Letrozole vs tamoxifen

Common Questions and Answers about Letrozole vs tamoxifen

femara

284773 tn?1207757759 This was tried years ago, since tamoxifen structurally is similar to clomid. Tamoxifen works, however clomid works better.
Avatar n tn I am slowly seeing a few pounds come off whereas on Tamoxifen nothing came off no matter how hard I tried. Is it possible that I am losing the tamoxifen weight and will not gain on Femara.
Avatar n tn I don't know about Femara but I have gained weight on Tamoxifen. I get to stop taking it next month and I can't wait to see if I lose some of this weight.
Avatar m tn The Doctor recently traded out her Tamoxifen for Letrozole. As far as I know, Tamoxifen is used to prevent the large majority of the hormone being fed on by the cell, whereas Letrozole is supposed to stop the body producing it completely. My mother is 49 at the moment, 50 on September 10th. Her doctor also said that Letrozole can only slow the process down. I have been researching like mad for the last two days, looking up all kinds of treatments.
Avatar n tn Hi. How old are you? Are you post-menopausal? Exemestane (Aromasin) and similar drugs called aromatase inhibitors, will only work with women who have already undergone menopause. If you're in the reproductive age group, Tamoxifen is still your primary option for hormonal treatment.
Avatar f tn Perimenopausal breast cancer survivor on tamoxifen. After 4 months, diagnosed with AUB due to simple hyperplasia and polyps. Given a choice of hystrectomy or Ablation. Can't find any literature regarding ablation followup care since tamoxifen would be continued for 2-3 more years. What is the risk of endometrial carcinoma or other gyn issues after ablation since tamoxifen would still be providing an estrongenic effect?
1030058 tn?1252253572 (beyond the initial 5 years) is with letrozole (Femara) after 5 years of tamoxifen. Letrozole and anastrozole (Arimidex) are both aromatase inhibitors and are very similar to one another. In most of the adjuvant studies using these drugs, 5 years of treatment has been given. An ongoing study will compare 5 to 10 years of aromatase inhibitors but there are no results available yet on that study.
Avatar n tn Has anyone done letrozole vs clomid? side affects? BFPs? also - i will be in NY when Af starts - and will hopefully make it back somewhere between CD2-5 or i will have to have CD3 labs and US done up there and rx called in there as well. so nervous and hesitant to spend so much $ - esp when we have a blessing with our 2.5 yr old. thoughts?
Avatar f tn He tried me on one more round of clomid 150mg to no avail. I had an HSG done and all tubes were clear. I was then put on letrozole (femara) days 3-7. Went in on day 14 for an u/s and had a follicle measuring 17.5mm. Did OPK for a few days and got my +. Went in the following day and had IUI. I am now 12.5 weeks pg with TWINS! It can and it does work!!!
Avatar f tn It does act as an anti-estrogen but also acts like estrogen in that it prevents the bone loss that other drugs like Tamoxifen may cause. It actually has the same side effects as Tamoxifen but not every person will experience all of these side effects or to the same degree. I'm not sure what you mean by "it made me ill" ... you may have the same side effects with the other drug but it's worth a try. Regards ....
Avatar f tn Hi, I can't seem to find stats anywhere on the Web for Stage I Breast Cancer, if you've had BCS but no radiation. Even stats for Tamoxifen,eg, all seem to assume you've had radiation. I had a lumpectomy; lymph nodes are clear, the tumour is only 1.1 cm, invasive tubular, as well as DCIS and one focal point of LCIS.
Avatar n tn Hi. I'm on tamoxifen so I can't take any meds which inhibit cyp2D6 enzymes. I've been on almost ALL SSRI ( Effexor, lexapro, celexa, nortriptyline, fetzima, & viibryd) & my depression worsens with them (suicidal thoughts, etc). The only one that has helped is remeron but every time I've had to return to remeron I gain weight. I'm usually 110-112 and eat very well & workout almost everyday.
