Ribavirin storage

Common Questions and Answers about Ribavirin storage


Avatar f tn Another person on this forum had this issue with Sovaldi and Olysio, and SVRd, it isn't ideal, but it didn't affect his result. Which month is it? Your first?
Avatar n tn How do you travel with ribavirin and peg-intran which have to be refrigerated...am to new to this whole process.
29837 tn?1414538248 Be sure your Ribavirin is in a container with your name on it or it may be confiscated by Customs, especially in third world countries. It may also be a good idea to contact the American Consulate in that country (or better yet before you leave this country) and ask about their rules/laws as far as bringing pills and syringes in their country, as some foreign countries (like Turkey) have very strict drug laws.
422881 tn?1257607179 Yes most of us take 180mcg. I don't know the answer as to why your doc gave you 150mcg. The injections, yes, go in the refrigerator and the riba room temp. My riba wasn't in with the injections in the cooler - they were separate. I don't know if that makes a difference that yours were in the cooler - doubt it, cause they wouldn't freeze in that thing, but dunno for sure. My post will bump you back up and hopefully someone that has more answers will see your post.
Avatar f tn Ribavirin should be refrigerated at 2-8 C (36-46 F). -------------------------------------------------------------------------------------------- http://www.fda.gov/downloads/Drugs/DrugSafety/ucm088576.pdf How should I store COPEGUS? • Store COPEGUS tablets between 59°F and 86°F (15°C and 30°C). • Keep the bottle tightly closed.
Avatar m tn I agree with Hector, no problem... "Proper storage of ribavirin capsules: Store ribavirin capsules at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep ribavirin capsules out of the reach of children and away from pets. http://www.drugs.com/cdi/ribavirin-capsules.
1225178 tn?1318984204 There’s a condition known as ‘porfiria cutanea tarda’ (PCT) that is heavily associated with HCV. It involves iron storage issues, and can be resolved rather readily by a process known as phlebotomy, or bloodletting. It presents as blisters on areas of skin that are exposed to sunlight; often arms, hands, face, chest, etc. It might be a good idea to avoid direct sunlight until this can be either ruled out or dealt with somehow; I think covering up won’t hurt, and might help a whole bunch.
233616 tn?1312790796 In comparison with corresponding plasma values of ribavirin following a high-purine meal, Cmax, AUC0-144 and AUC0-∞ of ribavirin following a low-purine meal were 136% (90% confidence internal [CI]: 120%-155%), 134% (90% CI: 118%-153%), and 139% (90% CI: 120%-159%), respectively. This study indicates that dietary purines have an effect on ribavirin absorption. Dosage regimens of ribavirin might need to be adjusted according to the purine content of the meal.
Avatar m tn Best wishes for successful treatment and achieving SVR The heat concern for meds is mainly related to storage. FYI Anyone interested in reviewing general medication storage recommendations. Storing medicine safely http://www.nlm.nih.gov/medlineplus/ency/article/007189.htm excerpts Many people store their medications in the bathroom..
Avatar f tn on the box. I am worried that the medicince is not working because of the wrong storage x 5 days. Any advice?
Avatar m tn The best thing to do is phone your Pegasys provider and discuss your situation with the pharmacist, preferably a Roche specialist. Different interferons may have different storage requirements. Interestingly, my own Roche-associated pharmacist was more concerned about freezing than leaving meds at room temperature. (He warned me to never freeze the peginterferon, even for a second.
9369350 tn?1403517919 Storage and Handling Victrelis Capsules should be refrigerated at 2–8°C (36–46°F) until dispensed. Avoid exposure to excessive heat. For patient use, refrigerated capsules of Victrelis can remain stable until the expiration date printed on the label. Victrelis can also be stored at room temperature up to 25°C (77°F) for 3 months. Keep container tightly closed. http://www.drugs.com/pro/victrelis.
Avatar f tn Rare macro and microvesicular steatosis is seen. No increase in iron storage. The GI doctor has recommended that we check his lab work every 6 months to monitor his progress and not do treatment at this time. He says that there are alot of new drugs coming out in 2012 that will be better than what there is today. My questions are: is it better to treat now while the effects of the virus are minimal?
1794638 tn?1345158661 “Proper storage of Ribavirin: Store Ribavirin between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Ribavirin out of the reach of children and away from pets.” http://www.drugs.com/cdi/ribavirin.html Ribavirin has a long half life; as long as you get your daily dosage in, it probably doesn’t make much difference how you balance the time out in terms of hours.
Avatar m tn I assume your doctor has performed iron studies? It’s one thing to have high iron storage problems in hepatic tissue, but another if the blood is deficient. I’m not personally familiar with epo; I’ve never required it myself. I’ve heard anecdotal reports from other members here that have taken up to 80,000 units/week; but that was prior to the U.S. FDA black box warning issued in ’07: http://www.medpagetoday.
Avatar m tn I don't really know much about the zone diet either, but I would think as long as it's balanced, and you're getting enough fat to absorb the ribavirin, it should be fine. Sorry to hear you failed 3 treatments! That sounds rough. Are you planning to try again with Telaprevir or something?
