Gleevec bladder cancer
Common Questions and Answers about Gleevec bladder cancer
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The last thing anybody would want is to stop the Gleevec, which is a wonder drug of anti-cancer treatment. So we must think of "managing" the hyponatremia problem.
I haven't found anything about long term use of Gleevec. But what springs to mind is that she might have started some other drug recently, which is turning mild hyponatremia to severe hyponatremia. Even ibuprofen. Has she?
I was diagnosed last year and was immediatley put on gleevec 400mg/day.At my last consult my metabolic stats had risen,hence blood tests to determine if the gleevec is no longer working.I am still in firstphase and wonder what my options are if the gleevec is no longer an option.Amin pretty good form,just very tired and a lot of bone pain.
Hi, I don't know the answer -- but since both CML and Gleevec toxicity produce anemia because of marrow suppression, maybe it's not possible to tell the difference. E.g., both would show a low reticulocyte count.
This full text paper on anemia from Gleevec https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.23879 shows that other signs such as red blood cell size can vary, so that doesn't seem to help. Sorry.
Is it possible that after taking gleevec for only two weeks WBC droped from 36.7 to 7? All other blood counts are also came back to normal range. Could doctor make mistake in diagnosis of CML? Maybe I should get seg second opinion?
I was diagnosed with CML and given Gleevec 400 ml. After taking gleevec for 2 weeks doctor took additional blood test. My WBC dropped from 36.5 to 7.1 and all other blood counts came down to normal range. I'm wondering if gleevec could give such fast hematological response or I was possibly misdiagnosed originally. I don't and didn't have any symptoms, my spleen and liver weren't enlarged, no enlarged lymph. Should I get second opinion asap? Please, help me.
After two weeks on 400mlg gleevec my WBC droped from 36.5 to 7.1. My doctor told to come for additional test in two weeks. Now my WBC is 1.3 and absolute neutrophils count is 0.04. I was told to stay home on antibiotics. How long it may take for my counts to clime back to safe range. And of course, I'm off gleevec right now. Does it seem that dose of 400mlg is too high for me.
Am on Gleevec 400mg, now having problems with blisters on the palm. What can I do about it?
I have CML and was treated with Gleevec for 4 years and achieved remission. I have for the past several months been experiencing sudden onset of weakness which last for hours, to days. My blood pressure which has remained under control for several years with atenolol has been running 145/105 and higher for the past three to four months. I have a feeling of fullness in my stomach, and I have sporatic episodes of mild coughing, this occurs maybe once a week.
You might find he starts to be able to tolerate the pill. Gleevec is first choice for treating CML, and if he is doing good in every other way then encourage him that he is doing great.
I hope this helps you. I would be glad to help you with any other questions.
I am not a doctor but have undergone treatment for bladder cancer. Standard procedure among urologists for early stage bladder cancer is inserting BCG into the bladder once a week for six weeks and/or mitomycin treatment after tumor removal.
There is no shortage of either of those drugs.
Ask your doctor about them.
I'm a 43 year old man with the cancer mutation lynch syndrome msh2 and a strong family history of colon cancer my 41 yo brother,cousins and uncles, pancreatic and my mother had Glioblastoma of the Brain at age 68.Recently I had a cytology and cystoscope which found tumors in my bladder.
I suffer from ulcerative colitis and now diagnosed with superficial bladder cancer (Ta, low grade). My bladder was perforated during tumor removal (TURBT) resulting in colitis flare up and bowels shutting down after exposure to leakage. Now offered biological therapy (BCG) treatment and worried that the expected stimulated immune response will trigger another colitis "attack".
Thank you.
i get my heart checked every 2 weeks now and i am fine with the qt thing. i take the chemo pill called gleevec and have to force myself to eat so i dont get sick when i take it. how long will these withdrawel problems go on? i have xanax to take (1mg) but dont work to good. i should would appreciate any advice from any one on how to deal with these issues, family dr says its anxiety but i think its the withdrawels from the high dose of elavil.
In 2007, I was diagnosed with bladder cancer, via a FISH urine test. A biopsy of the bladder tissue was done in a bid to confirm or refute the diagnosis. The result of the biopsy was negative; however, every time the FISH urine test was repeated, it showed cancer cells associated with the bladder.
I asked for treatment, but was told that BECAUSE the location of the cancer was not established, treatment could not be offered. Instead, I submitted to a cystoscopy every six months.
He was diagnosed with bladder cancer about 3 years ago and had his bladder removed. There didn't appear to be any spread of the cancer outside the bladder. Two months later they discovered cancer in his uretha and removed that. Since then, he had had severn clean checkups with no further evidence of cancer. This past fall, he started having sever back pain. This was treated with an orthapaedic specialist until March.
My good friend was diagnosed with Stage 1 bladder cancer 6 months ago. He was told that the cancer had not reached the muscle of the bladder. They removed the tumor and gave him 6 weeks of the BCG treatment. Soon after finishing the treatments he started peeing blood again so he went back in to find that a golf ball sized tumor had grown back during the treatments.
IF the FISH is negative, we’ll now you don’t have cancer, but it would be prudent to monitor as the findings may mean pre-cancer. Attempting to remove the bladder now to prevent conversion of pre-cancers into cancers is not recommended because a good number of these so-called pre-cancers do not become cancers within the span of a human lifespan.
Hope this helped.
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