I use a rx spray estradiol.But, I thought my probs were due do
estrogen dominance. (depression,facial hair growth,
acne, high cholesterol, high insulin,weight gain upper body, too much testosterone,breast cysts and probably ovarian cysts). I lost 100 pounds from a gastric bypass but am still about 50 pounds overweight. Do fat cells secrete estrogen? Do I even need estrogen replacement? I used a bioidentical progesterone cream in the past. I was on Yaz birth control before the surgery.