Hi,
Prurigo nodularis is very hard to treat, but current therapies include steroids, vitamins, cryosurgery,
thalidomide and UVB light. In the event that staphylococcus or other infection is present, antibiotics have proven effective.
A physician may administer a strong dose of prednisone, which will almost immediately stop the itch/scratch cycle. However, cessation of steroids allows relapse to occur, usually within a few weeks.