Ribavirin contraindications

Common Questions and Answers about Ribavirin contraindications

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Avatar f tn Does anyone know of an actual case of pregnancy and the father is using Ribavirin Ribavirin-interferon-alfa-2a during conception? Need to know the outcome.
217229 tn?1192766004 1 year + 4 months Post TX for Hepatitis C - Cleared SVR / Pegylated Interferon Alpha 2-a combo TX with Ribavirin. 41 year old female. Post Hysterectomy January 22, 2008 one ovary remaining and functioning.
Avatar f tn 1 Significant teratogenic and/or embryocidal effects have been demonstrated in all animal species exposed to Ribavirin. In addition, Ribavirin has a multiple dose half-life of 12 days, and it may persist in non-plasma compartments for as long as 6 months. Therefore, Ribavirin, including Ribavirin tablets, is contraindicated in women who are pregnant and in the male partners of women who are pregnant.
Avatar f tn All I can tell you is, my hepatologist told me not to take it while I was treating. I know it weakens your immune system, can raise your BP (and so can Sofosbuvir), etc. I would consult with your physician and the prescribing pharmacist for Sofosbuvir. Gilead's support will not be of much help. They will read you a list of known contraindications but will not advise on specific medications as you're inquiring about.
Avatar f tn Anemia The primary toxicity of Ribavirin is hemolytic anemia, which was observed in approximately 13% of all Ribavirin/peginterferon alfa-2a- treated subjects in clinical trials. Anemia associated with Ribavirin occurs within 1 to 2 weeks of initiation of therapy. Because the initial drop in hemoglobin may be significant, it is advised that hemoglobin or hematocrit be obtained pretreatment and at week 2 and week 4 of therapy or more frequently if clinically indicated.
Avatar m tn Dear Dr. I am curently enrolled in a study that includes ribavirin. I heard of other people that have used wheat grass juice and/or sublingual B12 to help improve CBC counts. Is this approach reasonable, or do you think that there are contraindications to doing this? Thank you.
Avatar f tn Significant teratogenic and/or embryocidal effects have been demonstrated in all animal species exposed to Ribavirin. In addition, Ribavirin has a multiple dose half-life of 12 days, and it may persist in non-plasma compartments for as long as 6 months. Therefore, Ribavirin, including Ribavirin tablets, is contraindicated in women who are pregnant and in the male partners of women who are pregnant.
Avatar n tn I have a patient who has Hepatitis C and also multiple sclerosis and his physician wants him to be started on treatment with long acting interferon alfa 2b and Ribavirin based on patient's weight. Are there any contraindications to treating this patient? As a nurse what side-effects should I tell the patient to watch for other that the usual ones that are well documented? I would appreciate any information you could give me on this issue. Many thanks.
Avatar f tn Doctor gave her PEG-Inteferon 80 (according to her weight). 5. They could not give her Ribavirin because her hemoglobin is 9 most of the time. 6. Her response to treatment is very slow. Reading about Molixan, I thought it would be the medicine of choice. The question is: 1. Molixan is not available but Glutoxim is available. Are they the same medicine? 2. Can we give Glutoxim at the same time she is taking PEG-Interferon? Would there be any contraindications?
Avatar m tn I cleared in the trial on Viekira Pak. There were no contraindications (except alcohol) or requirements to eat anything special. Some people find it helpful to eat if you are taking ribavirin and it is bothering your stomach. I had absolutely no problems.
Avatar f tn RISK OF SERIOUS DISORDERS AND RIBAVIRIN ASSOCIATED EFFECTS "Significant teratogenic and embryocidal effects have been demonstrated in all animal species exposed to ribavirin. Therefore, COPEGUS is contraindicated in women who are pregnant and in the male partners of women who are pregnant.
4333925 tn?1359106042 At least two reliable forms of effective contraception must be utilized during treatment and during the 6 month post treatment follow-up period [see Contraindications (4), Warnings and Precautions (5.1), and Use in Specific Populations (8.1)]. Ribavirin therapy should not be started unless a report of a negative pregnancy test has been obtained immediately prior to planned initiation of therapy.
Avatar n tn Significant teratogenic and/or embryocidal effects have been demonstrated in all animal species exposed to ribavirin. In addition, ribavirin has a multiple dose half-life of 12 days, and it may persist in non-plasma compartments for as long as 6 months. Therefore, ribavirin, including Copegus, is contraindicated in women who are pregnant and in the male partners of women who are pregnant.
Avatar n tn Because INCIVEK must be used in combination with peginterferon alfa and ribavirin, the contraindications and warnings applicable to those drugs are applicable to combination therapy. Female patients of childbearing potential and their male partners as well as male patients and their female partners must use 2 effective contraceptive methods during treatment and for 6 months after all treatment has ended.
Avatar f tn Therefore, studies to define shorter regimens, as well as strategies to substitute a less toxic STAT-C agent for another agent such as ribavirin, will likely be conducted using noninferiority study designs. This same period will also likely see the development of multidrug (at least 3 drugs) combination regimens to attempt to produce SVR without dependence on interferon with or without ribavirin backbones.
