Ribavirin half life

Common Questions and Answers about Ribavirin half life

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1084115 tn?1385228589 The mean half-life for multiple doses in the body is about 12 days, but very long-term kinetics are dominated by the kinetics of RBCs (half-life 40 days). RBCs store ribavirin for the lifetime of the cells, releasing it into the body's systems when old cells are degraded in the spleen.
Avatar m tn i hear taking ribavirin with a source of fat helps the absorption, many would agree with this statement. however, not sure if this has much of an effect on the half life of ribavirin and thus the Interferon.
Avatar n tn Ribavirin has a longer half life than interferon. The levels for both gradually come down to zero over time. It is a few weeks with interferon and a few months with ribavirin.
Avatar m tn Significant teratogenic and/or embryocidal effects have been demonstrated in all animal species exposed to ribavirin. In addition, ribavirin has a multiple dose half-life of 12 days, and it may persist in non-plasma compartments for as long as 6 months. Ribavirin therapy is contraindicated in women who are pregnant and in the male partners of women who are pregnant..." http://www.druglib.
Avatar m tn the half life of ribavirin is 12 days - Multiple Dose; 120-170 hours - Single Dose. Ribavirin will also stay in your body for up to six months after tx because it is stored in your red blood cells and as the blood cells degrade it is was again released. The only reason we take two doses of ribavirin is because it can cause gastro issues for some.
Avatar f tn The half-life of a drug is how long it takes for half of it to be eliminated from the bloodstream. Hope that helps.
6298176 tn?1380134459 It has a very long half life, though I can't give you specifics. The dose and how long you were on it does factor in. Your doctor should be able to help you with your questions on this.
Avatar f tn The volume of distribution of ribavirin is large (2000 L/kg) and the length of time the drug is trapped varies greatly from tissue to tissue. The mean half-life for multiple doses in the body is about 12 days, but very long-term kinetics are dominated by the kinetics of RBCs (half-life 40 days). RBCs store ribavirin for the lifetime of the cells, releasing it into the body's systems when old cells are degraded in the spleen. http://en.wikipedia.
3093770 tn?1389739126 s long half life. The rule of thumb for dosing ribavirin is usually 12 hrs apart but taking it with your evening meal is fine plus the fat grams will help with absorbency. If you choose to take it at 10 pm and it does not interfere with your sleep than stick with it because that's what works for you.
4705307 tn?1447970322 com › Drugs A to Z › Ri‎ In addition, Ribavirin has a multiple dose half-life of 12 days, and it may persist in non-plasma compartments for as long as 6 months. The Riba in combination with the Pegasys Inf, makes the half life of the Inf extended though...You should ask your Doctor, and there is also some good threads on here about.
Avatar f tn Ribavirin has a multiple dose half-life of 12 days, and it may persist in non-plasma compartments for as long as 6 months. Therefore, Ribavirin, including Ribavirin tablets, is contraindicated in women who are pregnant and in the male partners of women who are pregnant. Extreme care must be taken to avoid pregnancy during therapy and for 6 months after completion of therapy in both female patients and in female partners of male patients who are taking Ribavirin therapy.
2080475 tn?1332126191 decided to quit taking it on a monday felt fine all week untill sun when i went into serious withdrawl! so as far as half life im not sure? but you can bet i was back on it mon! so i guess it was in my system for 6 days after i stopped. p.s.
Avatar f tn ?? Does anyone know the Half life of SUBOXONE - Beprenorphine.? I HEARD it was 70 hours, but that's what I heard....unsure if that is even accurate?
535882 tn?1396576685 whats the half life for syntriod. about how much time does it take to build up in you and also leave your system?
Avatar m tn It's an approximate computation based on the half life of ribavirin which is quite long. My guess it's probably a bit on the conservative side but why take a risk when potential birth defects are involved.
1418633 tn?1314546745 The mean half-life for multiple doses in the body is about 12 days, but very long-term kinetics are dominated by the kinetics of RBCs (half-life 40 days). RBCs store ribavirin for the lifetime of the cells, releasing it into the body's systems when old cells are degraded in the spleen.
Avatar m tn The mean half-life for multiple doses in the body is about 12 days, but very long-term kinetics are dominated by the kinetics of RBCs (half-life 40 days). RBCs store ribavirin for the lifetime of the cells, releasing it into the body's systems when old cells are degraded in the spleen.' I'll try and find the study.
Avatar m tn The mean half-life for multiple doses in the body is about 12 days, but very long-term kinetics are dominated by the kinetics of RBCs (half-life 40 days). RBCs store ribavirin for the lifetime of the cells, releasing it into the body's systems when old cells are degraded in the spleen.