Ribavirin peg intron

Common Questions and Answers about Ribavirin peg intron

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29837 tn?1414538248 NM283 is a newer drug that combined with Peg Intron and Ribavirin is supposed to act on non-responders like myself. Naturally, I'm a little hesitant to enroll in this trial without further information, since I've failed three brutal treatments already. Has anyone gone through or anyone know someone who's gone through this NM238 clinical trial? If so, has there been any success or just more torture? Any info will be greatly appreciated.
Avatar n tn Fewere symtoms, best results? Pegasys is a newer med but my doc wants to put me on Peg-intron?????? All that I've read, everyone prefers Pegasys....Anyone have a good doc in S.Fla?
Avatar m tn My experience was that Pegasys was by far and away easier to tolerate than was Peg-Intron and I took a bigger dose of ribavirin with Pegasys than I did with Peg-Intron. I treated with Peg-Intron on my second try and I cleared late probably around week 24. I knew that I shouldn't stop at week 53 but I was so beat up I just threw in the towel and prayed. I relapsed is less than 3 weeks and started on Pegasys 5 weeks later.
Avatar n tn I wanted to try Pegasys, but the Dr who runs the program at Kaizer in the portland area, has said that pegasys is used in people under 75Kg or about 165Lbs and Peg-Intron is more effective in people over 75Kg or 165Lbs. Have any of you been told this? I have searched all over the internet and cannot find anything to backup his thinking. Any help would be greatly appreciated.
276730 tn?1327966546 I have only been on Pegasys but I was told that PegIntron has more sides, but that was just hearsay..I thought you weren't starting tx till january, or am I confused?
Avatar n tn Starting the HepC Tx in Aug. I have done alot of research and PREFER to use Pegasys(Roche) over Peg Intron. My info says the side effects are less SVR is better with Pegasys; that, coupled with the fact that there is a class action lawsuit against Scherring-Plough because of PegIntron..well.... My doctor wants me to use Peg Intron because Pegasys is NOT weight based. However, Pegasys dosage CAN be configured to the patient and viral response as well as weight, with a little simple math!!
442340 tn?1326821017 Hi All, Well it looks like my docs office wants to treat me with Peg Intron (80 mg) and Ribaviron 1000mg tablets. She said the Peg Intron in her experience causes a more "predictable" decline in red blood cells than pegasys. I am only 110 lbs, so she said because it is weight based too, that is better for me. Any thoughts on Pegasys vs. Peg Intron? My stats again - female, mid 20s, type 3a, VL 950,000. I have been infected since birth (my mom was HCV). Thanks!
Avatar n tn In 2000, I tried Intron A/Ribaviron combination, Schering's predecessor to Peg-Intron. I lasted 7 weeks and had to stop due to severe sides. Before trying treatment again, I found research (posted on this site at some point) showing Pegasys had fewer sides and may better for type 1's. Also, some folks here reported fewer sides and better quality of life. My GI was cool either way.
Avatar f tn Hi my first time on here I am starting my peg-intron an ribavirin on saturday. When I take the 4 pills in the morning how are the sides? I am suppose to work?
Avatar n tn The ribavirin warnings say in effect, "no getting pregnant or getting someone pregnant for at least 6 months after tx." I don't think it's the DNA technically but rather the mRNA that's the problem. Ribavirin is an RNA mutagen.
Avatar n tn recommend her 80 microgram dose of peg-intron injections with 400mg Virex capsulse. While I have read on Peg-intron literature that its dose is given by weight. For monotherapy use 0.5 microgram/kg/week. For combination therapy 1.5 microgram/kg/week...i think my mother case is combination therapy (injections + capsules).And for 60 kg weight injection dose should be 100 micrograms. Please advise.
Avatar f tn 2 weeks ago I started on Peg Intron once a week and Infergen 3 times a week. Is anyone currently on this cocktail? Please respond if you are.
Avatar n tn Anecdotally, people seem to describe the side effects of Pegasys as being not so rough as Peg-intron, but since everyone reacts to these meds a little differently I think it's a tough one to call. If you travel a lot Peg-intron might be the better choice because you can get it in powder form and don't have to worry about refrigeration. I travel a lot though and did Pegasys without any problems. I've heard a lot of people complain about the Peg-intron redi-pen delivery system.
Avatar n tn I am interested in moving my peg-intron shot night from Friday to Sunday now that my kiddos will be back in school. My doc recommended doing it over a couple of weeks (i.e. go to saturday one week and then sunday the next). This sounds reasonable to me but just wanted to see if you guys have been any experience with doing this or have any advice. I guess my biggest concern is that I don't want to risk my peg levels getting too low. Many thanks.
Avatar n tn I've treated 7 times with Reg-Intron-A, Infergen, Pegasys, Peg-Intron, Maintenance and a combination of Infergen-Actimmune-Riba. All at different times, of course! Anyhow, this is what happened to me.
