If your depression is severe, you should call the neuro that ordered the
SoluMedrol. I did not suffer depression while on it, but I did have disassociation
and knew my thinking process was out of whack. I didn't like the feeling and did not trust myself to be alone.
Everything went well, but it was scary for a while. I believe there should be better warning about the side effects and what to do about them............like call the doctor. Sorry I can't offer more info.