Ribavirin oral solution

Common Questions and Answers about Ribavirin oral solution

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2030686 tn?1351692148 Store ribavirin tablets and capsules at room temperature and away from excess heat and moisture (not in the bathroom). Store ribavirin oral solution in the refrigerator or at room temperature. Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication. It seems like my other two friends have you covered on anything else, good luck and Hi Advocate and B.
Avatar f tn Store ribavirin tablets and capsules at room temperature and away from excess heat and moisture (not in the bathroom). Store ribavirin oral solution in the refrigerator or at room temperature. Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication. -------------------------------------------------------------------------------------- http://www.medicinenet.com/ribavirin/article.
Avatar f tn In combination with peginterferon alfa-2b: Less than 66 kg: 400 mg orally twice a day 66 to 80 kg: 400 mg orally in the morning and 600 mg in the evening 81 to 105 kg: 600 mg orally twice a day Greater than 105 kg: 600 mg orally in the morning and 800 mg in the evening Duration of therapy: -Interferon alpha-naive patients with genotype 1: 48 weeks -Interferon alpha-naive patients with genotype 2 and 3: 24 weeks -Retreatment with peginterferon alfa-2b/ribavirin of prior treatment failures: 48 w
233616 tn?1312790796 Twenty healthy participants were enrolled in a randomized, 2-period crossover study. Participants were administered a single 600-mg oral dose of ribavirin after either a high-purine meal or a low-purine meal. Serial blood samples were collected predose and over 144 hours after dosing. Ribavirin concentrations were measured by liquid chromatography/tandem mass spectrometry.
Avatar f tn Effect of Food on Absorption of Ribavirin Bioavailability of a single oral dose of ribavirin was increased by co-administration with a high-fat meal. The absorption was slowed (Tmax was doubled) and the AUC0-192h and Cmax increased by 42% and 66%, respectively, when COPEGUS was taken with a high-fat meal compared with fasting conditions [see Dosage and Administration (2.1) and Patient Counseling Information (17)]. " http://www.accessdata.fda.
Avatar f tn Anemia The primary toxicity of Ribavirin is hemolytic anemia, which was observed in approximately 13% of all Ribavirin/peginterferon alfa-2a- treated subjects in clinical trials. Anemia associated with Ribavirin occurs within 1 to 2 weeks of initiation of therapy. Because the initial drop in hemoglobin may be significant, it is advised that hemoglobin or hematocrit be obtained pretreatment and at week 2 and week 4 of therapy or more frequently if clinically indicated.
Avatar m tn New data announced today by Vertex Pharmaceuticals Incorporated VRTX show that VX-950, an investigational oral hepatitis C virus (HCV) protease inhibitor, dosed in combination with pegylated interferon alfa-2a (Pegasys(R); peg-IFN), achieved a rapid and dramatic reduction in plasma viral RNA levels in patients with chronic genotype 1 HCV infection.
Avatar f tn It's Debio-025 oral solution used in combination with Pegasys and Ribavirin (if you're placed in that group that gets all 3 drugs).
Avatar m tn Both Ribavirin and Interferon can cause serious eye problems: http://www.drugs.com/sfx/ribavirin-side-effects.html Adverse Reactions: Ribavirin: Ocular "Ocular side effects associated with oral ribavirin in combination with peginterferon alfa-2a, peginterferon alfa-2b, or interferon alfa-2b have included blurred vision (up to 6%). Corneal ulcer has been reported in less than 1% of patients treated with peginterferon alfa-2a alone or in combination with ribavirin tablets.
Avatar f tn Store ribavirin oral solution in the refrigerator or at room temperature. Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication. http://www.nlm.nih.gov/medlineplus/druginfo/meds/a605018.
Avatar m tn Are you completely finished with all Hep C treatment, including Interferon and Ribavirin? I developed a rash at week 10 or so. Benadryl and over the counter Cortizone cream were useless for it. What did work for me was Hydroxyzine 50 mg every 6 hours, Fluocinonide ointment, and Clobetesol soln. They are all prescription.
Avatar m tn "Does this mean, the medicines are not working as well." -------------------------------------------- No, it does not mean the medicines are not working. See explanations below. "Did anyone experience this on treatment?" -------------------------------------------- Yes, many people do get elevated bilirubin because Ribavirin causes hemolytic anemia. See explanation below. "I am not drinking as much water as is suggetsed. Can this cause the bilrubin level to increase?
Avatar m tn I am very sorry that you are in this situation. According to the information about Ribavirin, getting pregnant must be avoided in women taking the drug and if their male partners are taking the drug. Exposure to the drug, regardless of how the exposure takes place, (woman taking the drug, partner taking the drug) can result in severe fetal defects. His doctor should have discussed this with both of you and both you and he should be using precautions to avoid pregnancy.
Avatar m tn 1) HCV Mono-infected and HCV/HIV-1 Co-infected Genotype 1 or 4 SOVALDI + peg-interferon alfa + ribavirin 12 weeks Genotype 2 SOVALDI + ribavirin 12 weeks Genotype 3 SOVALDI + ribavirin 24 weeks * SOVALDI in combination with ribavirin for 24 weeks can be considered for CHC patients with genotype 1 infection who are interferon ineligible. (2.
