Parkinson's Plus is a term used to refer to a number of conditions that initially resemble Parkinson's disease, but are less likely to respond, if at all, to Parkinson's medications. Prognosis is poor, with a rapid decline and earlier death than PD. The following syndromes are included under the umbrella term of Parkinson's Plus: Multiple System Atrophy (MSA, Shy-Drager), Lewy body dementia, progressive supranuclear palsy, corticobasal degeneration, and PD with ALS.