If you are wearing several layers of varnish
and it starts lifting instead of just flaking
off it would be a prime site for an infection, most peoples varnish just flakes off and even if it did start lifting most people would just strip off the whole varnish. So the chances are pretty rare. The same cannot be said for any artificial nail systems tho, lifting falsies are prone to fungal infections.
Could you paint over an infection...yes but once again it would be pretty negligent.