.
Avatar f tn Just received the call that let me know that I'm in a 24 week Lambda interferon and ribavairin trial. Meds start the end of next week. I'll be glad to give updates to the experience or answer any questions that I can.
Avatar f tn Have either 8 or 14 weeks left on my trial. Feel great most of the time. This new format has me all mixed up !!!!
980756 tn?1313445908 Hello all..i hope everyone is doing ok! My nurse called me today about a trial to screen for...Danoprevir with ritonavir..has a 50k viral load minmum to get in..been 6 months since last screening which i failed getting in due to only VL only being 7 k...actually its been 7 k the last three screenings arrrg...missed the BOC trial by 3 k ugh..maybe the monsters have been partying since then...question is do i go for it or do i wait for Teleprevir?
1016618 tn?1420553262 and while a 50% reduction is good news, using logarithms, it’s only .30 log reduction. I know you’re in a trial right now; have they offered any indication if you’re receiving the real McCoy, or if you might be getting placebo for the experimental drug? I imagine this is a double blinded study, and even the doctors aren’t aware of which drug you’re getting. Does this reflect the initial first week reduction, or is this a two week report?
Avatar m tn I don't have a firm start date on this trial, but I see there is a person who just finished the 24 hour arm who just got a SVR4. This means an "official" SVR12 is still a few months away. Factor in that these types of results are sometimes saved for liver conferences and one may not see results until even later. At times companies will give out preliminary results, so one does not know when one will see the results revealed, even if they are preliminary or incomplete results.
Avatar m tn //seekingalpha.
149675 tn?1416673133 Great news DragonSlayer - I am so glad when I hear good news about the new drugs!!! It gives us all hope for the future.