163305 tn?1333672171 I have heard that the sx for peg-intron are worse than pegasys. There is a thread from last week discussing this very topic. You might check the archives for a quick answer.
442340 tn?1326821017 I got two letters today, one saying that I am denied Peg-Intron beacuse I did not try pegasys. And the second said I was denied Ribaviron because that is only approved for people with hep C using peg-intron or pegasys with geno 2 or 3. HELLO INSURANCE CO....I'm HCV and geno 3!!!! SOOOO FRUSTRATING! Sorry, needed to vent. Any advice would be great! Thanks!
Avatar n tn I CALLED TO REORDER MY MONTHLY SUPPLY OF PEG-INTRON AND RIBAVIRIN TODAY, AND THEY TELL ME THE MAIN OFFICE THAT HAS MY PEG-INTRON IS IN NEW ORLEANS AND THEY MAY NOT BE ABLE TO DELIVER IT ON TIME. I AM INTO WEEK 12 OF TREATMENT. WHAT TO DO? IS IT OKAY TO STOP TREATMENT AND WAIT FOR MY MEDS TO COME? I KNOW FOR A FACT THE PHARMACISTS HERE DON'T CARRY PEG-INTRON IN STOCK. SHOULD I JUST DO MY NEXT INJECTION ON THE DAY THE MEDS DO GET HERE?
Avatar n tn I was just informed yesterday that I am a non-reponder after 12 weeks of PEG Intron treatment. I am enrolled in a clinical trial for Peg Intron and needed to have a 2 log drop in my viral load, mine is .93. When I started treatment, my load was 1,267,442 IU, dropped to 92,854 WK2; elevated to 641,599 WK4 and I am now at 149,000 WK12. I am told this is considered non-responsive and have a meeting with a nurse and hep doc tomorrow.
Avatar n tn This is why ppl usually get more sides with PEG-Intron. P.S.
Avatar m tn I'm glad that this post about rage/emotions was open today. I have a few concerns of my own regarding this subject...my husband is now on daily infergen and riba (clinical trial). While he was on pegysus/riba he definitely experienced raging moods, a temper he rarely had before and an abrubtness about him. All new to his personality. This time around he seemed to be handling things well into his 5th week (35/336.) About that time his mood started to change.
Avatar n tn My doc put me on Peg-Intron and Ribavirin. Apparently only Schering Plough, Inc. makes Peg-Intron. They required me to obtain a code number from them which I did. Then the nightmare began. I was able to obtain a 1 month supply of Peg-Intron from Wal-Mart after considerable difficulty trying 5 or 6 other local pharmacies. To remedy this problem I tried to order the Peg-Intron from Merck Medco, my medicine insurer.
26471 tn?1211940121 Mark Sulkowski of Johns Hopkins may have been the first guy to double Peg-Intron. Cecil made it popular. Sulkowski is probably more revered. Lots of heavy hitters out there are ignoring FDA recommended protocol and proving that novel therapies work for a significant number of nonresponders. One of the big things emerging is extended dosing for genotype 1.
Avatar f tn If taking Vic 3xtx do u get to pick Pegasus or peg intron Or do u have no choice? Cause another thread about int fevers said that a study done in Italy showed better results with Pegasus Thank u!
Avatar n tn My father was diagnosed w/Hep C and began treatment 7 months ago. After being on Peg-Intron and Ribavirin for 5 & 1/2 months, he was told that his liver enzymes were back to normal and only continue the treatment to complete a 6 month course. He was initially told that he would have to be on this treatment for 10 months. He has now been off of his interferon for 4 weeks and received a call from the Dr. telling him that his bloodwork came back showing elevated liver enzymes again.
Avatar f tn I've treated with the Peg-Intron twice. The second time I also was on daily reg. Intron-A with it. I'm on my second time with Infergen, but this time I'm also on Actimmune(Gamma) with it. Take care, God Bless.
314554 tn?1337457719 I realize this is a frequently addressed topic – but I am trying to get this straight in my mind; so, here goes: Given: 1) Due to it's longer and branched-chain PEG, Pegasys has a half-life ("terminal elimination") of 50-80 hours. 2) Whereas, due to it's shorter and linear-chain PEG, Peg Intron has a half-life of 30-50 hours. (Note that NPIA or non-pegylated interferon alfa has a half-life of only 3-5 hours.
Avatar n tn Is there a place in San Francisco area where I can donate ( I know it will be illegal for me to sell my unused medication so I am willing to donate rather then dump down the drain) unused peg intron and ribavirin capsules ? I have 3 shots / boxes of 120ug/0.5ml peg intron 2003 exp date and approx 100 ribavirin capsules. The peg is sealed so I would imagine there is no problem, Riba capsules are in open bottle so may be there is a prolem with them.
Avatar n tn I did both but relapsed w/Peg-Intron. But I cleared late and stopped at 53 weeks. Also ribavirin dose was 800 mg. and I think that is why I cleared with Pegasys & 1000 mg. ribavirin- but I did 73 weeks too.