Ribavirin manufacturer
Common Questions and Answers about Ribavirin manufacturer
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Metavir A3/F3 means you have severe liver inflamaton and septal fibrosis or advanced liver disease stage 3 which is one stage below cirrhosis.
You are from Kenya and the most common genotype is 4. Currently, they are treating that genotype with interferon and ribavirin as well as genotype 2 & 3. If you are genotype 1, the standard of care is triple therarpy using a protease inhibitor, either Victrelis or Incivek in conjunction with interferon and ribavirin.
I have been thinking about the Ribavirin we have been ingesting over the many months of treatment and Who has had the Brand products and Who has had the Generic brands?
I had taken the generic brand Zydus for the first 9 months of treatment which had changed from a capsule form to a pill form and the last 3 months with Sandoz in a pill form. It would be interesting to see who has been taking what over the course of treatment.
1.
Telaprevir alone will probably cost around $25,000. Then you also need peginterferon and ribavirin - another $20,000 (if treatment is only 6 months). Then you need medication for side effects ($5000), many lab tests ($2000), and doctor exams ($1000). The entire cost for hepatitis C treatment can easily be over $50,000.
A hemopurifer will not cure the disease. Viral load being high or low really has nothing to do with the amount of liver damage a person has at all so relatively if you were able to "clean" some out of your blood you would still have the disease just exactly the same.
The only cure that works is the current treatment of interferon and ribavirin.
Sorry.
Ribavirin Pregnancy Warnings
Ribavirin has been assigned to pregnancy category X by the FDA. Nearly all animal studies have revealed evidence of embryolethality and teratogenicity. There are no controlled data in human pregnancies. One published case reports the uneventful use of ribavirin at 33 weeks gestation. Ribavirin therapy is contraindicated in women who are pregnant and in the male partners of women who are pregnant.
Most of the concerns raised about ribavirin's teratogenicty is a result of experimental animal tests. Ribavirin has been found to be teratogenic and/or embryolethal in several species of animals: in hamsters, ribavirin was associated with defects of the limbs, eyes, and brain; in rats, defects of the brain and eyes predominated -- but these were experiments exposing bone marrow cells.
My understanding is the active ingredient of each is the same, but just a different brand name by different manufacturer. I recall some are available in different doses, so if you needed to do a dose reduction this could be an advantage.
Decided to start treatment next week though, bygetting interferon shot every Friday, and I am travelling this Saturday. I have only noticed that Ribavirin capsules that pharmacy gave me for 3 months have expiry of October 2014. If I start taking drugs on 15 August, it means 3 packs of Ribavirin will become expired during my treatment, as I will take them till November 15. Should I request pharmacy to change portion of packs?
yes I think I have ascites now, not on Rbavirin and yes taking water pills,60mg furosemide and 50mg spironolactone a day
I think almost all patients are given daily ribavirin pills in addition to the weekly subcutaneous injection of interferon, and for the more resistant genotypes they will usually add one of two different protease inhibitor drugs as well. All these drugs are pretty expensive if you have to pay full price, but most people either have insurance that covers all but a co-pay, or find some kind of assistance with the costs.
Harvoni plus Ribavirn for 24 weeks or Daclatasvir plus Sofosbuvir and Ribavirin 24 weeks? I am genotype 4 liver cirrhosis F4 relapsed on Sovaldi and Interferon and Ribavirin.
They are actually very helpful and have covered the costs of many peoples medication, both the copegus( ribavirin) and the pegasys(peginterferon-alfa-2a) which are used to treat Hepatitis C. They are connected to the manufacturer,Roche.
Hope the info helps.
While there is very little data available (only form very small studies- 10 or less patients) about the improvement of SVR rate over peg-interferon and Ribavirin, it is assumed that SVR rates are higher than with the 2 drug treatment. The SVR rate using only peg-INF and RBV among post transplant patients is only 30%.
The issue with triple treatment is the amount and degree of adverse events and side effects are worse then with just 2 drugs.
If the premixed interferon has been allowed to warm to room temperature for an extended period, you should probably call the manufacturer and request a replacement. Roche Pharmaceuticals maintains a toll free hot line; give them a call and discuss your situation with them.
I believe proteins in the medication can ‘denature’, possibly affecting treatment outcome.
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