simvastatin and liver

Warnings and Precautions Because simvastatin can affect the liver, it is used with caution in people who drink more than a moderate amount of alcohol or have a history of liver disease. Simvastatin is not recommended for people with liver disease or high liver enzymes before treatment begins. Possible Symptoms of Liver Problems Several symptoms can occur in someone who develops liver problems while taking simvastatin.

4 [0027] These cases involve the administration of simvastatin to patients with known Hepatitis B and C, and other causes of liver cirrhosis, mainly alcoholic. All of these patients had normal alphafetoprotein levels and were given simvastatin on a daily basis since their first diagnosis of their liver disease. None of these patients showed an elevation of alphafetoprotein during an observation period.

Statins work in the liver and every commercial I have seen advises not to take if you have liver problems. Zetia works in the intestines. Was the Zetia working? If my memory serves me correctly, MikeS is taking statins and he had a TP. He is far more knowledgeable on the subject than I am and hopefully he will see this post and give his input. Zetia is part of a class of drugs called cholesterol absorption inhibitors.

I have been on 20 mg of simvastatin and 3000 mg niaspan now my ck levels have went from 60 to 295 i could hardly walk .will my levels come down if i lower dose. and reverse damage. i have 12 stents .the rest of my blood work is fine.

Simvastatin is contraindicated in pregnancy and liver disease, according to Wikipedia. I also know that Cresor 40mg is not recommended for Asians. I would like to know why you believe simvastatin and or statin in geneal have ant-hbv activities? Have you heard of cases where statins cause acute liver failure in chronic hbv patients?

was on lipitor for 5 months and switched two weeks ago to simvastatin in hopes of less side effects. just got some blood work done and the liver enzymes are elevated about one and a half times normal. does anyone know if its normal to see a spike in liver enzymes after switching statins or does this mean my body is rejecting the new statin?

5 or 2g 2g can lower healthy bacteria in the stomach of some so probiotics are suggested on the 2g dose of alinia and on simvastatin it is better to check main blood tests, liver tests and creatinine for kidneys every 6 months

Tenofovir and Entecarvir only stop or reverse liver damage. Yes, it could help you get undetectable HBV DNA, but it also worsen your liver cells' infection? Does that even make sense? Because they inhibit HBV from growing, should they lower your virus load, then your liver should become less infected, and have time to repair itself? Alinia seems promising at dose 2g/day for HBeAg negative.

check also who is making the research on simvastatin, and that liver damage has been removed recently, at least here in italy

in New Zealand), which my GP had prescribed me 2 years beforehand to control my cholesterol level. I stopped simvastatin and all fibrillations have disappeared. As I was taking simvastatin, I was in fibrillation 17% of the time; 1 month after I stopped simvastatin, the level was down to 0%. I am now experimenting with alternative cholesterol control methods: Omega 3 gels, ground linseed, charcoal.

But in an in vitro study you have a constant exposure to the drug, which is impossible to achieve in vivo. And the cells used are not the same as regular hepatocytes in human liver, with many differences in gene expression and cellular physiology.

) For the past 20 years, I have avoided NSAIDs, acetaminophens, other pain relievers and muscle relaxants because of their adverse effects to liver and kidneys (personally more significant because my dad had kidney disease). Since cannabidiol inhibits the liver's production of cytochrome P450, I am wondering about switching from simvastatin to pravastatin. That would allow me to try CBD, which appears to have minimal side-effects.

Advicor (lovastatin/niacin extended-release), Simcor (simvastatin/niacin extended-release), and Vytorin (simvastatin/ezetimibe).

As you know, I was on Vytorin for years and went back to Simvastatin about a year ago. I have tested twice since on Simvatstain alone and my numbers have actually dropped a little than during my Vytorin days. I'm only going by the Enhance trial that concudes; "The ENHANCE study enrolled 720 patients who were randomized to receive either Vytorin, or Zocor alone. As an endpoint, investigators looked at the growth of plaques on arterial walls using non-invasive ultrasound imaging.

I am not positive however I thought that if your liver was damaged you should not take any statins to lower your cholesterol. I might be wrong, maybe someone else can help Also normally warnings will come with the medication to say you should not take if you have liver or kidney problems.

Last May, I was diagnosed of Fatty Liver, so I was prescribed to take Godex and Simvastatin. After a month, my blood test rose from 81 U/L to 271 U/L and my SGOT which was previously normal rose to 75 U/L. My intake of simvastatin was immediately stopped due to suspected sensitivity which caused a dramatic liver enzyme elevation. I'm hoping for a decrease in the level of my liver enzymes following the LCD. What bothers me is the Godex. Please advice!

on the contrary studies on these cheap and generic durgs are not funded by drug makers, on the contrary we see stupid doctors without trials or studies saying now that these drugs can make liver damage while it is the opposite. only less than 1% has effects on liver and my question is how many drugs have less than 1% effect on liver..........

-- Long-term use of cholesterol-lowering statins does not increase the risk of liver disease in patients with abnormal liver function, and can actually improve liver function, according to a new study that challenges widespread belief. The researchers also pointed out that this study is the first to show that statins provide a substantially greater cardiovascular benefit in patients with abnormal liver function than in those with normal liver function. The study, published in the Nov.

“If you are unaware that a patient is on simvastatin and you give either boceprevir or telaprevir, the simvastatin level in the blood can go high and patients can develop muscle breakdown,” said Dr. Jensen. http://www.idse.net//ViewArticle.aspx?

They read up on all of her meds called the Dr. he stopped the simvastatin and she is much better now and cont to improve. My husband is on it and has no problems. As with most drugs, they affect people different.

When you are taking statin drugs, periodic monitoring of liver and kidney health is also important. Also if you want to stop the drug, you have to consult the doctor.

Can medications to lower high chlorestorol damage your liver, I have non-alcoholic fatty liver disease now and I am afraid to take statin drugs. How important is my concern. Simvastatin is one in particular.

When discussing the treatment plan 3 years ago, we had asked my husband's hepatologist about it, but reception was lukewarm. My husband was already on simvastatin for high cholesterol, but docs were hesitant to switch him because he was doing well, so I consoled myself to the fact that at least simvastatin seemed the 2nd best statin.

Statins are processed in the liver and so is Incivek. I'm not quite sure if the contrandication is a result of the Incivek elevating the plasma concentration of the statin or the statin lowering exposure and loss of efficacy of the Incivek but it's one or the other.

Simvastatin and liver

Common Questions and Answers about Simvastatin and liver

vytorin