I have CML and was treated with Gleevec for 4 years and achieved remission. I have for the past several months been experiencing sudden onset of weakness which last for hours, to days. My blood pressure which has remained under control for several years with atenolol has been running 145/105 and higher for the past three to four months. I have a feeling of fullness in my stomach, and I have sporatic episodes of mild coughing, this occurs maybe once a week.
Hi, I don't know the answer -- but since both CML and Gleevec toxicity produce anemia because of marrow suppression, maybe it's not possible to tell the difference. E.g., both would show a low reticulocyte count.
This full text paper on anemia from Gleevec https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.23879 shows that other signs such as red blood cell size can vary, so that doesn't seem to help. Sorry.
Is it possible that after taking gleevec for only two weeks WBC droped from 36.7 to 7? All other blood counts are also came back to normal range. Could doctor make mistake in diagnosis of CML? Maybe I should get seg second opinion?
I was diagnosed with CML and given Gleevec 400 ml. After taking gleevec for 2 weeks doctor took additional blood test. My WBC dropped from 36.5 to 7.1 and all other blood counts came down to normal range. I'm wondering if gleevec could give such fast hematological response or I was possibly misdiagnosed originally. I don't and didn't have any symptoms, my spleen and liver weren't enlarged, no enlarged lymph. Should I get second opinion asap? Please, help me.
After two weeks on 400mlg gleevec my WBC droped from 36.5 to 7.1. My doctor told to come for additional test in two weeks. Now my WBC is 1.3 and absolute neutrophils count is 0.04. I was told to stay home on antibiotics. How long it may take for my counts to clime back to safe range. And of course, I'm off gleevec right now. Does it seem that dose of 400mlg is too high for me.
i was diagnosed with cml in march of 2009 and was also taking 150mg of elavil at bedtime to control migraines for like 10 years. then this past dec. a heart test showed i had prolonged qt of the heart so i was stopped 'cold turkey' by a dr and its been down hill ever since. i have had the shakes, loss of appetite and constant nausea. i wake up evey morning shaky really bad.
Am on Gleevec 400mg, now having problems with blisters on the palm. What can I do about it?
I was diagnosed last year and was immediatley put on gleevec 400mg/day.At my last consult my metabolic stats had risen,hence blood tests to determine if the gleevec is no longer working.I am still in firstphase and wonder what my options are if the gleevec is no longer an option.Amin pretty good form,just very tired and a lot of bone pain.
You might find he starts to be able to tolerate the pill. Gleevec is first choice for treating CML, and if he is doing good in every other way then encourage him that he is doing great.
I hope this helps you. I would be glad to help you with any other questions.
My Patty was diagnosed with Heart Failure 10 days ago, he had been doing pretty good, not liking taking his meds but now he is NOT wanting to eat and when we make it liquid and squirt it down his throat, it has started coming back up. He has no problem drinking and peeing. He is a month over 15 years old and my precious baby. Any ideas out there, he goes back to his dr in 2 days but I am about sick, his mom died of kidney failure and I hate to think this is happening to him.
Those aren't the signs of ecstasy and certainly after a period of 2 months, the drug would be completely out of your system. I would go and have some blood tests to see what is going on.
I now have many of the long term complications. The one that is most difficult is heart failure, specifically diastolic heart failure. I would like to communicate with others who are dealing with this to see if they experience the same issues that I do. I was diagnosed with this heart condition 5 years ago, and have had a triple bypass 2 years ago. The problems result from the interaction of the heart condition with my diabetes. Your response would be greatly appreciated.
There are doctors forums where you can ask an expert your question. If you go to the top where it says forums pick Doctors Forums. This forum is generally attended by patients only. You should also probably seek out a doctor in your area to go see to be evaluated in person. That said, palpitations don't necessarily mean anything. the heart has to be evaluated to know exactly what it is you are feeling and if what you are feeling is dangerous to your heart.
You really need your doctor to give you an explanation about your report. Your report indicates that a portion of your heart is not beating properly and your heart is not pumping efficiently. Did your report give an ejection fraction (EF%) by chance? That would help.
In any case, no one here is qualified to tell you the implications of your report, please see your doctor.
I have health anxiety so I’m terrified I have heart failure. She said it’s asthma But my Inhaler doesn’t help and my breathing treatment only brought me from 73% to 75% on my lung function test. She did an ekg and it came back abnormal saying I have horizontal axis for age and Abnormal precordial QRS contours-nondiagnostic for this age. She literally said “I don’t know what that means but if you have heart failure you wouldn’t be able to breathe when lying down.
No one here can possibly tell you its okay for your friend to take a non-prescribed opiate. He needs to ask his doctor about this. Good luck.
Hi all,
Before I start, I should state that I am not looking for a diagnosis here, it would be idiotic of me to even think about asking for one given that no one here knows my medical history.
What concerns me is this - for the last couple of years, I have been having spells of tachycardia and now have a resting heart rate of 110-130bpm. This constant tachy state leaves me tired and breathless.
Heart failure indicates the heart is not pumping enough blood/oxygen to meet the systems demand. If the heart failure is due to heart muscle damage from a heart attack, muscle disease, etc., the condition may not get any better but can be controlled with medication and reduce any progression.
Sometimes, as in my case, five years ago I had ischemiac (lack of blood flow) from occluded vessels and a silent heart attack. The heart cells were stunned and impaired the contractions (EF 13-29%).
Recommended
