i have never taken wellbutrin but my daughter does, i have taken
effexor. for me the
effexor was terrible, but some people on this site do very well with it. it made me extremly tired, heart palpitations, raised my blood pressure, jaw pain and many other problems. my daughter says the wellbutrin helps her depression but makes her anxiety worse so if you have anxiety you may have to take something for that on top of the wellbutrin. in my opinion, effexor is horrible, i hated it.