Ribavirin hcv

Common Questions and Answers about Ribavirin hcv


476246 tn?1418874514 I know I'm posting terribly much today, but my brain is hyperactive and quite clear today, so I'm trying to use it while it lasts. Dosage Ribavirin 1000mg Considering that I have read that the sx of Riba can be agitating and might make it difficult for you to sleep, would it make sense to take it. Deb_c430 mentions on another thread, if I may quote, that if she takes her riba to late it does cause more agitation and sleeplessness.
1066720 tn?1254997930 Recently he has been diagnosed with HCV Genotype 1. Is there any homopethic medicine for HCV? Also it is also said that Blueberry Leaves stops or lowers HCV virus. How much is this true? If these leaves are beneficial how can we procure the same?
941975 tn?1245425420 My daughter was diagnosed with HCV in March of this year and she was getting ready to start the treatments with interferon and ribavirin. Then when we called to set the first appointment up for treatment they told her that she no longer has HCV all her liver test came back normal, and that she does not have to have the treatments. Is this possible? The letter stated that the HCV RNA by PCR quanatative Not detected, and to repeat the test in 6 months.
Avatar n tn Has anyone been diagonsed with Type II Diabeties that has HCV, that cannot take medication, due to sugar dropping to low, on or off medication? My husband was diagnosed first with type II diabeties than HCV. His sugar level was 800 and even the specialist seemed puzzled, but his sugar levels will drop to 40 at times, this is without medication. Therfore he can not take medication for the diabeties, I wonder if the sugar problems he is having is related to the HCV?
Avatar m tn I did miss some nite doses and I did tell my doc. l also had to cut my hcv meds down due to 1 side effect of a few. Gallbladder may have too come out. Just recently found this GB stuff out. I have another ultrasound scheduled on Mon. 28th. My question is.........what am I to do...to try....my sciatica and arthritis are or rather have crippled me....I am useless and lonely and sick and almost completely insane.
Avatar f tn my hcv pcr rt is negative.but hcv elisa is 1.40 cut off 1.   doctor gave me medicine which name is protak, glif a and rabeadvan.is pain due to hcv antibody?  my age is 26.doctor said that my liver is fatty.how can I recover my liver?
Avatar m tn Ribavirin improves the kinetics of the early response to therapy in patients with an adequate initial response to peginterferon. Induction of interferon-stimulated cytokines correlates with viral kinetics following ribavirin therapy, suggesting that ribavirin promotes interferon signaling. See: http://www.ncbi.nlm.nih.gov/pubmed/20303352 Ribavirin potentiates interferon action by augmenting interferon-stimulated gene induction Hepatology.
10318302 tn?1409260268 Alternate regimen for HCV genotype 4, PEG/RBV nonresponder patients. Daily sofosbuvir (400 mg) and weight-based RBV (1000 mg [<75 kg] to 1200 mg [≥75 kg]) for 24 weeks is recommended for retreatment of HCV genotype 4 infection. Sounds like this is the preferred treatment for your GT 4. I think you will find it easier than your prior treatment since you won't be taking the interferon shots.
Avatar f tn com/hepatitis-c/hepatitis-c-topics/hcv-treatment/3583-easl-ribavirin-dose-reduction-and-epo-both-work-for-managing-anemia-in-patients- Reducing the dose of ribavirin and adding erythropoietin are both good options for managing anemia in hepatitis C patients treated with boceprevir (Victrelis) triple therapy, according to study findings presented at the 47th International Liver Congress (EASL 2012) this week in Barcelona.
Avatar f tn Rapid virologic response occurs in approximately 15% of patients with HCV genotype 1 and 66% of patients with HCV genotypes 2 or 3 treated with peginterferon alfa and ribavirin. 4 It is critically important to identify patients with RVR because these patients have up to a 90% SVR rate if they remain on treatment for 48 weeks for HCV genotype 1 infections (and 24 weeks for HCV genotype 2 and 3 infections.
Avatar f tn Don't have all the numbers but viral load was 23,000,000 and biopsy showed inflammation and bridging fibrosis, (stage 3?). I'm on week 7 out of first 12, pegasys/1000 ribavirin. Doc won't do comprehensive tests to see if working until week 12, then if responding will do 48 weeks. Blood work showed slight anemia this week, he wants me to cut ribavirin to 600. He did say after checking numbers next week we may look into rescue drugs for the anemia.
Avatar f tn 3 Pharmacokinetics The terminal half-life of ribavirin following administration of a single oral dose of ribavirin is about 120 to 170 hours. The total apparent clearance following administration of a single oral dose of ribavirin is about 26 L/h. There is extensive accumulation of ribavirin after multiple dosing (twice daily) such that the Cmax at steady state was four-fold higher than that of a single dose. http://kadmon.com/files/ribasphere-tablets-pi.
Avatar m tn http://en.wikipedia.org/wiki/Ribavirin Pharmacokinetics Ribavirin is absorbed from the GI tract probably by nucleoside transporters. Absorption is about 45%, and this is modestly increased (to about 75%) by a fatty meal. Once in the plasma, ribavirin is transported through the cell membrane also by nucleoside transporters. Ribavirin is widely distributed in all tissues, including the CSF and brain.