Avatar n tn Herceptin and Tamoxifen are different drugs with entirely different actions. One does not replace the other in treatment. Tamoxifen blocks Estrogen and Herceptin deals with the over production of a protein. They are often given together. As the previous poster stated; if your tumor was Her2 positive you should definitely follow the Herceptin recommendation. Regards ...
Avatar f tn I was recently diagnosed with DCIS, ER/PR negative and, because of extremely dense breasts, chose to have a bilateral mastectomy. I'm glad I did, because a 5mm invasive tumor was found. The tumor was Grade 1, ER/PR postive, Her-2 negative. My oncologist recommended doing nothing or, if I wanted to have some treatment, receommended tamoxifen. I've heard that Tamoxifen doesn't kill microscopic cancer cells elsewhere in the body but only inhibits their growth...
Avatar f tn Just to add to what Lauren said regarding tamoxifen vs. other AI's, they do work differently in the body. Tamoxifen works by blocking the body's use of estrogen, whereas AI's reduce the amount of estrogen present in the body. In studies of breast cancer patients, AI's have proven to work better than tamoxifen in preventing recurrence, and there are far fewer serious side effects with AI's than with tamoxifen, too. Tamoxifen can cause blood clots, and stroke..
Avatar n tn Hello, I'm writing on behalf of my wife, she is 42 years old, premenopausal, and being treated (radiation therapy to come) for invasive ductal carcinoma, without any evidence of spread to nearby lymph nodes or distant sites, 1/0,8 mm tumor, low/moderate grade tumor, er+, pgr+, no family history of breast/ovarian cancer. Although our oncologist generally treats young women more aggressively, my wife's tumor is so small he has recommended just radiotherapy.
Avatar m tn I just saw a film Cut Poison Burn that pretty much said what the lady's dr in Puerto Rico advised: not only does the use of tamoxifen double the patient's chances of uterine cancer but taking it more than five years also increases the chances of breast cancer. Why would you advise a lady who does not have cancer to take a drug that causes cancer?
Avatar f tn m a big fan ( i never took clomid, since i have endo, they wanted me straight to femara(letrozole)) it doens't thin your lining like clomid and doesn't strip away cervical mucus like clomid can for some people.. we did femara two cycle, then femara and follistim the last one (all with IUI's - we have a TON of issues!!) and we did get preg! : ) miscarried at 9 weeks, but it did work which is huge!!! GOOD LUCK!!! my prayers are with you! let us know if yo uhave any questions!
256553 tn?1258883918 Has anyone ever used Letrozole? Was it beneficial? Did you get a BFP? Any side effects?
Avatar n tn You welcome! Just a suggestion about hormonal therapy to lower estrogen levels. If you are post menopausal,and your bone density test doesn't show you have osteoporosis,you could ask your doctor to prescribe a much less expensive drug,like Femara's generic version "Letrozole" or Arimidex generic version "Anastrazol" If you are pre-menopausal, then Tamoxifen would be also good and I believe it's the least expensive one. I hope this helps...
Avatar f tn The test also said that people with scores of 31 or higher had a 40% chance of recurrence with Tamoxifen alone, and 12% with Tamoxifen and CMF/MF. My oncologist said that the chemo drugs used in this study are old, and the outcome could even be 30% better with the new drug combos. Are there studies like this using my score and the new chemo drugs?
Avatar m tn Gave me symptoms. I am now on letrozole. Also experiencing symptoms. Will letrozole keep this cancer away. Is there a smaller does than 2.5 of letrozole that I can take.
1190279 tn?1324936257 Hi! Doctors will prescribe either clomid or letrozole to assist with ovulation. There's two main differences: it doesn't have anti-estrogenic side effects like clomid; and although studies have proven letrozole is an effective fertility drug it hasn't been approved by the FDA yet for fertility use, thus isn't covered by insurance (beware it's very expensive). Letrozole was developed to treat estrogen-sensitive breast cancers.