Ribavirin cancer

Common Questions and Answers about Ribavirin cancer


Avatar n tn Ok just blame it on being distracted! I usally take my ribavirin in the morning (at work) and at dinner (at home) I didn't realize it but I was one pill short (I take 6 a day) this morning at work. Make it up at dinner or not or not is the quesiton. Dare I ask the next question? Has anyone ever felt better while on treatment then before treatment. I know from what I read here a crazy quesiton. But I would swear that I felt better on Saturday (finishing week 7 of tx) then I have in a long time.
476246 tn?1418874514 I know I'm posting terribly much today, but my brain is hyperactive and quite clear today, so I'm trying to use it while it lasts. Dosage Ribavirin 1000mg Considering that I have read that the sx of Riba can be agitating and might make it difficult for you to sleep, would it make sense to take it. Deb_c430 mentions on another thread, if I may quote, that if she takes her riba to late it does cause more agitation and sleeplessness.
Avatar f tn I am starting triple treatment soon. I treated in 2008 and I took 1000 mg ribavirin a day and 180 ug of pegasys injection once per week – I reached UND at week 16, but stopped tx because I did not want to treat for 72 wks with low odds and I decided to wait for new PI. Now my (new) doctor is going to treat me with PI and wants to only give me 800 mg of ribavirin a day (I will be taking pegasys and incivek).
Avatar m tn http://en.wikipedia.org/wiki/Ribavirin Pharmacokinetics Ribavirin is absorbed from the GI tract probably by nucleoside transporters. Absorption is about 45%, and this is modestly increased (to about 75%) by a fatty meal. Once in the plasma, ribavirin is transported through the cell membrane also by nucleoside transporters. Ribavirin is widely distributed in all tissues, including the CSF and brain.
Avatar f tn This was shown in a retrospective analysis of a large, randomized, placebo-controlled trial in which patients who achieved RVR had an SVR rate of approximately 90% regardless of whether they received peginterferon alfa and ribavirin, standard interferon and ribavirin, or peginterferon alfa monotherapy. In addition, the likelihood of SVR patients with genotype 1 infection who achieve an RVR does not appear to be affected by shortening the duration or reducing the dose of ribavirin.
Avatar m tn I am 9 months post transplant for liver cancer (HCC) and will be starting Sovaldi, Olysio and ribavirin on August 28th as my 3 attempts at curing my hepatitis C. Right now I am finishing 9 months of treating my tuberculosis with a drug that can not be taken with Sovaldi. I was one of the first 61 cirrhotics ever to treat with Sovaldi 2 years ago when I was in the trial that got FDA approval for the treatment of folks with liver cancer awaiting liver transplant with Sovaldi.
Avatar f tn Ribavirin is an anti-viral drug which is active against a number of DNA and RNA viruses. It is a member of the nucleoside antimetabolite drugs that interfere with duplication of viral genetic material. Though not effective against all viruses, ribavirin has important activities against influenzas, flaviviruses and agents of many viral hemorrhagic fevers. Ribavirin is a pro-drug, meaning that it is a chemical precursor for the actual phamacologically active molecule.
Avatar f tn Quite sure the same thing happens to people who undergo cancer therapy or any other long term drug therapy. http://www.medhelp.org/posts/Hepatitis-C/Long-term-side-effects-of-interferon/show/866107 http://www.medhelp.org/health_pages/Hepatitis/Members-Comment-on-Side-Effects-of-the-Treatment-Drugs-During--After-Treatment-/show/530?
446474 tn?1446351282 2 200 mg of GS-7977 in morning 3 200 mg of Ribavirin in morning 3 200 mg of Ribavirin at night (12 hours later) But I am now on treatment and will continue for 24 weeks or transplant, which ever comes first. I stopped my TB treatment today. I will deal with TB after transplant. I just had a cancer screen MRI/AFP and I am waiting for the results... I can't believe that within 4 weeks I will have no viral load for the first time in 42 years!!!
135456 tn?1301441224 Ribavirin is known to cause anemia (low red blood cells), which can make heart disease worse. Also, ribavirin can harm your DNA and possibly cause cancer (see medication guide for more information and warnings). Who should not take PEGASYS and COPEGUS?
