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Gleevec and heart

Common Questions and Answers about Gleevec and heart

gleevec

Avatar n tn Hi, I don't really know the answer but if you are getting reduced white-blood-cell counts, then I'd especially want to avoid any food with possible bacteria. Maybe Mocha can say more. Also, since a few patients get heart damage, I'd look into possibly using melatonin and Co-Q10 (OTC supplements) to try and prevent that. I'm not a big fan of alternative treatments for cancer, but I think that a few things do have value.
Avatar m tn I have CML and was treated with Gleevec for 4 years and achieved remission. I have for the past several months been experiencing sudden onset of weakness which last for hours, to days. My blood pressure which has remained under control for several years with atenolol has been running 145/105 and higher for the past three to four months. I have a feeling of fullness in my stomach, and I have sporatic episodes of mild coughing, this occurs maybe once a week.
Avatar m tn Hi, I don't know the answer -- but since both CML and Gleevec toxicity produce anemia because of marrow suppression, maybe it's not possible to tell the difference. E.g., both would show a low reticulocyte count. This full text paper on anemia from Gleevec https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.23879 shows that other signs such as red blood cell size can vary, so that doesn't seem to help. Sorry.
Avatar n tn I was diagnosed with CML in May with WBC at 222 and an enlarged spleen. Currently on Gleevec 400mg and the last FBC shows WBC at 2.1 . Still maintaining current dose of 400mg.Apart from some annoying blisters on my palm, other side effects rather acceptable.
Avatar n tn I was diagnosed with CML and given Gleevec 400 ml. After taking gleevec for 2 weeks doctor took additional blood test. My WBC dropped from 36.5 to 7.1 and all other blood counts came down to normal range. I'm wondering if gleevec could give such fast hematological response or I was possibly misdiagnosed originally. I don't and didn't have any symptoms, my spleen and liver weren't enlarged, no enlarged lymph. Should I get second opinion asap? Please, help me.
Avatar n tn t want to see me, that fever was not from gleevec, and that I needed to monitor myself by myself by simply taken ibuprofen. This is what I did all last week and only this Monday he did a blood work. For now, what can I do to help my body to build my immune system back? Any vitamins? I'll appriciate any advice.
Avatar f tn If a person had a *very* severe long QT, they might be given intravenous calcium to counteract that. That's because Calcium is an excitatory chemical. And guess what? Gleevec can cause low levels of calcium. So maybe both drugs together resulted in your problem with the long QT. The offshoot is that if you ever were to go back on a higher dose of Elavil, you might want to make sure you get enough calcium. But that would only be with a doc's say so, of course.
Avatar f tn I was diagnosed last year and was immediatley put on gleevec 400mg/day.At my last consult my metabolic stats had risen,hence blood tests to determine if the gleevec is no longer working.I am still in firstphase and wonder what my options are if the gleevec is no longer an option.Amin pretty good form,just very tired and a lot of bone pain.
Avatar n tn You might find he starts to be able to tolerate the pill. Gleevec is first choice for treating CML, and if he is doing good in every other way then encourage him that he is doing great. I hope this helps you. I would be glad to help you with any other questions.
Avatar m tn only take 25 mgs of toprolXL daily... and thats it..I had my heart ablation performed at the Heart of Hospital of Austin in Austin, Texas and only had to wait about 3 months.. they were great and have the reputation of being the best heart hospital in the South West...
225036 tn?1294509400 Just know I am thinking of you and keeping you in my heart and in my prayers. You have fought a good fight and I know you will do your best to continue.
1004138 tn?1316251113 No there is no herbal treatment for CML!!! Were you diagnosed with CML, and if so are you seeing a specialist and what treatment are you on.? I am being treated for CML, and was told not to even drink herbal teas well on my medication. Share some more information so I can help you. I have had CML for 13 years.
Avatar f tn She had an abcess in her gums/jaw bone that went undiagnosed for more than a year but that was 4 years ago and I wondered if that led to infection around the heart which I read could happen, but I assume they would have checked for that. If you had a case like this that you ruled out everything but CML and called her a one in a million case that is atypical, what would you have checked for before giving it the atypical ruling? I could then ask if those things were checked for.
Avatar n tn I am a Leukemia Survivor also. What type of Leukemia did you have, and what was your treatment. I have CML, and have achieved a major molecular response through a oral chemo drug called Gleevec. It does not sound like these patches have anything to do with the Leukemia. I would see a Dermatologist to have them evaluated. I hope that helps you a little bit.
Avatar n tn * buprenorphine Metabolized into norbuprenorphine by cytochrome-P450 isoenzyme 3A4 * Tyrosine kinase inhibitors, including Gleevec and Tasigna, used to treat chronic myelogenous leukemia and gastrointestinal tumors.
Avatar m tn I was diagnosed w/CMML in 2009 and did 6mos of Vidaza. Monocyte levels keep rising and are now at 28%. 54 yr old male. My drs. just keep telling me to watch and wait, but I don't feel comfortable doing that, especially since I am fighting a recurrent staph infection that keeps returning every month.
962875 tn?1314210036 heart drugs, antifungal agents, analgesics and even antihistamines such as diphenhydramine (Note that the accompanying Table includes only those drugs with substantial inhibition of CYP2D6. Many other drugs are moderate to weak inhibitors of CYP2D6, and, depending on the dose of the drug, they could potentially inhibit the conversion of tamoxifen to its active forms.) . Table 1.
374668 tn?1214338737 Probably not; I've had one since I was 2 years old. Though I used to worry all the time about it... and Dr's still want to send me for tests each time I see a new one. I've had echos done a few times and never find anything... I was told my heart was normal and wouldn't get worse. My murmur can get really loud if I'm anxious or nervous or after exercise... then sometimes can barely be heard when relaxed. Yours sounds like mine...
148588 tn?1465778809 Louis and the founder of Rare Genomics, a nonprofit organization that designs treatments for rare childhood diseases based on individual genetic analysis, “we have drugs that target specific cancer mutations. Examples include Gleevec, Zelboraf, and Xalkori. Vertex,” a pharmaceutical company based in Massachusetts, “has famously made a drug for cystic-fibrosis patients with a particular mutation. The genetic targeting of individuals is a little farther out.
Avatar f tn I have been having problems with my heart rate and beat. It goes very fast and then goes very slow. I have a lot of irregular beats and now my cardiologist wants me to do an ablation but I am convinced that something else is causing this. I have just gotten my thyroid levels checked and they are fine. So should I get my adrenal glands checked? I really know that all my symptoms are not from my heart.
Avatar n tn I am 32 years old man , having problem of stress and tension since 3 years my BP is used to be 130/86 most of the time , one day befere 15 days I felt needle like pain in left chest i went to doc and he took ECG and said that there is small change in one lead and that is due to anxiety or MVP After that I used to be tensed all the time regarding my heart and that cause me pain like feeling (not exactly pain ) and my confidence is getting low.
Avatar n tn Dear all Please suggest if needle like pain in chest also a symptom due to anxiety I got and ECG and lot of heart rate found there , doc say there are changes in one lead and that could be due to Anxitety(99%) or MVP.
Avatar f tn And how closely are your heart and lungs related over the past year also found out I have mitral valve prolapse and had costcondritis(i think thats how u spell it swelling of the heart walls)just wondering if ALL this could be related?