Other than restless leg syndrome other possibilities that may need to be considered are vascular issues, peripheral neuropathy, musculopathies, hormonal/ endocrine issues, micronutrient deficiencies, infections, stress/
depression etc. Without an evaluation it would be difficult to say what effect would a particular drug have on it. I would suggest consulting an internist, preferable at a university/ teaching hospital for an evaluation and appropriate management.
Hope this helps.
Take care!