1116669 tn?1269146866 I would NOT split the tabs. They are coated for a reason. I am sure in this case it is so they absorb at the appropriate time, for the appropriate amount of time, in the appropriate part of the GI tract. Here is a link: Quote: "How should this medicine be used?" . "Ribavirin comes as a tablet, a capsule and an oral solution (liquid) to take by mouth. It is usually taken with food twice a day, in the morning and the evening, for 24 to 48 weeks or longer.
Avatar m tn Hydroxyzine 50 mg every 6 hours (oral antihistamine) Fluocinonide ointment for my body rash Hydrocortisone Valerate cream for my face Clobetesol solution for my scalp The prescription creams and ointments did help, but the rash and itching were not under control until I had a high enough dose of Hydroxyzine oral. You may have to be assertive to get what you need but do have your doctor white some prescriptions for you.
Avatar f tn The American Association for the Study of Liver Diseases (AASLD) recommends a peginterferon alfa product in combination with ribavirin as the preferred therapy for chronic hepatitis C infection.
4748379 tn?1472051653 The Incivek as well as the Ribavirin can cause rashes of various types/appearances. They can be severe. I would strongly suggest that you get on top of this rash right away. These rashes can and do catapult out of control rapidly and they can be severe. I developed a rash at week 10 or so. Benadryl and over the counter Cortizone cream were useless for it. What did work for me was Hydroxyzine 50 mg every 6 hours (oral), Fluocinonide ointment, and Clobetesol soln. They are all prescription.
2030686 tn?1351692148 Conjunctivitis (up to 5%) has been reported with ribavirin capsules/oral solution in combination with peginterferon alfa-2b or interferon alfa-2b. Serous retinal detachment has been reported during postmarketing experience with oral ribavirin in combination with peginterferon alfa-2a, interferon alfa-2b, or peginterferon alfa-2b. " http://www.drugs.com/sfx/ribavirin-side-effects.html Just for the record, I did have some eye problems.
Avatar f tn In the treatment arm that included ribavirin, 25 (100%) achieved an SVR12, compared with 16 (64%) in the arm without ribavirin. In a separate study, investigators used a 12-week course of ledipasvir-sofosbuvir plus ribavirin for 50 treatment experienced patients with genotype 3 HCV, incluing those with cirrhosis. Overall, SVR12 was achieved in 82% of the patients, including 89% in those without cirrhosis and 73% in those with cirrhosis.
1084115 tn?1385232189 I was in the Debio-025 trial, it was my last trial that I did back in 2008. On Debio, I had Riba and Peg and Debio(an oral solution). However, on the Prove 3 Telaprevir trial, which was a Protease Inhibitor trial, I did not get the Ribavirin and I was grouped into Group C, the no Riba group.
Avatar n tn I was prescribed Hydroxyzine 50 mg every 6 hours, Fluocinonide ointment (steroid) twice a day on the rash, Clobetsol solution (steroid) on the scalp. All are prescriptions. The over the counter meds were totally useless. They are not strong enough. Ask your doctor for some prescriptions, like Hydroxyzine orally and some topical steroid ointments or creams. My rash and itching never got under control until I was on both oral Hydroxyzine and the topical prescription steroid ointments.
7829857 tn?1401196259 Have headaches and insomnia but a piece of cake compared to the Interferon/ribavirin. The ribavirin is known to have more problematic side effects. Studies show for most genotypes the SVR rate for this combo isn't too much difference without the Ribavirin. If it's really getting you down talk to your doctor. It may be that the Ribavirin could be dropped? Good luck, hope you get feeling better.
Avatar n tn I am not undergoing any treatment for my Hep C, but I do have it. This past week I have suffered from horrible oral lesions. Went to an oral surgeon, who gave me a special mouthwash & paste to put on the sores. Am I getting this because I have Hep C, or some other virus in my body? I have never had this before .
Avatar m tn I was on triple med Tx with Incivek, Interferon, and Ribavirin. I developed a bad rash and severe itching about week 10. Over the counter meds such as Benadryl and Hydrocorizone cream did absolutely nothing for it.
3156104 tn?1357284795 I also hope you can get through this current treatment with Interferon and Ribavirin. This current treatment, Interferon and Ribavirin, which you are on, has a 69% cure rate in people with Genotype 3. That is a much higher rate of cure than the 56% and 62% cure rate with the newer drugs. Also, even if they were better, which they are not, I am not sure when they will become available in India.
Avatar f tn with my gastro doctor on Jan. 2 to see if I can get started on the all-oral Sovaldi (sofosbuvir) + ribavirin 12-week regimen (I'm genotype 2, treatment-naive). I have BlueCross Federal. If approved, I'll share the news with the forum. Fingers crossed for all of us who have been waiting for this new drug!
1930700 tn?1327068504 ---------------------------------------------------------------- If you have the Q80K polymorphism and treat with Simeprevir (Olysio), Interferon and Ribavirin, the SVR rates are considerably lower than if you did not have the Q80K polymorphism.
789911 tn?1368640383 It is interesting reading and thanks for posting. Effects of Food on Oral Absorption The systemic exposure (AUC) to telaprevir was increased by 237% when telaprevir was administered with a standard fat meal (containing 533 kcal and 21 g (fat) compared to when telaprevir was administered under fasting conditions. In addition, the type of meal significantly affects exposure to telaprevir. Relative to fasting, when telaprevir was administered with a low-fat meal (249 kcal, 3.