310500 tn?1227304634 Only one response on this..... Is this not a concern for others. I hate to see the stuff go to waste as expensive as it is. Can anyone give me an idea. I was given a place in NY, but the link does not seem to work.
Avatar m tn High Ribavirin? I am thinking about trying tx in a clinical trial with high riba. (about two times normal). It seems like a lot of people here who did clear with SOC had more side effects than those who did not clear. I had few side effects but also did not clear. Maybe its the riba I thought jmjm530 cleared using lots of Riba? Anyone else do this or have thoughts?
Avatar f tn I am starting triple treatment soon. I treated in 2008 and I took 1000 mg ribavirin a day and 180 ug of pegasys injection once per week – I reached UND at week 16, but stopped tx because I did not want to treat for 72 wks with low odds and I decided to wait for new PI. Now my (new) doctor is going to treat me with PI and wants to only give me 800 mg of ribavirin a day (I will be taking pegasys and incivek).
135456 tn?1301441224 Does anyone here feel pain and swelling in their liver 1 or 2 hours after taking their ribavirin dose. Can the ribavirin inflame your liver? Also , does anyone know if the "Commitment to Care " program provides ribavirin along with the peg or just the peg alone?
1225178 tn?1318984204 Infection with HCV is much more common than PCT, and most people with HCV do not have PCT. However, at least in some locations, as many as 80 percent of individuals with PCT are infected with HCV. Therefore, HCV needs to be added to the list of factors that can activate PCT alongside alcohol, iron and estrogens. Other hepatitis viruses are seldom implicated in PCT, and it is not known how HCV activates PCT. There are several different viruses that cause hepatitis.
Avatar m tn http://www.medhelp.org/posts/Hepatitis-C/Treatment-for-Hep-C--Grapefruit-Juice/show/542498 “It actually can increase some drug levels because of inhibiting a liver metabolic enyzme. However neither interferon or ribavirin is metabolized by that particular enzyme(p450) so it is OK to drink your grapefruit juice. Stay Healthy!
Avatar n tn Actually...if you review past studies, both HCV, AND Interferon each have a significant impact on erectile function. Several large scale studies from about ten years ago found a rate of ED among HCV positive persons that was close to 35% - 40%, or roughly three to four times higher than the general population at the age ranges studied.
26471 tn?1211940121 Then there is this Abstract Ribavirin Improves Second Phase Kinetics Through Enhanced Interferon Signaling in Genotype 1 HCV Infection Conclusion: Ribavirin improves early viral kinetics, but only in those patients with an initial response to peginterferon.
Avatar m tn org/posts/Hepatitis-C/HCV-Clinical-trial/show/1414377 . So please does anybody knows something about this? I mean corticosteroids plus Pegasus ? May Pegasus provoke my Uveitis which is autoimmune disease I've been suffering for 30 years and taking corticosteroids orally from time to time.
476246 tn?1418874514 Here is something it says on the insert of Copegus. I believe that is what they go after. HCV Genotypes HCV 1 and 4 - Irrespective of baseline viral titer, treatment for 48 weeks with PEGASYS and 1000 mg or 1200 mg of COPEGUS resulted in higher SVR (defined as undetectable HCV RNA at the end of the 24-week treatment-free follow-up period) compared to shorter treatment (24 weeks) and/or 800 mg COPEGUS.
Avatar m tn In order to further characterize the mechanisms of action of ribavirin, we examined the effect of ribavirin treatment on ISG induction in cell culture. In addition, the effect of ribavirin on infectious HCV cell culture systems was studied. Similar to interferon (IFN)-α, ribavirin potently inhibits JFH-1 infection of Huh7.5.1 cells in a dose-dependent manner, which spans the physiological concentration of ribavirin in vivo.
Avatar f tn Ribavirin is an anti-viral drug which is active against a number of DNA and RNA viruses. It is a member of the nucleoside antimetabolite drugs that interfere with duplication of viral genetic material. Though not effective against all viruses, ribavirin has important activities against influenzas, flaviviruses and agents of many viral hemorrhagic fevers. Ribavirin is a pro-drug, meaning that it is a chemical precursor for the actual phamacologically active molecule.
Avatar f tn I have been taking incivek at the same time as the ribavirin and shots on fridays. I, mostly take the pills while I'm eating but always make sure that I have the food or snack with the fat before I swallow the pills. On my week 4, the hcv was undetected, so I will check it again at week 12. I am a 'relapser' after 1 1/2 year before completing the interferon and riba only treatment. My genotype 1.
Avatar n tn How to decide to do interferon/ribavirin? I am having a great deal of ambivalence about beginning this treatment. And a lot of fear. The docs think I should go ahead -- I've probably had Hep C for close to 30 years (I'm 46) from one incident of "we have to try everything once" injecting heroin. I've been diagnosed for 5 years, genotype 2B with a biopsy five years ago grade 1 stage 0. I have quite a bit of fatigue and have struggled (under control at this time) with clinical depression.