Avatar m tn Current HCV therapy includes up to 12 months of weekly interferon injections which can be associated with significant side effects. In addition, not all patients can take interferon due to intolerance or contraindications. We look forward to the results of additional studies with these potent compounds." The collaborating companies announced that Roche will initiate a Phase 2 trial program in the first quarter of 2010.
1253246 tn?1332076910 Absolute Contraindications to Pegylated Interferon Alpha and/or Ribavirin **** They shouldn't need to test for any of these things, since they would stand out on your medical records. If any of these things are an issue with you, you need to make sure you and your doc know what you're doing and have some back up plans in mind.
Avatar m tn thanks very much. are there any contraindications for this combination?
Avatar n tn I'm having a terrible time finding information on post-treatment SVR female patients who have become pregnant or are trying to become pregnant. I am aware of all the contraindications during treatment and six months post-treatment. But I haven't been able to find anything past that time frame. Does anyone have any links or resources they can point me to? It'd be greatly appreciated. Here's to SVR for everyone.
Avatar m tn I took the Sovaldi @ 8:00 am along with 3 Ribavirin, with food, usually a couple of large tablesppons od plain greeklike yogurt, some fresh fruit of some sort, and almonds. At night @ 8:00pm I took the other 3 Riba, also with a light, liver friendly, meal.
Avatar m tn A Multicenter Compassionate Use Protocol of Daclatasvir (BMS-790052) in Combination With Sofosbuvir With or Without Ribavirin for the Treatment of Subjects With Chronic Hepatitis C http://clinicaltrials.gov/ct2/show/NCT02097966 Excerpts Expanded access is currently available for this treatment.
446474 tn?1446351282 Patients should be informed that serious acute hypersensitivity reactions have been observed during combination therapy with VICTRELIS, peginterferon alfa, and ribavirin therapy[see Contraindications (4) and Warnings and Precautions (5.4)]. If symptoms of acute hypersensitivity reactions (e.g., itching; hives; swelling of the face, eyes, lips, tongue, or throat; trouble breathing or swallowing) occur, patients should seek medical advice promptly.
Avatar n tn Because Incivek must be used in combination with peginterferon alfa and ribavirin, the contraindications and warnings applicable to those drugs are applicable to combination therapy. Female patients of childbearing potential and their male partners as well as male patients and their female partners must use 2 effective contraceptive methods during treatment and for 6 months after all treatment has ended.
Avatar f tn Because INCIVEK must be used in combination with peginterferon alfa and ribavirin, the contraindications and warnings applicable to those drugs are applicable to combination therapy. Female patients of childbearing potential and their male partners as well as male patients and their female partners must use 2 effective contraceptive methods during treatment and for 6 months after all treatment has ended.
Avatar f tn Among the regimens that have been approved by the FDA for patients with HCV genotype 1 infection who have not had a sustained virologic response to prior interferon-based therapy — historically, the population hardest to cure — are 12 weeks of sofosbuvir with peginterferon and ribavirin or 24 to 48 weeks of simeprevir with peginterferon and ribavirin.
Avatar m tn The standard of care is pegylated interferon with ribavirin. There are some protease and polymerase meds in trial and hopefully will be available in 4 or 5 years. They will be used with iterferon and ribavirin. 3- What diet can help srengthen her liver? The only dietary things would be to stay away from alcohol. There are no foods that strengthen the liver. 4- Is there any chance that I get it? The chance is very small.
Avatar f tn I am genotype 3 on treatment for 24 weeks with sofosbuvir and ribavirin. I am currently on day 49 and so far have not been able to return to work. The side effects seem to wax and wane, but so far am still struggling. My doctor says after six to eight weeks it should get better, but so far not the case for me and I cannot imagine doing this another for months.
Avatar f tn Patients with anti-HCV, HCV RNA, elevated serum aminotransferase levels, and evidence of chronic hepatitis on liver biopsy, and with no contraindications, should be offered therapy with the combination of peginterferon and ribavirin. The National Institutes of Health Consensus Development Conference Panel recommended that therapy for hepatitis C be limited to those patients who have histological evidence of progressive disease.
Avatar m tn Pegylated Interferon/Ribavirin has been suggested by the Gastroenterologist. The Gastro. Doc. says he finds no contraindications for being on Trileptal and taking Peg. Interferon/Ribavirin but I know I found a medical site on the internet that said you couldn't do both at the same time. Anyone know?? Also, (sorry for the length here), his Pancreas is slightly enlarged on the lower end so waiting for CT results on Sept.12 about this from the Gastro Doc. Is this common with Hep. C folks.
Avatar f tn Interferon alfa-2b/ribavirin Sudafed 12 Hour Pressure+Pain (naproxen/pseudoephedrine) Sudafed PE Cold & Cough (acetaminophen/dextromethorphan/guaifenesin/phenylephrine) http://www.drugs.com/interactions-check.php?drug_list=1356-0,1691-14288,56-13172 Add / Remove drugs Interactions between your selected drugs No results found - exist. ALWAYS consult with your doctor or pharmacist.