Simvastatin and liver enzymes

Common Questions and Answers about Simvastatin and liver enzymes


Avatar m tn "Feb. 28, 2012 -- Memory loss, confusion, high blood sugar, and type 2 diabetes are possible side effects of the popular cholesterol-lowering drugs known as statins, the FDA warns. Brand name and generic versions of statin drugs must carry these warnings on their labels, the FDA today announced.
620048 tn?1358021835 They read up on all of her meds called the Dr. he stopped the simvastatin and she is much better now and cont to improve. My husband is on it and has no problems. As with most drugs, they affect people different.
Avatar m tn Hello and hope you are doing well. Your liver enzymes are marginally elevated. They can be elevated due to fatty liver changes in the liver. This can be detected by ultrasonography. Fatty liver can be due to alcoholism when it is called Alcoholic fatty liver disease and the other one is Non alcoholic fatty liver disease, which is due to obesity, diabetes and high triglyceride levels. This can progress to cirrhosis of the liver and can be associated with hepatocellular carcinoma.
Avatar m tn check also who is making the research on simvastatin, and that liver damage has been removed recently, at least here in italy
Avatar m tn Warnings and Precautions Because simvastatin can affect the liver, it is used with caution in people who drink more than a moderate amount of alcohol or have a history of liver disease. Simvastatin is not recommended for people with liver disease or high liver enzymes before treatment begins. Possible Symptoms of Liver Problems Several symptoms can occur in someone who develops liver problems while taking simvastatin.
Avatar n tn my sister-in-law had elevated liver enzymes and couldn't think of any meds she was on that would raise her numbers. She decided to lower her consumption of diet cola thinking the aspertame might be causing probs and her numbers did go down. When my liver numbers tested higher, I also cut the aspertame and my numbers went down. Is it a coincidence or not, I don't know.
428155 tn?1203692494 I rode it out and this went away. My enzymes (Liver or muscle) have not changed since starting it about 5 months ago.
Avatar f tn I never had any issues in my blood work when i was an addict but when i started using suboxone daily for a significant amount of time my liver enzymes came back high. Like i stated earlier after quitting they were normal again and then i started using suboxone again. I recently went to the er and once again they were elevated. I have no doubt that stopping the suboxone will bring your levels down even though I'm not a professional.
907968 tn?1292625804 -- Long-term use of cholesterol-lowering statins does not increase the risk of liver disease in patients with abnormal liver function, and can actually improve liver function, according to a new study that challenges widespread belief. The researchers also pointed out that this study is the first to show that statins provide a substantially greater cardiovascular benefit in patients with abnormal liver function than in those with normal liver function. The study, published in the Nov.
Avatar m tn I have read that sometimes a switch to another type of statin can have less of an impact on liver enzymes and still adequately control cholesterol. I hope that is the case with you.
Avatar m tn all bood tests are normal since fibroguard has reservatrol which henances simvastatin potency i will lower to 40mg for a couple of days and see what happens to the back pain and then i will re-think if go to the 80mg, 60mg or 40mg dose
Avatar n tn If the increase is severe, you may need to stop taking it, which usually reverses the problem. If left unchecked, increased liver enzymes can lead to permanent liver damage. Certain other cholesterol-lowering drugs, such as gemfibrozil (Lopid) and niacin, increase the risk of liver problems even more in people who take statins. Because liver problems may develop without symptoms, people who take statins have their liver function tested periodically....." See: http://www.mayoclinic.
Avatar m tn Will I stop taking my medicine, and is taking Godex causes a rise of liver enzymes? Last May, I was diagnosed of Fatty Liver, so I was prescribed to take Godex and Simvastatin. After a month, my blood test rose from 81 U/L to 271 U/L and my SGOT which was previously normal rose to 75 U/L. My intake of simvastatin was immediately stopped due to suspected sensitivity which caused a dramatic liver enzyme elevation. I'm hoping for a decrease in the level of my liver enzymes following the LCD.
Avatar m tn My understanding is that cautious doctors get a baseline value for your liver enzymes and re-test in a month or 6 weeks to see what impact the drug may be having. Often there will be mild elevations which don't appear to cause any liver impairment but it's best to stay on top of this stuff. Sometimes, if the enzymes become elevated, a different statin can be substituted which obtains the desired cholesterol lowering without as significant an elevation in liver enzymes.
Avatar n tn Because both medicines might utilize the same pathway for activation/metabolism in the body, taking them together might result in an elevated level of simvastatin (part of vytorin) that can result in an increased risk for side effects of this medication (myositis, elevated liver enzymes, etc). If you are experiencing any of these symptoms, you should consult your doctor for further evaluation (blood work) as well as indications for lowering the dose or stopping the medicine.