Avatar f tn I read on my drug handout that Ribavirin is a potential cancer causing agent.......this was written under warning with the Peginterferon alfa-2a that I received. That's really encouraging.......I don't think so. Boy, learning new stuff all the time. Also, does anyone know if it is NOT all right to have the peg-int. shot on the same day as a booster Hep B vacine? I am scheduled to have #2 for Hep B vacine in couple weeks, and noticed it's same day as I take peg-int. dose.
446474 tn?1446351282 If I can beat this cancer, I can beat hep C with new treatments. On to cancer treatment #5 with CyberKnife radiation treatment for untreatable tumors. I will be the first patient at my transplant center to have this treatment for liver cancer. Depending on how my treatment goes the transplant center is thinking of adding this treatment as an option for others in the future with HCC. I am happy to be a pioneer if I can help others with their HCC. Life goes on with or with HCC.
Avatar m tn The good news for me was that during the treatment my liver disease improved enough so that I could have the 6 different cancer treatments I needed to get my cancer under control and within transplant criteria so I was eligible to get a transplant. So in way even though I failed the treatment it helped to save my life. As your doctors mentioned HCC recurrence in common once cirrhosis has developed to the point of the occurrence of HCC.
446474 tn?1446351282 2 200 mg of GS-7977 in morning 3 200 mg of Ribavirin in morning 3 200 mg of Ribavirin at night (12 hours later) I just had a cancer screen MRI/AFP and I am waiting for the results... But I am now on treatment and will continue for 24 weeks or transplant, which ever comes first. I stopped my TB Rifampin treatment today. Can't take Rifampin while on trial. I will deal with my TB after transplant. I can't believe that within 4 weeks I will have no viral load for the first time in 42 years!!!
446474 tn?1446351282 I found out today I AM UNDETECTABLE after 2 weeks of treatment with GS-7977 and Ribavirin. Not bad for a previous null-responder to peg-INF and Ribavirin where after 12 weeks of treatment my viral load never went below 360,000. "An Open-Label Study to Explore the Clinical Efficacy of GS 7977 With Ribavirin Administered Pre-Transplant in Preventing Hepatitis C Virus (HCV) Recurrence Post-Transplant" ClinicalTrials.
Avatar f tn I finished a year-long treatment of Pagasys and Ribavirin in 06/2008. It was successful! 18 months later however, I'm feeling little change from when I was taking the drugs. I'm having problems in many areas. I have chronic fatigue, "brain fog", short-term memory loss, rare but severe memory loss (like a blackout, during which I've had conversations, driven, walked, eaten), lack of focus, difficulty with spacial issues, tremors, acute joint pain, clumsiness and more.
Avatar m tn That is why Slovaldi is the only FDA approved drug along with ribavirin for those with liver cancer. This doesn't mean that sovaldi and oylsio wouldn't also work but there is no data. "8.
Avatar m tn Interferon, Interferon + Ribavirin, and Interferon+Ribavirin+Tepavier. I also have compensated cirrhosis. I've had HEPC for over 50 years. Currently I'm on week 4 of Havoni + Ribavirin (1200 mg a day + 1 Harvoni). I read that the recommended duration for we hard-to-treat previous non-responders is 24 weeks, but my clinician is insisting 12 weeks will be good enough and there is no difference in the outcomes for 12 weeks vs 24 weeks. Is this correct data?
Avatar f tn Anemia The primary toxicity of Ribavirin is hemolytic anemia, which was observed in approximately 13% of all Ribavirin/peginterferon alfa-2a- treated subjects in clinical trials. Anemia associated with Ribavirin occurs within 1 to 2 weeks of initiation of therapy. Because the initial drop in hemoglobin may be significant, it is advised that hemoglobin or hematocrit be obtained pretreatment and at week 2 and week 4 of therapy or more frequently if clinically indicated.
