letrozole versus tamoxifen

Side effects seen more often with tamoxifen versus Femara were hot flashes and vaginal bleeding. Joint pain was experienced more often with Femara versus tamoxifen. ref: http://www.femara.com/home.jsp?m=2 Additional side effects for both Femara and tamoxifen are heart attack, thromboembolic events, endometrial cancer and second malignancies. bOTH THE DRUGS CAN CAUSE GAIN IN WEIGHT.

Side effects that are comparable between Femara and tamoxifen include night sweats, weight gain, nausea and tiredness. Side effects seen more often with tamoxifen versus Femara were hot flashes and vaginal bleeding. The benefits of FEMARA in clinical trials are based on 24 months of treatment. Further follow-up is needed to determine long-term results.(http://www.femara.com/content/femara-what-is.jsp) Take care and regards.

This was tried years ago, since tamoxifen structurally is similar to clomid. Tamoxifen works, however clomid works better.

The Doctor recently traded out her Tamoxifen for Letrozole. As far as I know, Tamoxifen is used to prevent the large majority of the hormone being fed on by the cell, whereas Letrozole is supposed to stop the body producing it completely. My mother is 49 at the moment, 50 on September 10th. Her doctor also said that Letrozole can only slow the process down. I have been researching like mad for the last two days, looking up all kinds of treatments.

(beyond the initial 5 years) is with letrozole (Femara) after 5 years of tamoxifen. Letrozole and anastrozole (Arimidex) are both aromatase inhibitors and are very similar to one another. In most of the adjuvant studies using these drugs, 5 years of treatment has been given. An ongoing study will compare 5 to 10 years of aromatase inhibitors but there are no results available yet on that study.

I know everyone is different and all that but thought maybe someone can share their experiences or other knowledge about Aromasin? I was on Tamoxifen, then switched to Arimidex which was a nightmare. Then Femara which was a little less horrible but too horrible to continue. The I went back on tamoxifen and today I saw my oncologist and he wants me to try Aromasin. He says the reason is mostly because of my taking prozac, and the problems this can cause with Tamoxifen.

I took Tamoxifen for 5 years and had no side effects At all. I have friends who have also taking Tamoxifen with no side effects. Best To You - 13 year breast cancer survivor.

Systemic therapy in the form of tamoxifen can also be given in hormone receptor positive disease. There is currently no consensus regarding the optimal treatment of DCIS. Radiotherapy after surgery in DCIS is done in order to decrease the risk local recurrence. Numerous studies already support this approach. Comparing radiotherapy versus no radiotherapy, there is an advantage in decreasing local recurrence, with a risk reduction of about 40-50%. Hope this helps.

I am 63 and just diagnosed with Stage 1, ER/PR Positive, node negative invasive ductal carcinoma. My oncologist is in the process of deciding whether to prescribe Letrozole/Femara or Anastrozole/Arimidex. What considerations factor into which of these two drugs to use? Has anyone had experience with either of them? How serious are the side effects?

Has anyone ever used Letrozole? Was it beneficial? Did you get a BFP? Any side effects?

You welcome! Just a suggestion about hormonal therapy to lower estrogen levels. If you are post menopausal,and your bone density test doesn't show you have osteoporosis,you could ask your doctor to prescribe a much less expensive drug,like Femara's generic version "Letrozole" or Arimidex generic version "Anastrazol" If you are pre-menopausal, then Tamoxifen would be also good and I believe it's the least expensive one. I hope this helps...

I have quit my Tamoxifen after two months due to my terrible sleeping (hot flashes) or not sleeping would be the term. I went off HRT when diagnosed last spring -- stage 1, a 1.1 cm tumor with a .25 tumor off the side of that. My nodes were clear. I had resumed hot flashes after quitting HRT but they were much worse at night with the Tamoxifen. From my reading I understand it is much more controversial than presented by my oncologists.

Gave me symptoms. I am now on letrozole. Also experiencing symptoms. Will letrozole keep this cancer away. Is there a smaller does than 2.5 of letrozole that I can take.

Hi! Doctors will prescribe either clomid or letrozole to assist with ovulation. There's two main differences: it doesn't have anti-estrogenic side effects like clomid; and although studies have proven letrozole is an effective fertility drug it hasn't been approved by the FDA yet for fertility use, thus isn't covered by insurance (beware it's very expensive). Letrozole was developed to treat estrogen-sensitive breast cancers.

There have been studies looking at anti estrogen and anti aromatase drugs for women with recurrence ovarian cancer. The drugs that have been used include tamoxifen, arimidex, letrozole. The response rate has varied from 0 to 50 %.. there may be correlation with the hormone receptor status of your tumor but this has not been well studied. the side effects of these drugs are few - hot flashes, vaginal dryness, risk of blood clots, and more rarely prescription eye changes.

Hello, my husband and I have been trying to conceive since we've gotten married 8 yrs ago. I was diagnosed with pcos (polycystic ovarian syndrome) in 2006. I'm not overweight, and my cycles come every month but not consistently. Well, this entire month of Nov., I have not gotten my period. I thought I might finally be pregnant so I went to my dr. and the test was negative. How can this be?? I get my period every month, finally miss a cycle, and it's negative?

I have been on letrozole for 5 months now and nothing.I had a miscarriage in march and have been taking this since march.The only side effects I have had are hot flashes in the beginning but I do get stabbing headaches occasionally.Has anyone else had to go from letrozole to something else that helped get them pregnant.

This leasion corresponds to the mmagographic abnormality. The differential includes a papilloma versus possibly a small carninoms such as a papillary or medullary carcinoma. Surgical excision is recommended. I am seeing surgeon next week. 1. What does this mean? 2. What to the mean when they say differential includes... 3. How serious are papillary or medullary carcinoma? 4. If biopsy is positive, what is normal treatment regimen? Thank you.

Has anyone ever used Letrozole? Was it beneficial? Did you get a BFP? Any side effects?

Anyone get pregnant using femara/letrozole after being given unexplained infertility diagnosis? How many months did you take it before you got your positive? Me: 28 Hubby: 30 Sperms analysis perfect, laparoscopy perfect, all tests for ovulation and ultrasounds looked perfect. Trying since 2012 no pregnancy yet This is my 2nd cycle on femara, next ovulation expected on 1/14. If 3rd cycle not successful, will do iui with femara anyone else done this and got pregnant? ?

I used to have 9 to 16 days of bleeding before letrozole! After being on letrozole, how many days are you bleeding? This is my second time with Letrozole and I had 9 days of bleeding the first time. By Day 5 I'm ready to quit letrozole because it makes my bones a bit achy, my breasts are super tender and less firm, and overall I feel like I constantly have a buzz that you get with one glass of wine.

I have just been diagnosed with breast cancer and have been offered a trial on Letrozole before and after surgery along with radiotherapy. I would appreciate knowing any side effects when taken along with Lithium and mood swings suffered if any.

Letrozole versus tamoxifen

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