Simvastatin liver damage

Common Questions and Answers about Simvastatin liver damage

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Avatar m tn check also who is making the research on simvastatin, and that liver damage has been removed recently, at least here in italy
Avatar m tn they just used very rare cases of people that never checked alt and got these severe diseases, actually it is not even proven it was sim to do that, but in any case if you fall among the extremely rare cases where there is an alt rise you have to rethink use of sim.the rise of alt is not even proven to be liver damage....
907968 tn?1292622204 A new study published in the Journal of the American College of Cardiology examined the results of 23 large clinical trials of statins for patterns of liver damage, measured by an increased concentration of the enzymes released when liver cells die." Quote "The researchers found that high-dose statins caused 2.4 times as many cases of liver damage as low-dose statins, or 271 cases per 100,000 patients.
Avatar n tn I have been on 20 mg of simvastatin and 3000 mg niaspan now my ck levels have went from 60 to 295 i could hardly walk .will my levels come down if i lower dose. and reverse damage. i have 12 stents .the rest of my blood work is fine.
Avatar m tn the rest are just bla bla because you need a trial and a study to prove statins can make liver damage, liver experts said that even a rise in alt is not a sign of liver damage http://www.ncbi.nlm.nih.gov/pubmed/19208350 http://archive.mail-list.com/hbv_research/message/20060621.051739.d0c7de34.en.html http://archive.mail-list.com/hbv_research/message/20050605.075430.fd516aea.en.
Avatar f tn Can medications to lower high chlorestorol damage your liver, I have non-alcoholic fatty liver disease now and I am afraid to take statin drugs. How important is my concern. Simvastatin is one in particular.
Avatar m tn on the contrary studies on these cheap and generic durgs are not funded by drug makers, on the contrary we see stupid doctors without trials or studies saying now that these drugs can make liver damage while it is the opposite. only less than 1% has effects on liver and my question is how many drugs have less than 1% effect on liver..........
Avatar m tn Simvastatin is contraindicated in pregnancy and liver disease, according to Wikipedia. I also know that Cresor 40mg is not recommended for Asians. I would like to know why you believe simvastatin and or statin in geneal have ant-hbv activities? Have you heard of cases where statins cause acute liver failure in chronic hbv patients?
Avatar m tn [0010] Use of simvastatin in the prevention of malignant diseases, especially liver cancer or hepatocellular carcinoma, has been previously unknown. According to the present invention, by administering simvastatin to patients with an existing liver condition, and by monitoring the level of alphafetoprotein, a liver tumor marker, the formation of liver cancer can be prevented.
Avatar m tn I've been taking 80 mg simvastatin daily for the last 8 years, will tis be tha cause of an elevated GGT reading of over 350?
Avatar m tn check hbsag quantity and if result is less than 1500iu/ml you may clear hbv with interferon+simvastatin+vit d3+alinia (nizonide500) if hbsag is high the chances to clear are almost zero so it is better to wait and monitor liver damage by fibroscan, hbvdna has very little meaning if normal alt/ast and no liver damage by fibroscan
Avatar n tn The doctor is switching me to simvastatin which reacted badly with my liver in the past. Aim is to save money. Is it safe to buy Atorvastatin online ?
Avatar m tn sorry i think liver damage sides have little research to confirm it, it looks like sim improves liver function in cirrhosis by improving blood flow http://www.ncbi.nlm.nih.
Avatar m tn For how long will this pain be there? Is it possible that one experiences this pain, yet not have liver damage or cirrhosis. Pls advise, and if available, share real life experience.
Avatar n tn I think they are in the same drug class, I've taken both with the similar results. As I recall, I was changed from lipitor to simvastatin because simvastatin isn't as strong a statin because of some very strong congestive heart meds that impact the liver and kidneys. Factors that can change liver functions include weight gain, alcohol consumption, exercise levels and diet, so it takes a health professional, which I'm not, to ferret out cause for blood test changes.
Avatar m tn 5 or 2g 2g can lower healthy bacteria in the stomach of some so probiotics are suggested on the 2g dose of alinia and on simvastatin it is better to check main blood tests, liver tests and creatinine for kidneys every 6 months
Avatar m tn this is what trials found while what they say on the drug is not supported by trials and not supported by liver experts the high dose have had extremely rare rise of alt which dont mean liver damage as we now know, in any case just as a extra safety check alt/ast and creatinine monthly, if you get an alt rise we must then check if it is immune activation and lowering of hbvdna and hbsag or drugs toxicity and this is simple if alt rise a lot (over 200) and hbsag and hbvdna rise or stay stable fo
428155 tn?1203688894 in New Zealand), which my GP had prescribed me 2 years beforehand to control my cholesterol level. I stopped simvastatin and all fibrillations have disappeared. As I was taking simvastatin, I was in fibrillation 17% of the time; 1 month after I stopped simvastatin, the level was down to 0%. I am now experimenting with alternative cholesterol control methods: Omega 3 gels, ground linseed, charcoal.
1094370 tn?1317134825 Diseases that Cause Elevated Liver Enzymes in the Blood The most common diseases causing abnormally elevated ALT and AST are acute viral hepatitis, such as hepatitis A or B, chronic viral hepatitis, such hepatitis B or C, cirrhosis of the liver (scarring of the liver due to long standing inflammation of the liver), liver damage from alcohol abuse or alcoholic fatty liver, hemochromatosis (a genetic condition causing long standing liver damage due to iron build up in the liver), and diminished
Avatar f tn Would you rather lower your cholesterol or double your chances of liver damage? Any drug is processed by, and therefore taxes the liver, the more medications the more difficult it is for your liver. However, as a former drinker with high cholesterol, I have found that my blood pressure and liver enzyme tests are far more normal than when I was drinking. Please consider what is most important to you, your health or your alcohol intake.
Avatar m tn yes and no, if you have good antioxidant defence your liver can sty in a balance between damage and regeneration with no liver damage t all.alt is very poor as liver damage indicator but useful with all other parameters for doctor interpretation for exmple i regressed my fibrosis with alt 40-50, another one my not regress it even if lt 20....too many factors involved Appearing of HBSAB <2 IU/ML is what condiction?
329165 tn?1515471990 s a controversial question, but let me point out that NO studies have been done to prove any long term damage from statins. Remember, statins have been around since 1987 so they have 25 years of data to look at. In fact, as researchers are starting to do meta-analysis which roll up almost 200,000 participants in multiple trials do not show any long term damage or reactions. In fact, statins users are still protected from their use for up to 5 years after stopping their use.
Avatar m tn curious if stef2011 or studyforhope or StephenCastlecrag know whether simvastatin by itself can reduce viral load? I've read about the effects in conjunction with NUCS but I'm curious if sim is effective alone.
Avatar f tn anticolesterol and anidiabetes drugs are active on hbv too so you can take drugs like simvastatin and similar or rostiglitazone (or similar name) if needed avoid alcool fat foods and meat, these ones as little as possible you should also check your liver with fibroscan yearly to check the liver damage (the only machine that can tell liver damage) so you are safe...