Avatar m tn After clearing the virus Geno 2b in (09) and having good enzymes levels now ( AST 34, ALT 24 ) my Dr wants to increase my simvastatin from 10 mg per day to 80 mg since I have ischemic heart disease. I'm concerned about such a high dose of statins effecting my liver and I'm concerned about my heart condition. Anyone have any input for me ?
Avatar m tn Vytorin Warnings and Precautions Liver Enzymes In three placebo-controlled, 12-week trials, the incidence of consecutive elevations (≥3 X ULN) in serum transaminases was 1.7% overall for patients treated with Vytorin and appeared to be dose-related with an incidence of 2.6% for patients treated with Vytorin 10/80.
Avatar m tn Will I stop taking my medicine, and is taking Godex causes a rise of liver enzymes? Last May, I was diagnosed of Fatty Liver, so I was prescribed to take Godex and Simvastatin. After a month, my blood test rose from 81 U/L to 271 U/L and my SGOT which was previously normal rose to 75 U/L. My intake of simvastatin was immediately stopped due to suspected sensitivity which caused a dramatic liver enzyme elevation. I'm hoping for a decrease in the level of my liver enzymes following the LCD.
Avatar n tn was on lipitor for 5 months and switched two weeks ago to simvastatin in hopes of less side effects. just got some blood work done and the liver enzymes are elevated about one and a half times normal. does anyone know if its normal to see a spike in liver enzymes after switching statins or does this mean my body is rejecting the new statin?
Avatar f tn 3 HBV Genotype C Basal Core Promoter Mutation 1762, 1764 No PreCore Mutations All liver enzymes within range. No symptoms. The ultrasound results were normal with 2cm cyst on liver. My doctor recommends that I start on Viread as soon as possible. What do you think? Other questions from reading Stef2011 posts: 1. Currently on 20mg of Simvastatin. Do I have to increase to 40mg for it to be effective?
Avatar m tn I was told to avoid niacin, excess vitamin C, along with marijuana and alcohol by my liver clinic. Risk and the way liver handles excess niacin outweighed benefit though certainly getting adequate amounts by use of a NO iron multiple vitamin would be fine. Statins have so many contraindications they will probably never pass muster for liver patients.
170654 tn?1330082729 I told them it MIGHT be the Prevacid and that they needed to get checked. They got checked, and it was WAS the Prevacid. I think their liver enzymes were out the roof (like in the hundreds). But anyhow, the med was stopped, and they began feeling better within a few days, and so - I'm assuming if one is subject to get liver sick from a statin, they will know it (and that you would know, too).
Avatar m tn Simvasatin and Zolof for drugs Liver necrosis and/or liver tumor to be ruled out only with scan In the meantime simvastatin is no longer used as well as Zolof. Will try to keep cholesterol down with diet and exercise. Will run new tests in 30 ds.Do you agree?
Avatar m tn On Jan 24,2014, I cut the simvastatin to 5 mg/day and hadn't had any alcoholic beverage since then. Recently , I went to a Heptologist at Emory and he did a full liver blood workup plus ultrasound and everything was normal except the high ALT and AST. (he didn't check GGT). Nearly 4 months later, enzymes are still high. Had a few questions: 1. Is it remotely possible that the slo-niacin could be the cause and it's taking a longer than normal time for things to stabilize? Liver Dr.
446474 tn?1446351282 ) A doctor wanted to put me on statins about 3 years ago. I said no, my liver enzymes had been elevated in the past and I did not want to go on them. Plus I hate taking pills. I said let me try to lower it by diet first. He sad, "Okay, but diet change won't work." Frankly, I am not sure where he got that idea. He was young, so maybe the was too young to remember when people did modify their diets and drop their cholesterol.
Avatar n tn AST & ALT are liver enzymes that increase when there is inflammation in the liver.
Avatar m tn You say that the latest news say that low cholesterol and high vitamin D make HBV weak and improve liver healty, and I wnat to ask you a link or some information were I can read this news (studys). (I'm also a HBV carrier, recently diagnostic, and now I'm looking for the latest news ) Thank you!
Avatar m tn Effect of the Magnitude of Lipid Lowerinf in Risk of Elevated Liver Enzymes, Rhabdomyolysis, and Cancer Insights from Large Randomized Statin Trials. J Am Coll Cardiology. 2007; 50(5):409-418.) Your doctor may tell you that as long as liver enzymes are three times the level of normal, that is, a three hundred percent elevation; it is alright to continue stain use. Most patients find this to be a rather scary approach to a medication.
Avatar f tn You are prescribed a low dose which is what I am on. Same drug also. It has been a year and my liver enzymes are 18 & 17. So far so good.
469720 tn?1388149949 There are always a lot of questions about the "art" or treating cholesterol. It's a good time to refresh everyone's minds about some common guidelines. Remember that they are just that...Guidelines. Discuss the options with your physician. Most of all, remember that a health lifestyle specifically a low fat diet can reverse many of these issues. What can cause high cholesterol?