gleevec and pancreatic cancer

I was diagnosed last year and was immediatley put on gleevec 400mg/day.At my last consult my metabolic stats had risen,hence blood tests to determine if the gleevec is no longer working.I am still in firstphase and wonder what my options are if the gleevec is no longer an option.Amin pretty good form,just very tired and a lot of bone pain.

Hi, I don't know the answer -- but since both CML and Gleevec toxicity produce anemia because of marrow suppression, maybe it's not possible to tell the difference. E.g., both would show a low reticulocyte count. This full text paper on anemia from Gleevec https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.23879 shows that other signs such as red blood cell size can vary, so that doesn't seem to help. Sorry.

I was diagnosed with CML in May with WBC at 222 and an enlarged spleen. Currently on Gleevec 400mg and the last FBC shows WBC at 2.1 . Still maintaining current dose of 400mg.Apart from some annoying blisters on my palm, other side effects rather acceptable.

I was diagnosed with CML and given Gleevec 400 ml. After taking gleevec for 2 weeks doctor took additional blood test. My WBC dropped from 36.5 to 7.1 and all other blood counts came down to normal range. I'm wondering if gleevec could give such fast hematological response or I was possibly misdiagnosed originally. I don't and didn't have any symptoms, my spleen and liver weren't enlarged, no enlarged lymph. Should I get second opinion asap? Please, help me.

//www.webmd.com/cancer/pancreatic-cancer/causes-pancreatic-cancer Symptoms of pancreatic cancer are found at this link. https://www.webmd.com/cancer/pancreatic-cancer/pancreatic-cancer-symptoms#1 When they speak of light stools they are speaking in terms of jaundice which usually has other symptoms such as yellow skin or eyes. Do you have that as well? If not, I'd not necessarily associate light stools with pancreatic cancer. GERD is likely to cause yellow stools.

What is the best exam to rule out Pancreatic Cancer? I´ve been expericieng some problems in the last month: my stools are different, vague low abdominal pain and vague back pains. I am very anxious. After read about Cancer Pancreatic I can´t put my mind at rest and started feeling minor itches. My doctor asked a ultrasound and some blood tests. After the results he said it is fine for Pancreas. But I have other problems: 2 stones in my gallblader and minor hepatic steatosis.

I have a friend that is sick with pancreatic cancer I don't know what kind he has. I don't know if it's exocrine or endocrine but what I would like to know is what is the survival rate for individuals with this type of cancer. However age, race, gender all of that play a part.

I am very sad. Just got a call from my dad saying he has pancreatic and liver cancer. From what I recall its an aggressive cancer right? He hasn't been dx with hep c. I don't have very much info at the moment. Waiting for them to call me after appointment.

OTOH, an antioxidant substance like melatonin might actually enhance the cancer-killing power of the drugs used in ovarian cancer, and it possibly reduces adverse effects of other drugs (like doxorubicin) without reducing their cancer-killing power. Everything needs to be individually researched.

Doctor feels CT Scan is enough to rule out Pancreatic cancer as blood and urine is normal, That having pain something would have shown on CT Scan with pancreatic CA.

t want to see me, that fever was not from gleevec, and that I needed to monitor myself by myself by simply taken ibuprofen. This is what I did all last week and only this Monday he did a blood work. For now, what can I do to help my body to build my immune system back? Any vitamins? I'll appriciate any advice.

The exact cause of pancreatic cancer is unknown but it is more common in people with diabetes, people with long-term inflammation of the pancreas or smokers. Early symptoms of pancreatic cancer include dark urine and clay-colored stools, fatigue and weakness, jaundice or yellow color in the skin, mucous membranes, or eyes; loss of appetite, upper abdominal pain, weight loss and even nausea and vomiting.

H Pylori thrives in low stomach acid and lowers stomach acid further. Low levels of stomach acid (stomach acid stimulates the pancreas to release enzymes to help with digestion just to add) can also cause malabsorption and floating stools. There are many possible symptoms from not enough stomach acid. My mother takes betaine HCL with pepsin supplements to increase stomach acid and digestive enzyme supplements to help with digestion. I'll send you a few article with more info.

Constitutional symptoms such as unexplained weight loss, fevers, chills, and night sweats are always concerning and merit further workup to rule out cancer, infection, and/or other pathology.

I am also having upper and lower back pain. I have an ultrasound scheduled for next week. I had liver blood test done and all things were normal. My questions are: If it was pancreatic cancer, would there abnormal liver enzymes? If back pain was from pancreatic cancer, would there also be other symptoms like jaundice, weight loss, nausea/vomiting or can back pain alone be cause for concern?

Hi I went to the doctor 3 days ago because my testicle hurt he examined it and said it was normal and didn't feel any cancer. But I was worried that it had spread and read about pancreatic cancer and I am freaking out scared. I know you don't survive if you get it and its really hard to detect it untill its too late. I am 30 my last blood test f was 6 too 7 months ago for a cbc and urine test and the other blood test that checks Cholesterol and Triglycerides my sugar levels I think.

These types of ascites are typically manifestations of advanced cancers of the organs in the abdominal cavity, such as, colon cancer, pancreatic cancer, stomach cancer, breast cancer, lymphoma, lung cancer, or ovarian cancer. Pancreatic ascites can be seen in people with chronic (long standing) pancreatitis or inflammation of the pancreas. The most common cause of chronic pancreatitis is prolonged alcohol abuse.

Also had a spot come up on my ankle that looked like blood pooled under skin after umerious trips to the ER thinking I had blood clots they said maybe superficial blood clot. I read that that can go along with pancreatic cancer. had abdominal ultrasound a year ago that was fine. blood work has been fine. any ideas?

While it is uncommon to have concomitant cancer, there is a research from the University of Chicago Medicine that shows a strong link between pancreatic cancer and the BRCA2 mutation that plays a role in breast cancer. (ref: http://www.uchospitals.edu/specialties/cancer/pancreatic/genetics.html) . Hope this helps. Take care and best regards.

Hello and hope you are doing well. Any structural abnormalities of the gall bladder like stones or polyps need surgical correction. The stones can chronically irritate the gall bladder wall and cause inflammation and pain. Also, this chronic irritation is a predisposing cause for gall bladder cancer. If the stone is placed in the neck of the gall bladder, it can cause retention of bile, with stasis and consequent infection. So, the best option would be to have an elective gall bladder removal.

Read about pancreatic cancer and I am freaking out scared. My best friend dad died from this 2 years ago.I know you don't survive if you get it and its really hard to detect it untill its too late. I am 31 my last blood test was 1 year 7 months ago for a cbc and urine test and the other blood test basicaly a physical.that checks Cholesterol and Triglycerides my sugar levels I think. Doctor didn't call me back so everything must have come out okay.

Gleevec and pancreatic cancer

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