Ribavirin and pregnancy

Common Questions and Answers about Ribavirin and pregnancy

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Avatar n tn Ribavirin has a longer half life than interferon. The levels for both gradually come down to zero over time. It is a few weeks with interferon and a few months with ribavirin.
Avatar f tn Does anyone know of an actual case of pregnancy and the father is using Ribavirin Ribavirin-interferon-alfa-2a during conception? Need to know the outcome.
Avatar f tn Hi, My partner is on the Interferon program, and Ribavirin is part of that treatment. He has been told that he should use 2 forms of contraception during treatment as well as for 6 months post treatment, and looking online, I see that this is primarily related to possible pregnancy. I have had an hysterectomy, so would like to know if we still need to use 2 methods of contraception, or any contraception at all in fact. Many thanks for any assistance!
Avatar f tn Does anyone know of an actual case of pregnancy and the father is using Ribavirin during conception? Need to know the outcome.
Avatar n tn been eating healthy and exercising...we have been talking about having a baby for awhile. im 30yrs old and my eggs are not getting any younger....
609800 tn?1221013204 It's kind of a gamble and I would personally not plan a pregnancy and put my child at risk to be born with the silent killer. I would treat first and become pregnant afterward. Just my opinion.
Avatar n tn Pregnancy is also not considered to cause deterioration of liver disease in women who have hepatitis C. Women with hepatitis C on treatment (pegylated interferon and ribavirin) are required to use two forms of contraception (one for each partner) to ensure they do not become pregnant during their treatment, and for six months following the end of treatment. This is because pegylated interferon and especially ribavirin can cause birth defects.
Avatar n tn Otherwise, enjoying a ifn/riba - free few months and feeling well.
Avatar f tn I am sorry you are faced with this circumstance and hope things work out. I don't know what the chances are for your baby to be healthy. Ribavirin carries strong warnings against becoming pregnant during treatment and for 6 months after treatment. This warning applies to the female if she is on Ribavirin and it also applies to the female if her partner is on Ribavirin.
Avatar f tn In addition, Ribavirin has a multiple dose half-life of 12 days, and it may persist in non-plasma compartments for as long as 6 months. Therefore, Ribavirin, including Ribavirin tablets, is contraindicated in women who are pregnant and in the male partners of women who are pregnant. Extreme care must be taken to avoid pregnancy during therapy and for 6 months after completion of therapy in both female patients and in female partners of male patients who are taking Ribavirin therapy.
Avatar n tn the Ribavirin Pregnancy Registry. Roberts SS. Ribavirin Pregnancy Registry Coordinating Center at Kendle International, Inc., Wilmington, NC, USA. ***@**** Ribavirin, used in combination with an interferon, is used for the treatment of chronic hepatitis C. Ribavirin is a Federal Drug Administration Pregnancy Category X product, indicating that its use is contraindicated in women who are pregnant.
Avatar m tn html Ribavirin Pregnancy Warnings Ribavirin has been assigned to pregnancy category X by the FDA. Nearly all animal studies have revealed evidence of embryolethality and teratogenicity. There are no controlled data in human pregnancies. One published case reports the uneventful use of ribavirin at 33 weeks gestation. Ribavirin therapy is contraindicated in women who are pregnant and in the male partners of women who are pregnant.
Avatar f tn Clearly, the current experience with intravenous ribavirin in the treatment of SARS is likely to result in much higher fetal exposure, and current recommendations include avoidance of the drug during pregnancy and lactation. Given the prolonged intracellular half-life and the current lack of knowledge in this regard, effective contraception should be practised by women who receive ribavirin, during treatment and for at least 6 months after treatment is completed.
Avatar n tn as long as you are not treating your Hep C yet then all should be fine. They just warn seriously about treating with Ribavirin and pregnancy. After the baby is born if you do decide to treat then it will be ok also.
Avatar f tn Manufacturer’s press releases suggest release of the drug Telaprevir might occur as early as 2011. The new drugs will initially be used in conjunction with interferon and ribavirin, but should increase efficacy and possibly reduce duration of HCV therapy.
