However, NSAIDs cause pronounced declines in the
renal function within hours in the stressed kidney by reducing the
renal plasma flow and glomerular filtration rate, according to the National Center for Biotechnology Information. (See References 2) Furthermore, prolonged use of NSAIDs increase the risk of permanent renal damage in patients with already impaired renal function, adds the National Center for Biotechnology Information (See References 2)
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