140622 tn?1190102529 We had a fellow in here who had Thalessemia (not sure of spelling) and so had anemia before he started. He went through hell but was a genotype 2 but did complete treatment. Unfortunately (and it broke our hearts and his) after the nightmare he suffered thru (hemo of 6 was common even with procrit) he relapsed. I don't know if a doctor would prescribe procrit in advance - however it does a great job for most of us, it's a miracle drug. Without it I could NOT have completed treatment. NO way.
Avatar m tn Route Strength Proprietary Name Applicant 076192 AB No RIBAVIRIN CAPSULE; ORAL 200MG RIBAVIRIN SANDOZ -------------------------------------------------------------------------------- 076277 AB No RIBAVIRIN CAPSULE; ORAL 200MG RIBAVIRIN TEVA -------------------------------------------------------------------------------- 077224 AB No RIBAVIRIN CAPSULE; ORAL 200MG RIBAVIRIN ZYDUS PHARMS USA --------------------------------------------------------
Avatar n tn Hello, Friends, After 1 week without ribavirin, I'm back up to Hgb 8.5 as of yesterday. My iron levels were checked, and indeed I have depleted my iron reserves; I am to start 325 mg iron supplement am and pm. Lesson here: Procrit may eventually need iron supplementation to work, so your iron levelsshould be checked if the Procrit stops or isn't working. My next check is on Mon.8/18. Hope to resume riba next Monday... maybe gradually increasing dose back up to "normal".
Avatar m tn Although hepatic iron is usually only mildly elevated in hepatitis C virus, iron overload is associated with more advanced disease, nonresponse to interferon monotherapy, and increased risk of hepatocellular carcinoma. Iron status does not predict response to interferon and ribavirin combination therapy. Most studies indicate that HFE mutations are associated with increased iron stores and advanced fibrosis. Iron depletion therapy may delay disease progression.
1431734 tn?1421015271 //www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1804105 "The component of the final population pharmacokinetic model that describes the absorption phase is complex. Although a standard meal did not affect ribavirin bioavailability (F1), administration of ribavirin with a high-fat meal increased bioavailability by 46% relative to the fasting state. A high-fat meal prolonged the duration of the zero-order input part of the absorption model, with D1 increasing from 0.
Avatar f tn Hello Vesnic, and welcome to the discussion group. Yes, assuming he is currently using pegylated interferon and ribavirin, he has roughly 70% odds of successful, permanent clinical resolution. The term used is ‘SVR’, or Sustained Viral Response. This occurs when the patient completes his prescribed treatment with undetectable viral status; then six months after treatment if the virus is still undetectable it will not return.
3203287 tn?1346460234 In two of the clinical trials they had arms that contained no Riba, just Incivek and Interferon. The arms without Riba had significantly lower SVR rates. Reducing Riba may be the initial step when the Hgb drops below 10, but I don't think I have ever heard of going from 1200 mg to 400 mg in one fell swoop at day 15. And most people on the forum who had Hgb drops reduced Riba some and used Procrit. Many also had transfusions. I don't know if you have ever had anemia before.
Avatar f tn and that is when the Ribavirin (and to some extent the new DADs) desrtoy the red blood cell too soon and faster than the bone marrow can make them.Also INF can suppress bone marrow production of red cells..so it can be a bit of a double whammy. That is much different than having a low iron storage.. and hemolytic anemia can not be treated or raised by eating iron enriched foods or taking an iron supplement...(which can do more harm than good ..as James mentioned) Not everyone on tx.
Avatar f tn Whether you need to avoid foods rich in iron depends on if you have iron overload or iron metabolism problems. If you are not cirrhotic and you do not have any iron metabolism or storage problems, then you do not need to avoid foods high in iron. You can find out if you have iron metabolism problems through a few blood tests which your doctor can order. Ask your doctor to check you for iron overload or iron metabolism problems.
Avatar m tn Still - there are alot of new studies that can help us up the odds a bit. Knowledge is a very important thing when fighting this disease. If you take the ribavirin with fat it will help with the absorption rate. I always took it with breakfast at 7am and dinner at 7pm so it was 12 hours apart and with a nice meal with fat. Even when I didn't feel well I always made sure to have SOMETHING with it even if it was ice cream (which unfortunately is one of the best foods for treatment).
1508600 tn?1289925850 Some folks with HCV have iron storage problems; that group needs to closely monitor their iron intake to protect their liver from damage. If your doctor has reviewed your lab results and determined that you require supplemental iron, then by all means, do as he says. I can’t recall if you’re currently in treatment for your HCV or not; if so, the ribavirin can cause additional anemia; it’s a good thing your doctor is on top of all this.
Avatar n tn however, I believe that HCV patients often tend to have iron storage problems. An ‘iron studies’ test should yield enough info for the doctor to determine if supplemental iron is necessary. Iron is an essential trace mineral; and is required to transport oxygen to tissue. More info on these tests is available from lab tests online: http://labtestsonline.org/understanding/analytes/iron/glance.
Avatar m tn Furthermore, iron overload may be responsible for hepatitis C resistance to ribavirin and interferon (IFN). The serum ferritin level appears to influence the type of IFN response achieved. In one study, those patients with hepatitis B infection and a serum ferritin level > 300 ng/mL failed to respond to IFN in 93% of the cases studied.