Simvastatin side effects liver
Common Questions and Answers about Simvastatin side effects liver
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Actually, Lipitor is much stronger than Simvastatin and has a much higher incidence of side effects, unless I have missed some new data. According to the links I have Simvastatin is the safest statin on the market.
Effective in June 2011 the FDA recommends limiting the dose of simvastatin to a maximum dose of 40 mg, with the exception of patients already taking simvastatin 80 mg daily for a period of greater than 12 months who have not developed any myalgia side effects. The FDA make this restriction because at the highest dose of simvastatin 80 mg daily the incidence of serious myopathy was higher than using other available statins.
All of my cholesterol-related numbers are in a healthy range, and I have never experienced any serious side effects (e.g., muscle weakness, kidney and liver impairment, etc.). I have, however, had trouble sleeping for the past several years (perhaps caused by simvastatin, perhaps not). More importantly, I have been experiencing back pain for the past few months and would like to try CBD. I am down to sleep a few hours a night.
was on lipitor for 5 months and switched two weeks ago to simvastatin in hopes of less side effects. just got some blood work done and the liver enzymes are elevated about one and a half times normal. does anyone know if its normal to see a spike in liver enzymes after switching statins or does this mean my body is rejecting the new statin?
• An increase in liver enzymes
• Hepatitis, which is an inflammation of the liver that can cause tiredness or a general feeling of illness
• Jaundice, or a yellowing of the skin or eyes that can occur due to liver damage
• A fatty change in the liver
• Cirrhosis
• Hepatoma, which is a type of liver cancer.
Increases in liver enzymes occur in about 1 percent of people taking simvastatin. The other liver problems mentioned occur in less than 1 percent of people.
Have you been on Simvastatin long? Side effects normally do not start after 90 days of use. Your other drugs may be causing the problem, especially the Neurontin which has concentration problems as a main side effect which can get worse the longer you take it.
If you feel it is the Simvastatin, you can always ask your doctor about going off of it for a short while to see if it improves. This is a rare side effect of Simvastatin so I would look elsewhere for the problem.
I would recommend asking your Dr or pharmacist if these are possible side effects. There could be another reason why you're gaining weight and your BP is up. You should'nt have any side effects from stopping this med but, your Dr put you on it for a reason. I take it you had high cholesterol numbers? See your Dr before you quit taking it. That's just my suggestion.
was on liptor 20 but not liking it so two weeks ago started simvastatin 30 to see if more tolerable b/c my research said it had the lowest rate of side effects of the potent statins. numbers were normal on 20 lipitor but are now alt 68 ast 54.
Hello,
If you Google for ' ramipril side effects ' or simvastatin side effects ' you will get more details. Ramipril has been indicated to cause sexual problems, but both these drugs can affect liver function and in turn affect sexual performance.Further more, statin drugs can cause muscle weakness and may lead to a drop in overall energy level.
using simvastatin it is necessary to keep checking alt/ast before and after use of it, although extremely rare it may happen that sim increases alt/ast and if increase is too much (alt>100) it may be necessary to stop it
using vitamin d, although extremely rare it is better to check serum calcium every 3-4 month together with vitamin d 25oh, the max range of vit d is 100ng/ml
if expensive you can skip calcium and just check vit D after 6 months
I have not taken simavastatin for 4 days and I am still suffering panic attacks mainly morning and the evening. I read somewhere it takes 10 days to get out of the liver.
Hi,
If you check the PDr (physician's desk reference) or any literature on statins -- you will find that part of the spectrum of side effects is liver damage, hepatic failure and death. So, please don't buy into any information to the contrary, i.e. that it can now aid in the treatment of the very organ that it is widely known to destroy.
Good luck and God bless.
hey Jeff.. That is a could subject you have brought up.
It will be nice to find a pharmacy that sells good quality meds.. I know in the US it is impossible to test the medication from a third party. Other countries you can..
I have heard of people buying Chinese Baraclude for dirt cheap, and other drugs.. But I am very concerned not be sold something that can poison me. That is the only thing why I did not try Alinia.. It is a very good effective drug against HepB..
[0010] Use of simvastatin in the prevention of malignant diseases, especially liver cancer or hepatocellular carcinoma, has been previously unknown. According to the present invention, by administering simvastatin to patients with an existing liver condition, and by monitoring the level of alphafetoprotein, a liver tumor marker, the formation of liver cancer can be prevented.
Simvastatin is contraindicated in pregnancy and liver disease, according to Wikipedia. I also know that Cresor 40mg is not recommended for Asians. I would like to know why you believe simvastatin and or statin in geneal have ant-hbv activities? Have you heard of cases where statins cause acute liver failure in chronic hbv patients?
Thank you for your suggestion. I looked up the side effects of Simvastatin today and many side effects sound like what my mother is complaining about. I told her to stop taking it for a few days to see what happens. I agree, her doctor is questionable. This is my first time using a forum and I'm finding it to be a lot of help. Thank you...
s more of which one your body will tolerate the best. Different brands seem to show different side effects in many people. Lipitor in some women have produced breast pains or enlargement and even the manufacturers cannot explain that one. Still, I suppose it's cheaper than plastic surgery. Some statins cause abdominal pains in some people, or nausea or serious muscle cramps and even damage.
I take Simvastatin with no side effects, and have for several years, and so does my husband, also no problems. It's done an excellent job of lowering both our cholesterols.
now she is asking me to research about clevudine revovir and mushroom in tivoli if they are effective and what are their side effects.. For those who have the same illnesses as my aunt have, please do give us informations advices tips on how can we treat these illnesses. thank you to whoever would reply. God bless.
curious if stef2011 or studyforhope or StephenCastlecrag know whether simvastatin by itself can reduce viral load? I've read about the effects in conjunction with NUCS but I'm curious if sim is effective alone.
Usually diet and exercise is the best first place to start, but with an LDL this high I would probably recommend starting a cholesterol lowering medication as well, such as a statin (e.g. atorvastatin, simvastatin). All medications have potential side effects, but the statins are relatively well tolerated by most people and your doctor should be watching for any dangerous side effects (which are rare).
Millions of people have taken SIM safely. While there are rare adverse effects, these side–effects are well delineated. Moreover, it is even possible that SIM may become useful in the treatment of portal hypertension. Abraldes et al have extensively investigated SIM as an agent to treat portal hypertension (Zafra et al., 2004). They recently reported a 30-day double-blind randomized controlled trial using 20 – 40 mg/day of SIM.
The study found that the patients on simvastatin achieved the target LDL level of less than 130, more than those on pravastatin (65 percent on simvastatin versus 35 percent on pravastatin). The most common side effects of the statins in general are nausea, gas, and upset stomach. Less common are headache, dizziness, rash, sleep disturbances, muscle pain, cramps, or weakness.
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