Avatar n tn You absolutely CANNOT get pregnant while on interferon and ribavirin. The ribavirin, from what I understand, alters your rna while on treatment. It takes a full 6 months after finishing treatment for all of your cells to be replaced by new cells that have not been affected by the ribavirin. My doctor told me that even if I were to get pregant 5.5 months after stopping treatment, it would be very very bad.
Avatar n tn Because animal reproduction studies are not always predictive of human response, HEPSERA should be used during pregnancy only if clearly needed and after careful consideration of the risks and benefits. Pregnancy Registry To monitor fetal outcomes of pregnant women exposed to HEPSERA, a pregnancy registry has been established. Healthcare providers are encouraged to register patients by calling 1-800-258-4263.
Avatar n tn Do a google on hepc and pregnancy and you'll find plenty of info. When I was diagnosed, my second child was 9 months old and they told me to stop breastfeeding. My understanding is that that is no longer the recommendation--I'm not a doctor and I'm not 100% certain, but I think that breastfeeding is no risk. Good luck to you.
Avatar n tn The manufacturers contra-indications clearly state that the patient must be at least 6 mths post Tx prior to initiating pregnancy. Pls read Ribavirin instruction insert on Roche or Schering web sites. If the decision was my, I would consider waiting till Nov, after receiving additional results from your 12 mth follow-up check. BTW...... Good luck & I hope that you make the right decision :>) the Kid PS-In Israel, where I live, we're all too aware of the actions by terrorists.
Avatar m tn I am very sorry that you are in this situation. According to the information about Ribavirin, getting pregnant must be avoided in women taking the drug and if their male partners are taking the drug. Exposure to the drug, regardless of how the exposure takes place, (woman taking the drug, partner taking the drug) can result in severe fetal defects. His doctor should have discussed this with both of you and both you and he should be using precautions to avoid pregnancy.
Avatar n tn Ribavirin causes fetal death and deformity in lab animals. To get an idea of the seriousness of exposure, go to http://www.ribavirinpregnancyregistry.com/dlfiles/2009/RibavirinPedBirthDefectVersion1.1.pdf An OB probably knows about these issues but may need to consult with the doctor who treated your HCV. This is a terribly serious issue. Good luck.
Avatar f tn Thee is a ribavirin registry that may be helpful. I have no experience with it so I can't be sure. But here is the link: http://www.ribavirinpregnancyregistry.com/dlfiles/2011/RibavirinPregnancyRegistrySlideSetJul2011.
Avatar f tn I am 30 years old and have finished Peg Interferon and Ribavirin treatment for Hepatitis C Genotype 2(24 weeks) about 6 months ago. I have had no virus detectable since about 8 weeks in the treatment. I want to become pregnant now. What are the risk factors?
Avatar n tn Just don't do it if you are on interferon and ribavirin until you've been off the drugs at the very least 6 months is the recommendation I've heard.
Avatar f tn I am 30 years old and have finished Peg Interferon and Ribavirin treatment for Hepatitis C Genotype 2(24 weeks) about 6 months ago. I have had no virus detectable since about 8 weeks in the treatment. I want to become pregnant now. What are the risk factors?
Avatar n tn It's been two years since I completed my treatment with ribavirin and am trying to get pregnant. I recently had a miscarriage at 6 weeks, and began to wonder if the treatment may not have caused any damage to my eggs. Could you get pregnant without any problems? Please tell me how was the end of his story, and if you hear of other cases of pregnancy ...
1654177 tn?1319842094 Congrats on getting started Fri. remember side effects are different for everyone.. >you are young and that very well may be in your favor there. The Ribavirin labeling says you should not try to conceive while treating and for at least six months post tx. Some ..it seems only feel comfortable waiting somewhat longer........ possibly a year. Good luck...
1586675 tn?1300908695 NYgirl's prognostic of a one year wait period after tx and before pregnancy sounds quite reasonable... i had suspected that the riba has some heavy duty effect on reproductive organs... considering my age (40 on may 8) i may want to start considering the adoption option which is fine absolutely but... you know... i suppose most women know what i am talking about... well c'est la vie :) thank you again very much.
Avatar n tn so how should we think about these things if questioning pregnancy problems? it's a tough one and clearly alot of people have no problems getting pregnant at all with hepc so it's hard to know if that is the cause... just curious what your thoughts are about these things...i know you have been through alot and have a lot of wisdom in these matters...