Avatar m tn 16 Ribavirin The synthetic purine nucleoside Ribavirin rapidly enters eukaryotic cells and after intracellular phosphorylation exhibits virustatic activity against a broad spectrum of DNA and RNA viruses.25 Several studies have been conducted to evaluate ribavirin monotherapy in daily doses of 600-1,200 mg in the treatment of chronic hepatitis C.26-28 While all trials consistently showed a decrease in aminotransferase levels, no virologic end-of-treatment responses were observed.
173930 tn?1196341998 Prediction of sustained virological response in chronic hepatitis C patients treated with peginterferon alfa-2a (40KD) and ribavirin. Foster GR, Fried MW, Hadziyannis SJ, Messinger D, Freivogel K, Weiland O. The Royal London Hospital. London. UK. Objective. Patient- and virus-related factors influence the response of patients with chronic hepatitis C to interferon-based therapy.
Avatar f tn Hi Ginger. You should talk to your oncologist first. Just to be safe. "* That ESAs shortened overall survival and/or increased the risk of tumor progression or recurrence in clinical studies in patients with breast, non-small cell lung, head and neck, lymphoid, and cervical cancer." Not sure if being cured of breast cancer, procrit still has negative affect on cancer growth or reoccurance. I would definitely check with your oncologist BEFORE talking Procrit.
Avatar n tn HI, some will know where to go to get this answer, I seen it once and wrote down out of curiosity, AND it says alpha fetaprotein if elevated is cancer. Now I only read that on test results somewhere BUT MDS are the answer for that one. so ask YOUR MD is the one to ask!!! I wish you blessings and hope you find out what you want to know. Dont rush to answers with negativity , I dont think thats good, think positive and definatly talk to MD.
Avatar f tn Doc says that Hep c can lead to liver cancer. She scared me. is a gasterologist the same as a hepitologist? I was diagnosed w/hep c in 1995. What tx is available? thank u for any help anyone can provide me with.
4705307 tn?1447973922 My sister died of liver cancer after she successfully treated and achieved SVR. The cancer was caused by her very cirrhotic liver after years of living with HCV. That is the only connection. I know treatment is rough on most folks especially if one's health is already compromised but in all my readings and listening to other's stories I have never heard that treatment can cause cancer. It is a very sad coincidence in my opinion.
766573 tn?1365170066 [1] The retrospective sub-analysis of the Phase 3 REALIZE trial evaluated the impact of ribavirin dose reduction on SVR rates of previously treated genotype-1 chronic HCV patients who received treatment with telaprevir in combination with peginterferon alfa and ribavirin (T12PR48) or peginterferon alfa and ribavirin alone (PR).[1] Results were categorized according to patients' previous response to treatment.
Avatar f tn I was recently diagnosed with breast cancer. My breast cancer treatment will be radiation treatment for a month or so, and I will have to take hormone therapy (for example, tamoxifin) for 5 years. I have hep c and was planning to treat with interferon and ribavirin, and with the new PI telaprevir or boceprevir - as soon as either one is available. Does anyone know if there will be any added issues that I should be aware of when getting the hep c treatment while on hormone therapy? Thanks.
Avatar m tn I completed chemotherapy in august 2010 for lymphoma and started interferon/ribavirin treatment for hepc in november 2010. I am currently through week 44 of 48. I had regular PET scans post chemo with no suspicious activity. In early 2011 I developed many ailments that I (and my gastro, oncologist and PCP) attributed to the interferon/ribavirin treatments.
Avatar m tn Hopefully you can get some suggestions from the Cancer forum, Cirrhosis of the Liver Forum, Transplant forum, Ask a Doctor forum and Liver Disorders forum as mzkity suggested. I would ask in every forum that pertains to your mothers current condition. Even though she has Hepatitis C - Her current condition of Cancer is the main focus and any treatment that might be available for treating her HCC.
1125489 tn?1309309471 I am lucky in not having a detectable amount of hep C in my blood after six years, but I have developed, in the past two or three years, atrial fibrillation and hypertrophic cardiomyopathy, and I'm wondering if this could have been brought on by the pegylated Interferon / Ribavirin therapy because I was under a lot of stress during treatment and felt some of the same symptoms that I have now. Thank you.