Researchers treated six people with HBV-related cirrhosis with lamivudine doses raised from the normal dose of 100 mg daily to 200 or 300 mg daily, based on their viral load. Previously, nearly all of these patients had developed lamivudine resistance at the lower, 100 mg-dose, and had failed to improve even after the antiviral adefovir (Hepsera) (10 mg daily) was added to their ongoing lamivudine treatment.
stop lamivudine immediately or switch to tenofovir, it is decades now lamivudine is not used because it can lead to cytopatic hbv mutations that cannot be control with any medication leading to cancer and cirrhosis despite hbsag negative, hbvdna undetectable and normal ast-alt, another reason not to use lamivudine is that it is even totally useless on hbv
the hbsag of the virus mutates to a form where the virus destroy cells directly even without replication
hbv cure is achieved only by sequen
But your baby should receive the first dose of the standard 3 dose Hepatitis B vaccine after birth. The vaccination is recommended now for all babies.
Lamivudine is effective, but has a very high drug resistance rate. If your viral load (hbvdna) has not decreased to undetectable in 6 months, you should talk to your doctor about switching to Tenofovir or Entecavir before Lamivudine drug resistance developed.
Exercise is very good, so is a healthy and balanced diet.
I was initially placed on lavumidine (lamdek) but stop to continue after the last dose ends. I went to the hospital for check up and the doctor did not prescribe any drug for me. My LFT is indicating that my values are within the cut-offs but I am afraid if I do not continue with a very effective drug, my condition may worsen. Having stopped the lavumidine for about two months, I don't if I can go back it or change a different drug. Please, I need help. what should I do now?
My regimen was Zidovudine+Lamivudine+Aluvia, bid. however, on the second day after my first dose, I missed one dose that night, and on the next day , I continued to take the regular dose. I mean , on the first day, I took regular dose, 12h, bid. on the second day, I only took the morning dose, and missed the evening dose, on the third day I took the regular dose. and from then on, I completely finished the 28 days regimen.
In the first 3 years, I took Lamivudine + Hepsera. Recently I have eaten Lamivudine + Tenofovir. Now my HBsAg (Abbott Architect - Quantity) is reduced to 3.92. It is really good to hear that I probably get serocoversion.
I am in Vietnam now. I have been with Ms. Thuy - Ph.D - in Medic Ho Chi Minh City for all the treatments. She is really a great woman. She have studied a lot about liver and got many experiences in Hepatitis disease treatments. She has been in the States many times too.
She has also been a patient of anemia.For the last 1.5 years she has been on lamivudine 100 after her hbv dna crossed 86 lacs. iu/ml in 2012.So far everything has been fine,the liver enzyme levels(AST/ALT/ALP) have nearly normalized,platelet count has increased.But one day ago she underwent a blood test and found that:Sgpt=206,Sgot=131,Alk. phosphatase=88,serum bilirubin total=0.9...While alk.
Without taking any drugs, viral load was 22,000 in september 2009. 46,000 in december 2009. Doctor recommended lamivudine in January. Took lamivudine and by June 2010, viral load was undetected. have read in many forums that lam is not the best, approached my doctor with this concern and she sugessted tenofovir. Should i start tenofovir immediately, how should i start. Should i just abruptly stop lam and move on to tenofovir, should i use both and gradually stop lam after a few day/weeks.
Hepatic decompensation was not prevented by lamivudine compared to placebo or entecavir compared to lamivudine in three underpowered trials.
Hepatocellular carcinoma was not prevented in four studies with inadequate size and duration. In one RCT, analysis that adjusted for country, sex, baseline ALT level, Child-Pugh score, and Ishak fibrosis score and excluded five individuals who developed HCC within the first year of the study found a borderline significant effect of lamivudine.
10.300 copies/ml . I got lamivudine 100 mg /day vitamine E 4oo ui /day, orange juice everyday 50 cc/day ,and others fruits,2 months later my blood test showed DNA/HBV/PCR negative (<200 copies ),checked regularly every 3 months untill now still negative level. SGPT 75- 90 ui/ml constantly,never down a normal range,since 2008 March untill now. HBsAg negative level ,HBsAb negative level ,others test are normal levels .Is i got recovery from Hepatitis B ?
I have tested positive to Hbsag for more than a year now. I was placed on lamivudine, methionine and essential forte. d doctor never ask me to do viral load test anytime I see him he do ask me to do LFT and subject me to d early medications I listed. so a friend advice me to go teaching hospital were I can see a specialist. my question here is now that I have been on medication for a year without knowing my viral load what is d implication ?
I am a 26 year old male having hbsag and hbeag=+ve,hbv dna =1070 iu/ml(Taqman) but my LFT results are normal(sgpt=37,sgot=33).My doctor has asked me to take lamivudine 100 mg for 6 months or until hbv dna becomes -ve.My mom is taking lamivudine for the last 7 months after her hbv dna crossed 8 lacs iu/ml.Probably I have been infected from my birth.Is it possible for both of us to completely cure Hep. B after taking lamivudine.
1. I am HBV carrier, and I am also under treatment with taking lamivudine 100mg daily. Will this impact the result? Will lamivudine/HBV virus cause false negative?
2. Because I am taking lamivudine daily, will this cause the delay of seroconversion. I think the test was done about 18 months after events that I thought maybe risky.
3. My test is Combo TypeI/II antibody and p24 antigen QUAL CMIA. Is it reliable?
4. My HBV DNA level is sometimes undetectable, but sometime a few hundreds.
I am a 26 year old male having hbsag and hbeag=+ve,hbv dna =1070 iu/ml(Taqman) but my LFT results are normal(sgpt=37,sgot=33).My doctor has asked me to take lamivudine 100 mg for 6 months or until it becomes -ve.My mom is taking lamivudine for the last 7 months after her hbv dna crossed 8 lacs iu/ml.Probably I have been infected from my birth.Is it possible for both of us to completely cure Hep. B after taking lamivudine.
I was examined by my first doctor and advice me that I am not qualified for medication but my employment requires to pass this Hepa B case so I look for another doctor that could give me something for medication.. The doctor and give me Lamivudine(Zeffix)..
My question is; Is there someone in this forum that had experience with this level of UI/ml that been cured and how long?.. My employeer is waiting for my respond but I cant give them exact or approximate date when will cured..
Epivir=Lamivudine, said to be very safe for husband and wife who wish to have children. But do you have to choose Lamivudine as first-line treatment with its high resistance profile?
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