To measure cough reflex sensitivity, capsaicin cough challenge testing was performed 1 month prior to cessation of therapy,
and 1
and 2 months after completion of treatment. In all patients,
cough reflex sensitivity, as measured by C(5) , the concentration of capsaicin inducing 5 or more coughs, was significantly enhanced during treatment compared to 1 month after completion of therapy (P = 0ยท016).