She may finally have eaten something that will not pass through her digestive system, or is causing an obstruction, or may be causing pancreatitis, or it could be something unrelated, such as impacted anal glands.
Pancreatitis is
a severe, debilitating disease and requires
in-hospital care, whereas anal gland impaction can be relieved by an anal gland expression.
Please take her to the vet just in case.