This means I change from oxycodone to morphine to
hydromorphone, etc. when tolerance causes my dose to
creep up too high, too quickly..
In these last 20 years I've used these long-acting opioids: Duragesic (fentanyl) patch, OxyContin, methadone, ms contin, and Exalgo (hydromorphone), along with short acting / immediate release opioids oxycodone, hydromorphone (Dilaudid), and morphine.